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Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.
Wang, Guangchuan; Chow, Ryan D; Bai, Zhigang; Zhu, Lvyun; Errami, Youssef; Dai, Xiaoyun; Dong, Matthew B; Ye, Lupeng; Zhang, Xiaoya; Renauer, Paul A; Park, Jonathan J; Shen, Li; Ye, Hanghui; Fuchs, Charles S; Chen, Sidi.
Afiliación
  • Wang G; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Chow RD; System Biology Institute, Yale University, West Haven, CT, USA.
  • Bai Z; Center for Cancer Systems Biology, Yale University, West Haven, CT, USA.
  • Zhu L; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Errami Y; System Biology Institute, Yale University, West Haven, CT, USA.
  • Dai X; Center for Cancer Systems Biology, Yale University, West Haven, CT, USA.
  • Dong MB; MD-PhD Program, Yale University, New Haven, CT, USA.
  • Ye L; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Zhang X; System Biology Institute, Yale University, West Haven, CT, USA.
  • Renauer PA; Center for Cancer Systems Biology, Yale University, West Haven, CT, USA.
  • Park JJ; Department of General Surgery, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
  • Shen L; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Ye H; System Biology Institute, Yale University, West Haven, CT, USA.
  • Fuchs CS; Center for Cancer Systems Biology, Yale University, West Haven, CT, USA.
  • Chen S; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Nat Immunol ; 20(11): 1494-1505, 2019 11.
Article en En | MEDLINE | ID: mdl-31611701
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Terapia Genética / Regulación Neoplásica de la Expresión Génica / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Inmunoterapia / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Terapia Genética / Regulación Neoplásica de la Expresión Génica / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Inmunoterapia / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos