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1.

The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.

de Mingo Pulido, Álvaro; Hänggi, Kay; Celias, Daiana P; Gardner, Alycia; Li, Jie; Batista-Bittencourt, Bruna; Mohamed, Eslam; Trillo-Tinoco, Jimena; Osunmakinde, Olabisi; Peña, Reymi; Onimus, Alexis; Kaisho, Tsuneyasu; Kaufmann, Johanna; McEachern, Kristen; Soliman, Hatem; Luca, Vincent C; Rodriguez, Paulo C; Yu, Xiaoqing; Ruffell, Brian.

Immunity ; 54(6): 1154-1167.e7, 2021 06 08.

Article in English | MEDLINE | ID: mdl-33979578

2.

moDCs, Less Problems.

Gardner, Alycia; Ruffell, Brian.

Immunity ; 48(1): 6-8, 2018 01 16.

Article in English | MEDLINE | ID: mdl-29343441

3.

Combating castration-resistant prostate cancer by co-targeting the epigenetic regulators EZH2 and HDAC.

Schade, Amy E; Kuzmickas, Ryan; Rodriguez, Carrie L; Mattioli, Kaia; Enos, Miriam; Gardner, Alycia; Cichowski, Karen.

PLoS Biol ; 21(4): e3002038, 2023 04.

Article in English | MEDLINE | ID: mdl-37104245

4.

Dendritic Cells and Cancer Immunity.

Gardner, Alycia; Ruffell, Brian.

Trends Immunol ; 37(12): 855-865, 2016 12.

Article in English | MEDLINE | ID: mdl-27793569

5.

A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.

Chaim, Isaac A; Gardner, Alycia; Wu, Jie; Iyama, Teruaki; Wilson, David M; Samson, Leona D.

Nucleic Acids Res ; 45(6): 3242-3252, 2017 04 07.

Article in English | MEDLINE | ID: mdl-28115629

6.

DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer.

Miller, Abigail L; Perurena, Naiara; Gardner, Alycia; Hinoue, Toshinori; Loi, Patrick; Laird, Peter W; Cichowski, Karen.

Cancer Res ; 83(11): 1800-1814, 2023 06 02.

Article in English | MEDLINE | ID: mdl-36939385

7.

Fucosylation of HLA-DRB1 regulates CD4⁺ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.

Lester, Daniel K; Burton, Chase; Gardner, Alycia; Innamarato, Patrick; Kodumudi, Krithika; Liu, Qian; Adhikari, Emma; Ming, Qianqian; Williamson, Daniel B; Frederick, Dennie T; Sharova, Tatyana; White, Michael G; Markowitz, Joseph; Cao, Biwei; Nguyen, Jonathan; Johnson, Joseph; Beatty, Matthew; Mockabee-Macias, Andrea; Mercurio, Matthew; Watson, Gregory; Chen, Pei-Ling; McCarthy, Susan; MoranSegura, Carlos; Messina, Jane; Thomas, Kerry L; Darville, Lancia; Izumi, Victoria; Koomen, John M; Pilon-Thomas, Shari A; Ruffell, Brian; Luca, Vincent C; Haltiwanger, Robert S; Wang, Xuefeng; Wargo, Jennifer A; Boland, Genevieve M; Lau, Eric K.

Nat Cancer ; 4(2): 222-239, 2023 02.

Article in English | MEDLINE | ID: mdl-36690875

8.

TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8⁺ T cell and XCR1⁺ dendritic cell spatial co-localization.

Gardner, Alycia; de Mingo Pulido, Álvaro; Hänggi, Kay; Bazargan, Sarah; Onimus, Alexis; Kasprzak, Agnieszka; Conejo-Garcia, Jose R; Rejniak, Katarzyna A; Ruffell, Brian.

J Immunother Cancer ; 10(1)2022 01.

Article in English | MEDLINE | ID: mdl-34987021

9.

Dendritic Cells and Their Role in Immunotherapy.

Gardner, Alycia; de Mingo Pulido, Álvaro; Ruffell, Brian.

Front Immunol ; 11: 924, 2020.

Article in English | MEDLINE | ID: mdl-32508825

10.

TIM-3 Regulates CD103⁺ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer.

de Mingo Pulido, Álvaro; Gardner, Alycia; Hiebler, Shandi; Soliman, Hatem; Rugo, Hope S; Krummel, Matthew F; Coussens, Lisa M; Ruffell, Brian.

Cancer Cell ; 33(1): 60-74.e6, 2018 01 08.

Article in English | MEDLINE | ID: mdl-29316433

11.

Reducing interferon'ce in stem cells.

Gardner, Alycia; Ruffell, Brian.

Nat Cell Biol ; 19(6): 597-599, 2017 May 31.

Article in English | MEDLINE | ID: mdl-28561058

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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.

moDCs, Less Problems.

Combating castration-resistant prostate cancer by co-targeting the epigenetic regulators EZH2 and HDAC.

Dendritic Cells and Cancer Immunity.

A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.

DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer.

Fucosylation of HLA-DRB1 regulates CD4⁺ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.

TIM-3 blockade enhances IL-12-dependent antitumor immunity by promoting CD8⁺ T cell and XCR1⁺ dendritic cell spatial co-localization.

Dendritic Cells and Their Role in Immunotherapy.

TIM-3 Regulates CD103⁺ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer.

Reducing interferon'ce in stem cells.