1.
J Vet Dent
; 12(3): 87-91, 1995 Sep.
Article
in English
| MEDLINE
| ID: mdl-9693631
ABSTRACT
V3703 (Stomadhex) is a tablet with bioadhesive properties enabling it to remain in place for several hours after it has been placed on the oral mucosa. It continuously releases chlorhexidine and niacinamide. In a study conducted in 15 dogs, the tablets were well tolerated by the animals. The product significantly reduced (p < 0.05): dental plaque; quantitative periodontopathogen and total anaerobic bacterial counts; spirochetes; and halitosis when used daily over a 14 day period. Gingivitis was also reduced, though not significantly (p = 0.07). Stomadhex treatment can provide a carry-over effect following dental scaling by reducing oral microflora and retarding the reappearance of dental plaque.
Subject(s)
Anti-Infective Agents, Local/administration & dosage , Chlorhexidine/administration & dosage , Dental Plaque/veterinary , Dog Diseases/drug therapy , Halitosis/veterinary , Niacinamide/administration & dosage , Administration, Topical , Analysis of Variance , Animals , Bacteria, Anaerobic/drug effects , Colony Count, Microbial , Dental Plaque/drug therapy , Dental Plaque/microbiology , Dog Diseases/microbiology , Dogs , Drug Combinations , Gingivitis/drug therapy , Gingivitis/veterinary , Halitosis/drug therapy , Linear Models , Mouth Mucosa , Spirochaetales/drug effects , Tablets
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