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Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
Sulkowski, Parker L; Oeck, Sebastian; Dow, Jonathan; Economos, Nicholas G; Mirfakhraie, Lily; Liu, Yanfeng; Noronha, Katelyn; Bao, Xun; Li, Jing; Shuch, Brian M; King, Megan C; Bindra, Ranjit S; Glazer, Peter M.
Afiliación
  • Sulkowski PL; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Oeck S; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Dow J; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Economos NG; Department of Medical Oncology, University of Duisburg-Essen, Essen, Germany.
  • Mirfakhraie L; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Liu Y; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Noronha K; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Bao X; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
  • Li J; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
  • Shuch BM; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • King MC; Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
  • Bindra RS; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.
  • Glazer PM; Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Nature ; 582(7813): 586-591, 2020 06.
Article en En | MEDLINE | ID: mdl-32494005

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cromatina / Transducción de Señal / Reparación del ADN / Recombinación Homóloga / Neoplasias Límite: Humans Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cromatina / Transducción de Señal / Reparación del ADN / Recombinación Homóloga / Neoplasias Límite: Humans Idioma: En Revista: Nature Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos