Evaluation of immunogenicity and protective effect of DNA vaccine encoding surface antigen1 (SAG1) of Toxoplasma gondii and TLR-5 ligand as a genetic adjuvant against acute toxoplasmosis in BALB/c mice.

Maraghi, Sharif; Ghadiri, Ata A; Tavalla, Mehdi; Shojaee, Saeedeh; Abdizadeh, Rahman

Maraghi, Sharif; Ghadiri, Ata A; Tavalla, Mehdi; Shojaee, Saeedeh; Abdizadeh, Rahman.

Afiliación

Maraghi S; Department of Medical Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR, Iran; Institute of Health Research, Thalassemia and Hemoglobinopathy Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR, Iran.
Ghadiri AA; Department of Immunology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR, Iran; Cell and Molecular Research Center, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR, Iran.
Tavalla M; Department of Medical Parasitology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR, Iran.
Shojaee S; Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences Tehran, IR, Iran.
Abdizadeh R; Department of Medical Parasitology and Mycology, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, IR, Iran. Electronic address: R_abdizadeh@yahoo.com.

Biologicals ; 62: 39-49, 2019 Nov.

Article en En | MEDLINE | ID: mdl-31610951

Asunto(s)

Adyuvantes Inmunológicos/farmacología; Antígenos de Protozoos/inmunología; Flagelina/inmunología; Inmunogenicidad Vacunal; Proteínas Protozoarias/inmunología; Vacunas Antiprotozoos/inmunología; Salmonella typhimurium/inmunología; Receptor Toll-Like 5/agonistas; Toxoplasma/inmunología; Toxoplasmosis/prevención & control; Vacunas de ADN/inmunología; Enfermedad Aguda; Animales; Antígenos de Protozoos/genética; Femenino; Flagelina/genética; Humanos; Ratones; Ratones Endogámicos BALB C; Proteínas Protozoarias/genética; Vacunas Antiprotozoos/genética; Salmonella typhimurium/genética; Receptor Toll-Like 5/inmunología; Toxoplasma/genética; Toxoplasmosis/genética; Toxoplasmosis/inmunología; Vacunas de ADN/genética

Palabras clave

Adjuvant; BALB/C mice; DNA vaccine; Flagellin; Surface antigen 1; Toll-like receptor 5; Toxoplasma gondii

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Salmonella typhimurium / Toxoplasma / Proteínas Protozoarias / Toxoplasmosis / Adyuvantes Inmunológicos / Vacunas Antiprotozoos / Vacunas de ADN / Receptor Toll-Like 5 / Flagelina / Inmunogenicidad Vacunal Tipo de estudio: Evaluation_studies Límite: Animals / Female / Humans Idioma: En Revista: Biologicals Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Irán

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