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1.

Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation.

Nagaraj, Raghavendra; Sharpley, Mark S; Chi, Fangtao; Braas, Daniel; Zhou, Yonggang; Kim, Rachel; Clark, Amander T; Banerjee, Utpal.

Cell ; 168(1-2): 210-223.e11, 2017 Jan 12.

Article in English | MEDLINE | ID: mdl-28086092

2.

DNA Demethylation Dynamics in the Human Prenatal Germline.

Gkountela, Sofia; Zhang, Kelvin X; Shafiq, Tiasha A; Liao, Wen-Wei; Hargan-Calvopiña, Joseph; Chen, Pao-Yang; Clark, Amander T.

Cell ; 161(6): 1425-36, 2015 Jun 04.

Article in English | MEDLINE | ID: mdl-26004067

3.

Modelling human blastocysts by reprogramming fibroblasts into iBlastoids.

Liu, Xiaodong; Tan, Jia Ping; Schröder, Jan; Aberkane, Asma; Ouyang, John F; Mohenska, Monika; Lim, Sue Mei; Sun, Yu B Y; Chen, Joseph; Sun, Guizhi; Zhou, Yichen; Poppe, Daniel; Lister, Ryan; Clark, Amander T; Rackham, Owen J L; Zenker, Jennifer; Polo, Jose M.

Nature ; 591(7851): 627-632, 2021 Mar.

Article in English | MEDLINE | ID: mdl-33731926

4.

Reprogramming roadmap reveals route to human induced trophoblast stem cells.

Liu, Xiaodong; Ouyang, John F; Rossello, Fernando J; Tan, Jia Ping; Davidson, Kathryn C; Valdes, Daniela S; Schröder, Jan; Sun, Yu B Y; Chen, Joseph; Knaupp, Anja S; Sun, Guizhi; Chy, Hun S; Huang, Ziyi; Pflueger, Jahnvi; Firas, Jaber; Tano, Vincent; Buckberry, Sam; Paynter, Jacob M; Larcombe, Michael R; Poppe, Daniel; Choo, Xin Yi; O'Brien, Carmel M; Pastor, William A; Chen, Di; Leichter, Anna L; Naeem, Haroon; Tripathi, Pratibha; Das, Partha P; Grubman, Alexandra; Powell, David R; Laslett, Andrew L; David, Laurent; Nilsson, Susan K; Clark, Amander T; Lister, Ryan; Nefzger, Christian M; Martelotto, Luciano G; Rackham, Owen J L; Polo, Jose M.

Nature ; 586(7827): 101-107, 2020 10.

Article in English | MEDLINE | ID: mdl-32939092

5.

Mammalian primordial germ cell specification.

Hancock, Grace V; Wamaitha, Sissy E; Peretz, Lior; Clark, Amander T.

Development ; 148(6)2021 03 15.

Article in English | MEDLINE | ID: mdl-33722957

6.

Human embryo implantation modelled in microfluidic channels.

Clark, Amander T.

Nature ; 573(7774): 350-351, 2019 09.

Article in English | MEDLINE | ID: mdl-31530907

7.

Human germline differentiation charts a new course.

Chen, Di; Clark, Amander T.

EMBO J ; 34(8): 975-7, 2015 Apr 15.

Article in English | MEDLINE | ID: mdl-25787856

8.

The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice.

Li, Ziwei; Yu, Juehua; Hosohama, Linzi; Nee, Kevin; Gkountela, Sofia; Chaudhari, Sonal; Cass, Ashley A; Xiao, Xinshu; Clark, Amander T.

EMBO J ; 34(6): 748-58, 2015 Mar 12.

Article in English | MEDLINE | ID: mdl-25519955

9.

Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin.

Li, Sisi; Yen, Linda; Pastor, William A; Johnston, Jonathan B; Du, Jiamu; Shew, Colin J; Liu, Wanlu; Ho, Jamie; Stender, Bryan; Clark, Amander T; Burlingame, Alma L; Daxinger, Lucia; Patel, Dinshaw J; Jacobsen, Steven E.

Proc Natl Acad Sci U S A ; 113(35): E5108-16, 2016 08 30.

Article in English | MEDLINE | ID: mdl-27528681

10.

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells.

O'Brien, Carmel M; Chy, Hun S; Zhou, Qi; Blumenfeld, Shiri; Lambshead, Jack W; Liu, Xiaodong; Kie, Joshua; Capaldo, Bianca D; Chung, Tung-Liang; Adams, Timothy E; Phan, Tram; Bentley, John D; McKinstry, William J; Oliva, Karen; McMurrick, Paul J; Wang, Yu-Chieh; Rossello, Fernando J; Lindeman, Geoffrey J; Chen, Di; Jarde, Thierry; Clark, Amander T; Abud, Helen E; Visvader, Jane E; Nefzger, Christian M; Polo, Jose M; Loring, Jeanne F; Laslett, Andrew L.

Stem Cells ; 35(3): 626-640, 2017 03.

Article in English | MEDLINE | ID: mdl-28009074

11.

Germline competency of human embryonic stem cells depends on eomesodermin.

Chen, Di; Liu, Wanlu; Lukianchikov, Anastasia; Hancock, Grace V; Zimmerman, Jill; Lowe, Matthew G; Kim, Rachel; Galic, Zoran; Irie, Naoko; Surani, M Azim; Jacobsen, Steven E; Clark, Amander T.

Biol Reprod ; 97(6): 850-861, 2017 01 01.

Article in English | MEDLINE | ID: mdl-29091993

12.

Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.

Xie, Wei; Song, Chunying; Young, Nicolas L; Sperling, Adam S; Xu, Feng; Sridharan, Rupa; Conway, Anne E; Garcia, Benjamin A; Plath, Kathrin; Clark, Amander T; Grunstein, Michael.

Mol Cell ; 33(4): 417-27, 2009 Feb 27.

Article in English | MEDLINE | ID: mdl-19250903

13.

Relationship between nucleosome positioning and DNA methylation.

Chodavarapu, Ramakrishna K; Feng, Suhua; Bernatavichute, Yana V; Chen, Pao-Yang; Stroud, Hume; Yu, Yanchun; Hetzel, Jonathan A; Kuo, Frank; Kim, Jin; Cokus, Shawn J; Casero, David; Bernal, Maria; Huijser, Peter; Clark, Amander T; Krämer, Ute; Merchant, Sabeeha S; Zhang, Xiaoyu; Jacobsen, Steven E; Pellegrini, Matteo.

Nature ; 466(7304): 388-92, 2010 Jul 15.

Article in English | MEDLINE | ID: mdl-20512117

14.

Hydrodynamic stretching of single cells for large population mechanical phenotyping.

Gossett, Daniel R; Tse, Henry T K; Lee, Serena A; Ying, Yong; Lindgren, Anne G; Yang, Otto O; Rao, Jianyu; Clark, Amander T; Di Carlo, Dino.

Proc Natl Acad Sci U S A ; 109(20): 7630-5, 2012 May 15.

Article in English | MEDLINE | ID: mdl-22547795

15.

Mammalian protein arginine methyltransferase 7 (PRMT7) specifically targets RXR sites in lysine- and arginine-rich regions.

Feng, You; Maity, Ranjan; Whitelegge, Julian P; Hadjikyriacou, Andrea; Li, Ziwei; Zurita-Lopez, Cecilia; Al-Hadid, Qais; Clark, Amander T; Bedford, Mark T; Masson, Jean-Yves; Clarke, Steven G.

J Biol Chem ; 288(52): 37010-25, 2013 Dec 27.

Article in English | MEDLINE | ID: mdl-24247247

16.

Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin.

Diaz Perez, Silvia V; Kim, Rachel; Li, Ziwei; Marquez, Victor E; Patel, Sanjeet; Plath, Kathrin; Clark, Amander T.

Hum Mol Genet ; 21(4): 751-64, 2012 Feb 15.

Article in English | MEDLINE | ID: mdl-22058289

17.

Derivation of human primordial germ cell-like cells in an embryonic-like culture.

Esfahani, Sajedeh Nasr; Zheng, Yi; Arabpour, Auriana; Irizarry, Agnes M Resto; Kobayashi, Norio; Xue, Xufeng; Shao, Yue; Zhao, Cheng; Agranonik, Nicole L; Sparrow, Megan; Hunt, Timothy J; Faith, Jared; Lara, Mary Jasmine; Wu, Qiu Ya; Silber, Sherman; Petropoulos, Sophie; Yang, Ran; Chien, Kenneth R; Clark, Amander T; Fu, Jianping.

Nat Commun ; 15(1): 167, 2024 Jan 02.

Article in English | MEDLINE | ID: mdl-38167821

18.

Transposable elements in early human embryo development and embryo models.

DiRusso, Jonathan A; Clark, Amander T.

Curr Opin Genet Dev ; 81: 102086, 2023 08.

Article in English | MEDLINE | ID: mdl-37441874

19.

Human embryo models made from pluripotent stem cells are not synthetic; they aren't embryos, either.

Landecker, Hannah L; Clark, Amander T.

Cell Stem Cell ; 30(10): 1290-1293, 2023 10 05.

Article in English | MEDLINE | ID: mdl-37802034

20.

TET1 facilitates specification of early human lineages including germ cells.

Hsu, Fei-Man; Wu, Qiu Ya; Fabyanic, Emily B; Wei, Alex; Wu, Hao; Clark, Amander T.

iScience ; 26(7): 107191, 2023 Jul 21.

Article in English | MEDLINE | ID: mdl-37456839

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