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Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.
Werneburg, Sebastian; Jung, Jonathan; Kunjamma, Rejani B; Ha, Seung-Kwon; Luciano, Nicholas J; Willis, Cory M; Gao, Guangping; Biscola, Natalia P; Havton, Leif A; Crocker, Stephen J; Popko, Brian; Reich, Daniel S; Schafer, Dorothy P.
Afiliación
  • Werneburg S; Department of Neurobiology, Brudnik Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Jung J; Department of Neurobiology, Brudnik Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  • Kunjamma RB; Department of Neurology, University of Chicago, Chicago, IL 60637, USA.
  • Ha SK; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
  • Luciano NJ; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
  • Willis CM; Department of Neuroscience, University of Connecticut School of Medicine, Farmington, CT 06032, USA.
  • Gao G; Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA 01605, USA; Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, MA 01605, USA; Department of Microbiologic and Physiological Systems, University of Massachusetts Med
  • Biscola NP; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  • Havton LA; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
  • Crocker SJ; Department of Neuroscience, University of Connecticut School of Medicine, Farmington, CT 06032, USA.
  • Popko B; Department of Neurology, University of Chicago, Chicago, IL 60637, USA.
  • Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
  • Schafer DP; Department of Neurobiology, Brudnik Neuropsychiatric Research Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address: dorothy.schafer@umassmed.edu.
Immunity ; 52(1): 167-182.e7, 2020 01 14.
Article en En | MEDLINE | ID: mdl-31883839
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sinapsis / Tálamo / Complemento C3 / Microglía / Encefalomielitis Autoinmune Experimental / Esclerosis Múltiple Límite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sinapsis / Tálamo / Complemento C3 / Microglía / Encefalomielitis Autoinmune Experimental / Esclerosis Múltiple Límite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos