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Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.
Augert, Arnaud; Eastwood, Emily; Ibrahim, Ali H; Wu, Nan; Grunblatt, Eli; Basom, Ryan; Liggitt, Denny; Eaton, Keith D; Martins, Renato; Poirier, John T; Rudin, Charles M; Milletti, Francesca; Cheng, Wei-Yi; Mack, Fiona; MacPherson, David.
Afiliación
  • Augert A; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA.
  • Eastwood E; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA.
  • Ibrahim AH; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA.
  • Wu N; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA.
  • Grunblatt E; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA.
  • Basom R; Genomics and Bioinformatics Shared Resource, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA.
  • Liggitt D; Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA.
  • Eaton KD; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA 98109, USA.
  • Martins R; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA 98109, USA.
  • Poirier JT; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Rudin CM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Milletti F; Pharmaceutical Research and Early Development, Roche Innovation Center, New York, NY 10016, USA.
  • Cheng WY; Pharmaceutical Research and Early Development, Roche Innovation Center, New York, NY 10016, USA.
  • Mack F; Pharmaceutical Research and Early Development, Roche Innovation Center, New York, NY 10016, USA.
  • MacPherson D; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109, USA. dmacpher@fredhutch.org.
Sci Signal ; 12(567)2019 02 05.
Article en En | MEDLINE | ID: mdl-30723171
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Ensayos Antitumor por Modelo de Xenoinjerto / Inhibidores Enzimáticos / Receptores Notch / Carcinoma Pulmonar de Células Pequeñas / Histona Demetilasas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Ensayos Antitumor por Modelo de Xenoinjerto / Inhibidores Enzimáticos / Receptores Notch / Carcinoma Pulmonar de Células Pequeñas / Histona Demetilasas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Signal Asunto de la revista: CIENCIA / FISIOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos