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1.

Small airway fibroblasts from patients with chronic obstructive pulmonary disease exhibit cellular senescence.

Wrench, Catherine L; Baker, Jonathan R; Monkley, Sue; Fenwick, Peter S; Murray, Lynne; Donnelly, Louise E; Barnes, Peter J.

Am J Physiol Lung Cell Mol Physiol ; 326(3): L266-L279, 2024 Mar 01.

Article in English | MEDLINE | ID: mdl-38150543

2.

An Update on Outcomes for COPD Pharmacological Trials: A COPD Investigators Report - Reassessment of the 2008 American Thoracic Society/European Respiratory Society Statement on Outcomes for COPD Pharmacological Trials.

Cazzola, Mario; Rogliani, Paola; Barnes, Peter J; Blasi, Francesco; Celli, Bartolome; Hanania, Nicola A; Martinez, Fernando J; Miller, Bruce E; Miravitlles, Marc; Page, Clive P; Tal-Singer, Ruth; Matera, Maria Gabriella.

Am J Respir Crit Care Med ; 208(4): 374-394, 2023 08 15.

Article in English | MEDLINE | ID: mdl-37236628

3.

Air pollution and COPD: GOLD 2023 committee report.

Sin, Don D; Doiron, Dany; Agusti, Alvar; Anzueto, Antonio; Barnes, Peter J; Celli, Bartolome R; Criner, Gerard J; Halpin, David; Han, MeiLan K; Martinez, Fernando J; Montes de Oca, Maria; Papi, Alberto; Pavord, Ian; Roche, Nicolas; Singh, Dave; Stockley, Robert; Lopez Varlera, M Victorina; Wedzicha, Jadwiga; Vogelmeier, Claus; Bourbeau, Jean.

Eur Respir J ; 61(5)2023 05.

Article in English | MEDLINE | ID: mdl-36958741

4.

DEL-1, as an anti-neutrophil transepithelial migration molecule, inhibits airway neutrophilic inflammation in asthma.

Jia, Man; Fu, Heng; Jiang, Xinyu; Wang, Lina; Xu, Jiayan; Barnes, Peter J; Adcock, Ian M; Liu, Yi; He, Shujuan; Zhang, Fan; Yao, Lei; Sun, Peng; Yao, Xin.

Allergy ; 2023 Sep 08.

Article in English | MEDLINE | ID: mdl-37681299

5.

Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial.

Yu, Ly-Mee; Bafadhel, Mona; Dorward, Jienchi; Hayward, Gail; Saville, Benjamin R; Gbinigie, Oghenekome; Van Hecke, Oliver; Ogburn, Emma; Evans, Philip H; Thomas, Nicholas P B; Patel, Mahendra G; Richards, Duncan; Berry, Nicholas; Detry, Michelle A; Saunders, Christina; Fitzgerald, Mark; Harris, Victoria; Shanyinde, Milensu; de Lusignan, Simon; Andersson, Monique I; Barnes, Peter J; Russell, Richard E K; Nicolau, Dan V; Ramakrishnan, Sanjay; Hobbs, F D Richard; Butler, Christopher C.

Lancet ; 398(10303): 843-855, 2021 09 04.

Article in English | MEDLINE | ID: mdl-34388395

6.

Inhaled corticosteroids reduce senescence in endothelial progenitor cells from patients with COPD.

Paschalaki, Koralia; Rossios, Christos; Pericleous, Charis; MacLeod, Mairi; Rothery, Stephen; Donaldson, Gavin C; Wedzicha, Jadwiga A; Gorgoulis, Vassilis; Randi, Anna M; Barnes, Peter J.

Thorax ; 77(6): 616-620, 2022 06.

Article in English | MEDLINE | ID: mdl-35027472

7.

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis.

Evangelou, Konstantinos; Veroutis, Dimitris; Paschalaki, Koralia; Foukas, Periklis G; Lagopati, Nefeli; Dimitriou, Marios; Papaspyropoulos, Angelos; Konda, Bindu; Hazapis, Orsalia; Polyzou, Aikaterini; Havaki, Sophia; Kotsinas, Athanassios; Kittas, Christos; Tzioufas, Athanasios G; de Leval, Laurence; Vassilakos, Demetris; Tsiodras, Sotirios; Stripp, Barry R; Papantonis, Argyris; Blandino, Giovanni; Karakasiliotis, Ioannis; Barnes, Peter J; Gorgoulis, Vassilis G.

Eur Respir J ; 60(2)2022 08.

Article in English | MEDLINE | ID: mdl-35086840

8.

Autophagy in asthma and chronic obstructive pulmonary disease.

Barnes, Peter J; Baker, Jonathan; Donnelly, Louise E.

Clin Sci (Lond) ; 136(10): 733-746, 2022 05 27.

Article in English | MEDLINE | ID: mdl-35608088

9.

Hepcidin Is Essential for Alveolar Macrophage Function and Is Disrupted by Smoke in a Murine Chronic Obstructive Pulmonary Disease Model.

Perez, Elizabeth; Baker, Jonathan R; Di Giandomenico, Silvana; Kermani, Pouneh; Parker, Jacqueline; Kim, Kihwan; Yang, Jianjun; Barnes, Peter J; Vaulont, Sophie; Scandura, Joseph M; Donnelly, Louise E; Stout-Delgado, Heather; Cloonan, Suzanne M.

J Immunol ; 205(9): 2489-2498, 2020 11 01.

Article in English | MEDLINE | ID: mdl-32958690

10.

Sex and gender: modifiers of health, disease, and medicine.

Mauvais-Jarvis, Franck; Bairey Merz, Noel; Barnes, Peter J; Brinton, Roberta D; Carrero, Juan-Jesus; DeMeo, Dawn L; De Vries, Geert J; Epperson, C Neill; Govindan, Ramaswamy; Klein, Sabra L; Lonardo, Amedeo; Maki, Pauline M; McCullough, Louise D; Regitz-Zagrosek, Vera; Regensteiner, Judith G; Rubin, Joshua B; Sandberg, Kathryn; Suzuki, Ayako.

Lancet ; 396(10250): 565-582, 2020 08 22.

Article in English | MEDLINE | ID: mdl-32828189

11.

As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.

Bateman, Eric D; Reddel, Helen K; O'Byrne, Paul M; Barnes, Peter J; Zhong, Nanshan; Keen, Christina; Jorup, Carin; Lamarca, Rosa; Siwek-Posluszna, Agnieszka; FitzGerald, J Mark.

N Engl J Med ; 378(20): 1877-1887, 2018 May 17.

Article in English | MEDLINE | ID: mdl-29768147

12.

Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.

O'Byrne, Paul M; FitzGerald, J Mark; Bateman, Eric D; Barnes, Peter J; Zhong, Nanshan; Keen, Christina; Jorup, Carin; Lamarca, Rosa; Ivanov, Stefan; Reddel, Helen K.

N Engl J Med ; 378(20): 1865-1876, 2018 05 17.

Article in English | MEDLINE | ID: mdl-29768149

13.

The effect of low-dose corticosteroids and theophylline on the risk of acute exacerbations of COPD: the TASCS randomised controlled trial.

Jenkins, Christine R; Wen, Fu-Qiang; Martin, Allison; Barnes, Peter J; Celli, Bartolome; Zhong, Nan-Shan; Zheng, Jin-Ping; Scaria, Anish; Di Tanna, Gian-Luca; Bradbury, Thomas; Berend, Norbert.

Eur Respir J ; 57(6)2021 06.

Article in English | MEDLINE | ID: mdl-33334939

14.

Role of autophagy in regulating interleukin-10 and the responses to corticosteroids and statins in asthma.

Maneechotesuwan, Kittipong; Kasetsinsombat, Kanda; Wongkajornsilp, Adisak; Barnes, Peter J.

Clin Exp Allergy ; 51(12): 1553-1565, 2021 12.

Article in English | MEDLINE | ID: mdl-33423318

15.

Bronchial mucosal inflammation and illness severity in response to experimental rhinovirus infection in COPD.

Zhu, Jie; Mallia, Patrick; Footitt, Joseph; Qiu, Yusheng; Message, Simon D; Kebadze, Tatiana; Aniscenko, Julia; Barnes, Peter J; Adcock, Ian M; Kon, Onn M; Johnson, Malcolm; Contoli, Marco; Stanciu, Luminita A; Papi, Alberto; Jeffery, Peter K; Johnston, Sebastian L.

J Allergy Clin Immunol ; 146(4): 840-850.e7, 2020 10.

Article in English | MEDLINE | ID: mdl-32283204

16.

Senescence in COPD and Its Comorbidities.

Barnes, Peter J.

Annu Rev Physiol ; 79: 517-539, 2017 02 10.

Article in English | MEDLINE | ID: mdl-27959617

17.

Phenotypic comparison between smoking and non-smoking chronic obstructive pulmonary disease.

Salvi, Sundeep S; Brashier, Bill B; Londhe, Jyoti; Pyasi, Kanchan; Vincent, Vandana; Kajale, Shilpa S; Tambe, Sajid; Mandani, Kuldeep; Nair, Arjun; Mak, Sze Mun; Madas, Sapna; Juvekar, Sanjay; Donnelly, Louise E; Barnes, Peter J.

Respir Res ; 21(1): 50, 2020 Feb 12.

Article in English | MEDLINE | ID: mdl-32050955

18.

MicroRNA-570 is a novel regulator of cellular senescence and inflammaging.

Baker, Jonathan R; Vuppusetty, Chaitanya; Colley, Thomas; Hassibi, Shyreen; Fenwick, Peter S; Donnelly, Louise E; Ito, Kazuhiro; Barnes, Peter J.

FASEB J ; 33(2): 1605-1616, 2019 02.

Article in English | MEDLINE | ID: mdl-30156909

19.

Cellular Senescence as a Mechanism and Target in Chronic Lung Diseases.

Barnes, Peter J; Baker, Jonathan; Donnelly, Louise E.

Am J Respir Crit Care Med ; 200(5): 556-564, 2019 09 01.

Article in English | MEDLINE | ID: mdl-30860857

20.

Ezrin, a Membrane Cytoskeleton Cross-Linker Protein, as a Marker of Epithelial Damage in Asthma.

Jia, Man; Yan, Xiaoyi; Jiang, Xinyu; Wu, Yunhui; Xu, Jiayan; Meng, Yaqi; Yang, Yi; Shan, Xia; Zhang, Xiuwedi; Mao, Shan; Gu, Wei; Pavlidis, Stelios; Barnes, Peter J; Adcock, Ian M; Huang, Mao; Yao, Xin.

Am J Respir Crit Care Med ; 199(4): 496-507, 2019 02 15.

Article in English | MEDLINE | ID: mdl-30290132

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