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1.

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.

Tarallo, Valeria; Hirano, Yoshio; Gelfand, Bradley D; Dridi, Sami; Kerur, Nagaraj; Kim, Younghee; Cho, Won Gil; Kaneko, Hiroki; Fowler, Benjamin J; Bogdanovich, Sasha; Albuquerque, Romulo J C; Hauswirth, William W; Chiodo, Vince A; Kugel, Jennifer F; Goodrich, James A; Ponicsan, Steven L; Chaudhuri, Gautam; Murphy, Michael P; Dunaief, Joshua L; Ambati, Balamurali K; Ogura, Yuichiro; Yoo, Jae Wook; Lee, Dong-ki; Provost, Patrick; Hinton, David R; Núñez, Gabriel; Baffi, Judit Z; Kleinman, Mark E; Ambati, Jayakrishna.

Cell ; 149(4): 847-59, 2012 May 11.

Article in English | MEDLINE | ID: mdl-22541070

2.

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.

Fukuda, Shinichi; Varshney, Akhil; Fowler, Benjamin J; Wang, Shao-Bin; Narendran, Siddharth; Ambati, Kameshwari; Yasuma, Tetsuhiro; Magagnoli, Joseph; Leung, Hannah; Hirahara, Shuichiro; Nagasaka, Yosuke; Yasuma, Reo; Apicella, Ivana; Pereira, Felipe; Makin, Ryan D; Magner, Eamonn; Liu, Xinan; Sun, Jian; Wang, Mo; Baker, Kirstie; Marion, Kenneth M; Huang, Xiwen; Baghdasaryan, Elmira; Ambati, Meenakshi; Ambati, Vidya L; Pandey, Akshat; Pandya, Lekha; Cummings, Tammy; Banerjee, Daipayan; Huang, Peirong; Yerramothu, Praveen; Tolstonog, Genrich V; Held, Ulrike; Erwin, Jennifer A; Paquola, Apua C M; Herdy, Joseph R; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Darwish, Shaban; Singh, Ramendra K; Mozaffari, Saghar; Bhattarai, Deepak; Kim, Kyung Bo; Hardin, James W; Bennett, Charles L; Hinton, David R; Hanson, Timothy E; Röver, Christian; Parang, Keykavous.

Proc Natl Acad Sci U S A ; 118(6)2021 02 09.

Article in English | MEDLINE | ID: mdl-33526699

3.

Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.

Wright, Charles B; Uehara, Hironori; Kim, Younghee; Yasuma, Tetsuhiro; Yasuma, Reo; Hirahara, Shuichiro; Makin, Ryan D; Apicella, Ivana; Pereira, Felipe; Nagasaka, Yosuke; Narendran, Siddharth; Fukuda, Shinichi; Albuquerque, Romulo; Fowler, Benjamin J; Bastos-Carvalho, Ana; Georgel, Philippe; Hatada, Izuho; Chang, Bo; Kerur, Nagaraj; Ambati, Balamurali K; Ambati, Jayakrishna; Gelfand, Bradley D.

Proc Natl Acad Sci U S A ; 117(5): 2579-2587, 2020 02 04.

Article in English | MEDLINE | ID: mdl-31964819

4.

NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis.

Basu, Soumyava; Fowler, Benjamin J; Kerur, Nagaraj; Arnvig, Kristine B; Rao, Narsing A.

Microb Pathog ; 114: 219-224, 2018 Jan.

Article in English | MEDLINE | ID: mdl-29180292

5.

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration.

Kaneko, Hiroki; Dridi, Sami; Tarallo, Valeria; Gelfand, Bradley D; Fowler, Benjamin J; Cho, Won Gil; Kleinman, Mark E; Ponicsan, Steven L; Hauswirth, William W; Chiodo, Vince A; Karikó, Katalin; Yoo, Jae Wook; Lee, Dong-ki; Hadziahmetovic, Majda; Song, Ying; Misra, Smita; Chaudhuri, Gautam; Buaas, Frank W; Braun, Robert E; Hinton, David R; Zhang, Qing; Grossniklaus, Hans E; Provis, Jan M; Madigan, Michele C; Milam, Ann H; Justice, Nikki L; Albuquerque, Romulo J C; Blandford, Alexander D; Bogdanovich, Sasha; Hirano, Yoshio; Witta, Jassir; Fuchs, Elaine; Littman, Dan R; Ambati, Balamurali K; Rudin, Charles M; Chong, Mark M W; Provost, Patrick; Kugel, Jennifer F; Goodrich, James A; Dunaief, Joshua L; Baffi, Judit Z; Ambati, Jayakrishna.

Nature ; 471(7338): 325-30, 2011 Mar 17.

Article in English | MEDLINE | ID: mdl-21297615

6.

DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.

Kim, Younghee; Tarallo, Valeria; Kerur, Nagaraj; Yasuma, Tetsuhiro; Gelfand, Bradley D; Bastos-Carvalho, Ana; Hirano, Yoshio; Yasuma, Reo; Mizutani, Takeshi; Fowler, Benjamin J; Li, Shengjian; Kaneko, Hiroki; Bogdanovich, Sasha; Ambati, Balamurali K; Hinton, David R; Hauswirth, William W; Hakem, Razqallah; Wright, Charles; Ambati, Jayakrishna.

Proc Natl Acad Sci U S A ; 111(45): 16082-7, 2014 Nov 11.

Article in English | MEDLINE | ID: mdl-25349431

7.

ERK1/2 activation is a therapeutic target in age-related macular degeneration.

Dridi, Sami; Hirano, Yoshio; Tarallo, Valeria; Kim, Younghee; Fowler, Benjamin J; Ambati, Balamurali K; Bogdanovich, Sasha; Chiodo, Vince A; Hauswirth, William W; Kugel, Jennifer F; Goodrich, James A; Ponicsan, Steven L; Hinton, David R; Kleinman, Mark E; Baffi, Judit Z; Gelfand, Bradley D; Ambati, Jayakrishna.

Proc Natl Acad Sci U S A ; 109(34): 13781-6, 2012 Aug 21.

Article in English | MEDLINE | ID: mdl-22869729

8.

Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.

Kleinman, Mark E; Kaneko, Hiroki; Cho, Won Gil; Dridi, Sami; Fowler, Benjamin J; Blandford, Alexander D; Albuquerque, Romulo J C; Hirano, Yoshio; Terasaki, Hiroko; Kondo, Mineo; Fujita, Takashi; Ambati, Balamurali K; Tarallo, Valeria; Gelfand, Bradley D; Bogdanovich, Sasha; Baffi, Judit Z; Ambati, Jayakrishna.

Mol Ther ; 20(1): 101-8, 2012 Jan.

Article in English | MEDLINE | ID: mdl-21988875

9.

Retractable Urology Three-Pronged Grasping Forceps for Removal of Large, Non-Magnetic Intraocular Foreign Bodies.

Brown, Jaime E; Fowler, Benjamin J; Channa, Roomasa.

Retin Cases Brief Rep ; 2023 Jan 17.

Article in English | MEDLINE | ID: mdl-36657155

10.

Ocular Findings Aid in Diagnosis of West Nile Virus.

Winward, Brandon K; Gottlieb, Justin L; Chang, Jonathan S; Bradbury, Luke; Maganti, Nenita; Pathak, Chintan; Fowler, Benjamin J.

WMJ ; 122(3): 208-212, 2023 Jul.

Article in English | MEDLINE | ID: mdl-37494654

11.

Case report: Vitreous hemorrhage as the presenting sign of retinal cavernous hemangioma in a newborn.

Fowler, Benjamin J; Simon, Lilla; Scott, Nathan L; Negron, Catherin I; Berrocal, Audina M.

Am J Ophthalmol Case Rep ; 23: 101174, 2021 Sep.

Article in English | MEDLINE | ID: mdl-34381923

12.

Postoperative Endophthalmitis Caused by Cutibacterium (Formerly Propionibacterium) Acnes: Case Series and Review.

Fowler, Benjamin J; Miller, Darlene; Yan, Xiaohe; Yannuzzi, Nicolas A; Flynn, Harry W.

Case Rep Ophthalmol ; 12(1): 1-10, 2021.

Article in English | MEDLINE | ID: mdl-33613244

13.

Comparison Between Graders in Detection of Diabetic Neovascularization With Swept Source Optical Coherence Tomography Angiography and Fluorescein Angiography.

Al-Khersan, Hasenin; Russell, Jonathan F; Lazzarini, Thomas A; Scott, Nathan L; Hinkle, John W; Patel, Nimesh A; Yannuzzi, Nicolas A; Fowler, Benjamin J; Hussain, Rehan M; Barikian, Anita; Sridhar, Jayanth; Russell, Stephen R; Haddock, Luis J; Smiddy, William E; Hariprasad, Seenu M; Shi, Yingying; Wang, Liang; Feuer, William; Gregori, Giovanni; Rosenfeld, Philip J.

Am J Ophthalmol ; 224: 292-300, 2021 04.

Article in English | MEDLINE | ID: mdl-33309812

14.

Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity.

Fukuda, Shinichi; Narendran, Siddharth; Varshney, Akhil; Nagasaka, Yosuke; Wang, Shao-Bin; Ambati, Kameshwari; Apicella, Ivana; Pereira, Felipe; Fowler, Benjamin J; Yasuma, Tetsuhiro; Hirahara, Shuichiro; Yasuma, Reo; Huang, Peirong; Yerramothu, Praveen; Makin, Ryan D; Wang, Mo; Baker, Kirstie L; Marion, Kenneth M; Huang, Xiwen; Baghdasaryan, Elmira; Ambati, Meenakshi; Ambati, Vidya L; Banerjee, Daipayan; Bonilha, Vera L; Tolstonog, Genrich V; Held, Ulrike; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Bhattarai, Deepak; Kim, Kyung Bo; Feldman, Sanford H; Aguirre, J Ignacio; Hinton, David R; Kerur, Nagaraj; Sadda, Srinivas R; Schumann, Gerald G; Gelfand, Bradley D; Ambati, Jayakrishna.

Sci Adv ; 7(40): eabj3658, 2021 Oct.

Article in English | MEDLINE | ID: mdl-34586848

15.

Sixth Cranial Nerve Palsy as the Presenting Sign of Metastatic Cholangiocarcinoma.

Fowler, Benjamin J; Lam, Byron L.

Int Med Case Rep J ; 13: 667-671, 2020.

Article in English | MEDLINE | ID: mdl-33262662

16.

Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development.

Ambati, Jayakrishna; Magagnoli, Joseph; Leung, Hannah; Wang, Shao-Bin; Andrews, Chris A; Fu, Dongxu; Pandey, Akshat; Sahu, Srabani; Narendran, Siddharth; Hirahara, Shuichiro; Fukuda, Shinichi; Sun, Jian; Pandya, Lekha; Ambati, Meenakshi; Pereira, Felipe; Varshney, Akhil; Cummings, Tammy; Hardin, James W; Edun, Babatunde; Bennett, Charles L; Ambati, Kameshwari; Fowler, Benjamin J; Kerur, Nagaraj; Röver, Christian; Leitinger, Norbert; Werner, Brian C; Stein, Joshua D; Sutton, S Scott; Gelfand, Bradley D.

Nat Commun ; 11(1): 4737, 2020 09 23.

Article in English | MEDLINE | ID: mdl-32968070

17.

Latent Sensitization in a Mouse Model of Ocular Neuropathic Pain.

Cho, Jooyoung; Bell, Nicholas; Botzet, Gregory; Vora, Paras; Fowler, Benjamin J; Donahue, Renee; Bush, Heather; Taylor, Bradley K; Albuquerque, Romulo J C.

Transl Vis Sci Technol ; 8(2): 6, 2019 Mar.

Article in English | MEDLINE | ID: mdl-30937216

18.

cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.

Kerur, Nagaraj; Fukuda, Shinichi; Banerjee, Daipayan; Kim, Younghee; Fu, Dongxu; Apicella, Ivana; Varshney, Akhil; Yasuma, Reo; Fowler, Benjamin J; Baghdasaryan, Elmira; Marion, Kenneth M; Huang, Xiwen; Yasuma, Tetsuhiro; Hirano, Yoshio; Serbulea, Vlad; Ambati, Meenakshi; Ambati, Vidya L; Kajiwara, Yuji; Ambati, Kameshwari; Hirahara, Shuichiro; Bastos-Carvalho, Ana; Ogura, Yuichiro; Terasaki, Hiroko; Oshika, Tetsuro; Kim, Kyung Bo; Hinton, David R; Leitinger, Norbert; Cambier, John C; Buxbaum, Joseph D; Kenney, M Cristina; Jazwinski, S Michal; Nagai, Hiroshi; Hara, Isao; West, A Phillip; Fitzgerald, Katherine A; Sadda, SriniVas R; Gelfand, Bradley D; Ambati, Jayakrishna.

Nat Med ; 24(1): 50-61, 2018 01.

Article in English | MEDLINE | ID: mdl-29176737

19.

Metamorphopsia in a Middle-aged Man.

Fowler, Benjamin J; Nguyen, Jimmy L; Sridhar, Jayanth.

JAMA Ophthalmol ; 139(9): 1039-1040, 2021 09 01.

Article in English | MEDLINE | ID: mdl-34264283

20.

A 56-year-old man with a unilateral central scotoma.

Shah, Khushali; Fowler, Benjamin J; Lin, Benjamin; Cavuoto, Kara M; Sridhar, Jayanth.

Digit J Ophthalmol ; 27(3): 56-59, 2021.

Article in English | MEDLINE | ID: mdl-34924885

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