Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.

Mavrovic, Martina; Uvarov, Pavel; Delpire, Eric; Vutskits, Laszlo; Kaila, Kai; Puskarjov, Martin

Mavrovic, Martina; Uvarov, Pavel; Delpire, Eric; Vutskits, Laszlo; Kaila, Kai; Puskarjov, Martin.

Afiliación

Mavrovic M; Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Uvarov P; Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
Delpire E; Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.
Vutskits L; Neuroscience Center, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.
Kaila K; Department of Anesthesiology, Vanderbilt University, Nashville, TN, USA.
Puskarjov M; Department of Basic Neurosciences, University of Geneva Medical School, Geneva 4, Switzerland.

EMBO Rep ; 21(4): e48880, 2020 04 03.

Article en En | MEDLINE | ID: mdl-32064760

Asunto(s)

Apoptosis; Epilepsia; Neuronas/patología; Simportadores/genética; Apoptosis/genética; Cloruros/metabolismo; Humanos; Neuronas/metabolismo

Palabras clave

GABA; KCC2; cell death; chloride; cofilin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Apoptosis / Simportadores / Epilepsia / Neuronas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: Finlandia

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