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Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Guan, Jane; Zhou, Wei; Hafner, Marc; Blake, Robert A; Chalouni, Cecile; Chen, Irene P; De Bruyn, Tom; Giltnane, Jennifer M; Hartman, Steven J; Heidersbach, Amy; Houtman, Rene; Ingalla, Ellen; Kategaya, Lorn; Kleinheinz, Tracy; Li, Jun; Martin, Scott E; Modrusan, Zora; Nannini, Michelle; Oeh, Jason; Ubhayakar, Savita; Wang, Xiaojing; Wertz, Ingrid E; Young, Amy; Yu, Mamie; Sampath, Deepak; Hager, Jeffrey H; Friedman, Lori S; Daemen, Anneleen; Metcalfe, Ciara.
Afiliación
  • Guan J; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Zhou W; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Hafner M; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, USA.
  • Blake RA; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.
  • Chalouni C; Department of Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Chen IP; Department of Medicine, UCSF, San Francisco, CA 94143, USA.
  • De Bruyn T; Department of Drug Metabolism and Pharmacokinetics, Genentech, South San Francisco, CA 94080, USA.
  • Giltnane JM; Department of Pathology, Genentech, South San Francisco, CA 94080, USA.
  • Hartman SJ; Theravance Biopharma, South San Francisco, CA 94080, USA.
  • Heidersbach A; Department of Molecular Biology, Genentech, South San Francisco, CA 94080, USA.
  • Houtman R; Department of Research and Development, PamGene, 5211 HH's-Hertogenbosch, the Netherlands.
  • Ingalla E; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Kategaya L; Ideaya Biosciences, South San Francisco, CA 94080, USA.
  • Kleinheinz T; Department of Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA 94080, USA.
  • Li J; Department of Discovery Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Martin SE; Department of Discovery Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Modrusan Z; Department of Molecular Biology, Genentech, South San Francisco, CA 94080, USA.
  • Nannini M; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Oeh J; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Ubhayakar S; Department of Medicine, UCSF, San Francisco, CA 94143, USA.
  • Wang X; Department of Discovery Chemistry, Genentech, South San Francisco, CA 94080, USA.
  • Wertz IE; Department of Discovery Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Young A; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Yu M; Department of Discovery Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Sampath D; Department of Research, Ultragenyx, Novato, CA 94949, USA.
  • Hager JH; Ideaya Biosciences, South San Francisco, CA 94080, USA.
  • Friedman LS; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA.
  • Daemen A; Department of Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, USA.
  • Metcalfe C; Department of Translational Oncology, Genentech, South San Francisco, CA 94080, USA. Electronic address: metcalfe.ciara@gene.com.
Cell ; 178(4): 949-963.e18, 2019 08 08.
Article en En | MEDLINE | ID: mdl-31353221
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptores de Estrógenos / Antagonistas del Receptor de Estrógeno / Fulvestrant Límite: Animals / Female / Humans Idioma: En Revista: Cell Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Receptores de Estrógenos / Antagonistas del Receptor de Estrógeno / Fulvestrant Límite: Animals / Female / Humans Idioma: En Revista: Cell Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos