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1.
IdeS, a secreted proteinase of Streptococcus pyogenes, is bound to a nuclease at the bacterial surface where it inactivates opsonizing IgG antibodies.
J Biol Chem
; 299(11): 105345, 2023 Nov.
Article
in English
| MEDLINE | ID: mdl-37838172
2.
Human IgG Increases Virulence of Streptococcus pyogenes through Complement Evasion.
J Immunol
; 200(10): 3495-3505, 2018 05 15.
Article
in English
| MEDLINE | ID: mdl-29626087
3.
Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS.
Mol Cell Proteomics
; 17(6): 1097-1111, 2018 06.
Article
in English
| MEDLINE | ID: mdl-29511047
4.
Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots.
J Biol Chem
; 293(35): 13578-13591, 2018 08 31.
Article
in English
| MEDLINE | ID: mdl-30002122
5.
Safety, immunogenicity, pharmacokinetics, and efficacy of degradation of anti-HLA antibodies by IdeS (imlifidase) in chronic kidney disease patients.
Am J Transplant
; 18(11): 2752-2762, 2018 11.
Article
in English
| MEDLINE | ID: mdl-29561066
6.
In vivo enzymatic modulation of IgG antibodies prevents immune complex-dependent skin injury.
Exp Dermatol
; 26(8): 691-696, 2017 08.
Article
in English
| MEDLINE | ID: mdl-27512946
7.
Saliva-Induced Clotting Captures Streptococci: Novel Roles for Coagulation and Fibrinolysis in Host Defense and Immune Evasion.
Infect Immun
; 84(10): 2813-23, 2016 10.
Article
in English
| MEDLINE | ID: mdl-27456827
8.
Functional and structural properties of a novel protein and virulence factor (Protein sHIP) in Streptococcus pyogenes.
J Biol Chem
; 289(26): 18175-88, 2014 Jun 27.
Article
in English
| MEDLINE | ID: mdl-24825900
9.
Identification of molecular mechanisms used by Finegoldia magna to penetrate and colonize human skin.
Mol Microbiol
; 94(2): 403-17, 2014 Oct.
Article
in English
| MEDLINE | ID: mdl-25164331
10.
Binding of complement inhibitor C4b-binding protein to a highly virulent Streptococcus pyogenes M1 strain is mediated by protein H and enhances adhesion to and invasion of endothelial cells.
J Biol Chem
; 288(45): 32172-32183, 2013 Nov 08.
Article
in English
| MEDLINE | ID: mdl-24064215
11.
Surface proteins of group G Streptococcus in different phases of growth: patterns of production and implications for the host-bacteria relationship.
Microbiology (Reading)
; 160(Pt 2): 279-286, 2014 Feb.
Article
in English
| MEDLINE | ID: mdl-24222616
12.
Streptococcal surface proteins activate the contact system and control its antibacterial activity.
J Biol Chem
; 287(30): 25010-8, 2012 Jul 20.
Article
in English
| MEDLINE | ID: mdl-22648411
13.
Streptococcus pyogenes in human plasma: adaptive mechanisms analyzed by mass spectrometry-based proteomics.
J Biol Chem
; 287(2): 1415-25, 2012 Jan 06.
Article
in English
| MEDLINE | ID: mdl-22117078
14.
A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function.
EMBO Mol Med
; 15(2): e16208, 2023 02 08.
Article
in English
| MEDLINE | ID: mdl-36507602
15.
Binding of albumin promotes bacterial survival at the epithelial surface.
J Biol Chem
; 286(4): 2469-76, 2011 Jan 28.
Article
in English
| MEDLINE | ID: mdl-21098039
16.
Antibacterial activity of the contact and complement systems is blocked by SIC, a protein secreted by Streptococcus pyogenes.
J Biol Chem
; 286(2): 1331-40, 2011 Jan 14.
Article
in English
| MEDLINE | ID: mdl-21068386
17.
Histidine-rich glycoprotein promotes bacterial entrapment in clots and decreases mortality in a mouse model of sepsis.
Blood
; 116(13): 2365-72, 2010 Sep 30.
Article
in English
| MEDLINE | ID: mdl-20587784
18.
Activation of the contact system at the surface of Fusobacterium necrophorum represents a possible virulence mechanism in Lemièrre's syndrome.
Infect Immun
; 79(8): 3284-90, 2011 Aug.
Article
in English
| MEDLINE | ID: mdl-21646449
19.
Heparin-binding protein: a diagnostic marker of acute bacterial meningitis.
Crit Care Med
; 39(4): 812-7, 2011 Apr.
Article
in English
| MEDLINE | ID: mdl-21200320
20.
Treatment of invasive streptococcal infection with a peptide derived from human high-molecular weight kininogen.
Blood
; 114(2): 444-51, 2009 Jul 09.
Article
in English
| MEDLINE | ID: mdl-19433860