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Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism.
Malone, Samuel Andrew; Papadakis, Georgios E; Messina, Andrea; Mimouni, Nour El Houda; Trova, Sara; Imbernon, Monica; Allet, Cecile; Cimino, Irene; Acierno, James; Cassatella, Daniele; Xu, Cheng; Quinton, Richard; Szinnai, Gabor; Pigny, Pascal; Alonso-Cotchico, Lur; Masgrau, Laura; Maréchal, Jean-Didier; Prevot, Vincent; Pitteloud, Nelly; Giacobini, Paolo.
Afiliación
  • Malone SA; Jean-Pierre Aubert Research Center (JPArc), Laboratory of Development and Plasticity of the Neuroendocrine Brain, Inserm, UMR-S 1172, Lille, France.
  • Papadakis GE; University of Lille, FHU 1, 000 Days for Health, Lille, France.
  • Messina A; Faculty of Biology and Medicine, Service of Endocrinology, Diabetology and Metabolism, University Hospital, Lausanne, Switzerland.
  • Mimouni NEH; Faculty of Biology and Medicine, Service of Endocrinology, Diabetology and Metabolism, University Hospital, Lausanne, Switzerland.
  • Trova S; Jean-Pierre Aubert Research Center (JPArc), Laboratory of Development and Plasticity of the Neuroendocrine Brain, Inserm, UMR-S 1172, Lille, France.
  • Imbernon M; University of Lille, FHU 1, 000 Days for Health, Lille, France.
  • Allet C; Jean-Pierre Aubert Research Center (JPArc), Laboratory of Development and Plasticity of the Neuroendocrine Brain, Inserm, UMR-S 1172, Lille, France.
  • Cimino I; University of Lille, FHU 1, 000 Days for Health, Lille, France.
  • Acierno J; Jean-Pierre Aubert Research Center (JPArc), Laboratory of Development and Plasticity of the Neuroendocrine Brain, Inserm, UMR-S 1172, Lille, France.
  • Cassatella D; University of Lille, FHU 1, 000 Days for Health, Lille, France.
  • Xu C; Jean-Pierre Aubert Research Center (JPArc), Laboratory of Development and Plasticity of the Neuroendocrine Brain, Inserm, UMR-S 1172, Lille, France.
  • Quinton R; University of Lille, FHU 1, 000 Days for Health, Lille, France.
  • Szinnai G; Jean-Pierre Aubert Research Center (JPArc), Laboratory of Development and Plasticity of the Neuroendocrine Brain, Inserm, UMR-S 1172, Lille, France.
  • Pigny P; Faculty of Biology and Medicine, Service of Endocrinology, Diabetology and Metabolism, University Hospital, Lausanne, Switzerland.
  • Alonso-Cotchico L; Faculty of Biology and Medicine, Service of Endocrinology, Diabetology and Metabolism, University Hospital, Lausanne, Switzerland.
  • Masgrau L; Faculty of Biology and Medicine, Service of Endocrinology, Diabetology and Metabolism, University Hospital, Lausanne, Switzerland.
  • Maréchal JD; Institute of Genetic Medicine, University of Newcastle-upon-Tyne, Newcastle-upon-Tyne, United Kingdom.
  • Prevot V; Pediatric Endocrinology and Diabetology, University of Basel Children's Hospital, Basel, Switzerland.
  • Pitteloud N; CHU Lille, Laboratoire de Biochimie et Hormonologie, Centre de Biologie Pathologie, Lille, France.
  • Giacobini P; Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Elife ; 82019 07 10.
Article en En | MEDLINE | ID: mdl-31291191
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Hormona Liberadora de Gonadotropina / Hormona Antimülleriana / Hipogonadismo / Neuronas Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male Idioma: En Revista: Elife Año: 2019 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Hormona Liberadora de Gonadotropina / Hormona Antimülleriana / Hipogonadismo / Neuronas Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Animals / Female / Humans / Male Idioma: En Revista: Elife Año: 2019 Tipo del documento: Article País de afiliación: Francia