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1.
Fluorescent probes and degraders of the sterol transport protein Aster-A.
Bioorg Med Chem
; 103: 117673, 2024 Apr 01.
Article
in English
| MEDLINE | ID: mdl-38518734
2.
Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds.
Chembiochem
; 24(5): e202200555, 2023 03 01.
Article
in English
| MEDLINE | ID: mdl-36594441
3.
Structure, function and small molecule modulation of intracellular sterol transport proteins.
Bioorg Med Chem
; 68: 116856, 2022 08 15.
Article
in English
| MEDLINE | ID: mdl-35716590
4.
Covalent-Allosteric Inhibitors to Achieve Akt Isoform-Selectivity.
Angew Chem Int Ed Engl
; 58(52): 18823-18829, 2019 12 19.
Article
in English
| MEDLINE | ID: mdl-31584233
5.
Identification of non-conventional small molecule degraders and stabilizers of squalene synthase.
Chem Sci
; 14(45): 12973-12983, 2023 Nov 22.
Article
in English
| MEDLINE | ID: mdl-38023519
6.
Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions.
PLoS One
; 17(6): e0267651, 2022.
Article
in English
| MEDLINE | ID: mdl-35731722
7.
Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun
; 12(1): 5297, 2021 09 06.
Article
in English
| MEDLINE | ID: mdl-34489430
8.
Spotlight on AKT: Current Therapeutic Challenges.
ACS Med Chem Lett
; 11(3): 225-227, 2020 Mar 12.
Article
in English
| MEDLINE | ID: mdl-32184947
9.
Structural and chemical insights into the covalent-allosteric inhibition of the protein kinase Akt.
Chem Sci
; 10(12): 3573-3585, 2019 Mar 28.
Article
in English
| MEDLINE | ID: mdl-30996949
10.
Preclinical Efficacy of Covalent-Allosteric AKT Inhibitor Borussertib in Combination with Trametinib in KRAS-Mutant Pancreatic and Colorectal Cancer.
Cancer Res
; 79(9): 2367-2378, 2019 05 01.
Article
in English
| MEDLINE | ID: mdl-30858154
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