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1.

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies.

Chen, Yao-Qing; Wohlbold, Teddy John; Zheng, Nai-Ying; Huang, Min; Huang, Yunping; Neu, Karlynn E; Lee, Jiwon; Wan, Hongquan; Rojas, Karla Thatcher; Kirkpatrick, Ericka; Henry, Carole; Palm, Anna-Karin E; Stamper, Christopher T; Lan, Linda Yu-Ling; Topham, David J; Treanor, John; Wrammert, Jens; Ahmed, Rafi; Eichelberger, Maryna C; Georgiou, George; Krammer, Florian; Wilson, Patrick C.

Cell ; 173(2): 417-429.e10, 2018 04 05.

Article in English | MEDLINE | ID: mdl-29625056

2.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.

Saphire, Erica Ollmann; Schendel, Sharon L; Fusco, Marnie L; Gangavarapu, Karthik; Gunn, Bronwyn M; Wec, Anna Z; Halfmann, Peter J; Brannan, Jennifer M; Herbert, Andrew S; Qiu, Xiangguo; Wagh, Kshitij; He, Shihua; Giorgi, Elena E; Theiler, James; Pommert, Kathleen B J; Krause, Tyler B; Turner, Hannah L; Murin, Charles D; Pallesen, Jesper; Davidson, Edgar; Ahmed, Rafi; Aman, M Javad; Bukreyev, Alexander; Burton, Dennis R; Crowe, James E; Davis, Carl W; Georgiou, George; Krammer, Florian; Kyratsous, Christos A; Lai, Jonathan R; Nykiforuk, Cory; Pauly, Michael H; Rijal, Pramila; Takada, Ayato; Townsend, Alain R; Volchkov, Viktor; Walker, Laura M; Wang, Cheng-I; Zeitlin, Larry; Doranz, Benjamin J; Ward, Andrew B; Korber, Bette; Kobinger, Gary P; Andersen, Kristian G; Kawaoka, Yoshihiro; Alter, Galit; Chandran, Kartik; Dye, John M.

Cell ; 174(4): 938-952.e13, 2018 08 09.

Article in English | MEDLINE | ID: mdl-30096313

3.

Increased cathepsin S in Prdm1^-/- dendritic cells alters the T_FH cell repertoire and contributes to lupus.

Kim, Sun Jung; Schätzle, Sebastian; Ahmed, S Sohail; Haap, Wolfgang; Jang, Su Hwa; Gregersen, Peter K; Georgiou, George; Diamond, Betty.

Nat Immunol ; 18(9): 1016-1024, 2017 Sep.

Article in English | MEDLINE | ID: mdl-28692065

4.

IgG Fc domains that bind C1q but not effector FcÎ³ receptors delineate the importance of complement-mediated effector functions.

Lee, Chang-Han; Romain, Gabrielle; Yan, Wupeng; Watanabe, Makiko; Charab, Wissam; Todorova, Biliana; Lee, Jiwon; Triplett, Kendra; Donkor, Moses; Lungu, Oana I; Lux, Anja; Marshall, Nicholas; Lindorfer, Margaret A; Goff, Odile Richard-Le; Balbino, Bianca; Kang, Tae Hyun; Tanno, Hidetaka; Delidakis, George; Alford, Corrine; Taylor, Ronald P; Nimmerjahn, Falk; Varadarajan, Navin; Bruhns, Pierre; Zhang, Yan Jessie; Georgiou, George.

Nat Immunol ; 18(8): 889-898, 2017 Aug.

Article in English | MEDLINE | ID: mdl-28604720

5.

Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.

Soni, Chetna; Perez, Oriana A; Voss, William N; Pucella, Joseph N; Serpas, Lee; Mehl, Justin; Ching, Krystal L; Goike, Jule; Georgiou, George; Ippolito, Gregory C; Sisirak, Vanja; Reizis, Boris.

Immunity ; 52(6): 1022-1038.e7, 2020 06 16.

Article in English | MEDLINE | ID: mdl-32454024

6.

Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.

Lindesmith, Lisa C; McDaniel, Jonathan R; Changela, Anita; Verardi, Raffaello; Kerr, Scott A; Costantini, Veronica; Brewer-Jensen, Paul D; Mallory, Michael L; Voss, William N; Boutz, Daniel R; Blazeck, John J; Ippolito, Gregory C; Vinje, Jan; Kwong, Peter D; Georgiou, George; Baric, Ralph S.

Immunity ; 50(6): 1530-1541.e8, 2019 06 18.

Article in English | MEDLINE | ID: mdl-31216462

7.

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.

Krebs, Shelly J; Kwon, Young D; Schramm, Chaim A; Law, William H; Donofrio, Gina; Zhou, Kenneth H; Gift, Syna; Dussupt, Vincent; Georgiev, Ivelin S; Schätzle, Sebastian; McDaniel, Jonathan R; Lai, Yen-Ting; Sastry, Mallika; Zhang, Baoshan; Jarosinski, Marissa C; Ransier, Amy; Chenine, Agnes L; Asokan, Mangaiarkarasi; Bailer, Robert T; Bose, Meera; Cagigi, Alberto; Cale, Evan M; Chuang, Gwo-Yu; Darko, Samuel; Driscoll, Jefferson I; Druz, Aliaksandr; Gorman, Jason; Laboune, Farida; Louder, Mark K; McKee, Krisha; Mendez, Letzibeth; Moody, M Anthony; O'Sullivan, Anne Marie; Owen, Christopher; Peng, Dongjun; Rawi, Reda; Sanders-Buell, Eric; Shen, Chen-Hsiang; Shiakolas, Andrea R; Stephens, Tyler; Tsybovsky, Yaroslav; Tucker, Courtney; Verardi, Raffaello; Wang, Keyun; Zhou, Jing; Zhou, Tongqing; Georgiou, George; Alam, S Munir; Haynes, Barton F; Rolland, Morgane.

Immunity ; 50(3): 677-691.e13, 2019 03 19.

Article in English | MEDLINE | ID: mdl-30876875

8.

Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

Pataskar, Abhijeet; Champagne, Julien; Nagel, Remco; Kenski, Juliana; Laos, Maarja; Michaux, Justine; Pak, Hui Song; Bleijerveld, Onno B; Mordente, Kelly; Navarro, Jasmine Montenegro; Blommaert, Naomi; Nielsen, Morten M; Lovecchio, Domenica; Stone, Everett; Georgiou, George; de Gooijer, Mark C; van Tellingen, Olaf; Altelaar, Maarten; Joosten, Robbie P; Perrakis, Anastassis; Olweus, Johanna; Bassani-Sternberg, Michal; Peeper, Daniel S; Agami, Reuven.

Nature ; 603(7902): 721-727, 2022 03.

Article in English | MEDLINE | ID: mdl-35264796

9.

Peripheral T cell activation, not thymic selection, expands the T follicular helper repertoire in a lupus-prone murine model.

Lee, Kyungwoo; Park, Juyeon; Tanno, Hidetaka; Georgiou, George; Diamond, Betty; Kim, Sun Jung.

Proc Natl Acad Sci U S A ; 120(48): e2309780120, 2023 Nov 28.

Article in English | MEDLINE | ID: mdl-37983487

10.

High-affinity IgA against microbial glycans.

Lee, Jiwon; Georgiou, George.

Nat Immunol ; 19(6): 514-515, 2018 06.

Article in English | MEDLINE | ID: mdl-29777208

11.

CD8⁺ T cells regulate tumour ferroptosis during cancer immunotherapy.

Wang, Weimin; Green, Michael; Choi, Jae Eun; Gijón, Miguel; Kennedy, Paul D; Johnson, Jeffrey K; Liao, Peng; Lang, Xueting; Kryczek, Ilona; Sell, Amanda; Xia, Houjun; Zhou, Jiajia; Li, Gaopeng; Li, Jing; Li, Wei; Wei, Shuang; Vatan, Linda; Zhang, Hongjuan; Szeliga, Wojciech; Gu, Wei; Liu, Rebecca; Lawrence, Theodore S; Lamb, Candice; Tanno, Yuri; Cieslik, Marcin; Stone, Everett; Georgiou, George; Chan, Timothy A; Chinnaiyan, Arul; Zou, Weiping.

Nature ; 569(7755): 270-274, 2019 05.

Article in English | MEDLINE | ID: mdl-31043744

12.

Leveraging intrinsic flexibility to engineer enhanced enzyme catalytic activity.

Karamitros, Christos S; Murray, Kyle; Winemiller, Brent; Lamb, Candice; Stone, Everett M; D'Arcy, Sheena; Johnson, Kenneth A; Georgiou, George.

Proc Natl Acad Sci U S A ; 119(23): e2118979119, 2022 06 07.

Article in English | MEDLINE | ID: mdl-35658075

13.

Hypersensitivity to ferroptosis in chromophobe RCC is mediated by a glutathione metabolic dependency and cystine import via solute carrier family 7 member 11.

Zhang, Long; Hobeika, Charbel S; Khabibullin, Damir; Yu, Deyang; Filippakis, Harilaos; Alchoueiry, Michel; Tang, Yan; Lam, Hilaire C; Tsvetkov, Peter; Georgiou, George; Lamb, Candice; Stone, Everett; Puigserver, Pere; Priolo, Carmen; Henske, Elizabeth P.

Proc Natl Acad Sci U S A ; 119(28): e2122840119, 2022 07 12.

Article in English | MEDLINE | ID: mdl-35867762

14.

Corrigendum: IgG Fc domains that bind C1q but not effector FcÎ³ receptors delineate the importance of complement-mediated effector functions.

Lee, Chang-Han; Romain, Gabrielle; Yan, Wupeng; Watanabe, Makiko; Charab, Wissam; Todorova, Biliana; Lee, Jiwon; Triplett, Kendra; Donkor, Moses; Lungu, Oana I; Lux, Anja; Marshall, Nicholas; Lindorfer, Margaret A; Goff, Odile Richard-Le; Balbino, Bianca; Kang, Tae Hyun; Tanno, Hidetaka; Delidakis, George; Alford, Corrine; Taylor, Ronald P; Nimmerjahn, Falk; Varadarajan, Navin; Bruhns, Pierre; Zhang, Yan Jessie; Georgiou, George.

Nat Immunol ; 18(10): 1173, 2017 09 19.

Article in English | MEDLINE | ID: mdl-28926542

15.

Enzymatic depletion of l-Met using an engineered human enzyme as a novel therapeutic strategy for melanoma.

Wilder, Carly S; Chiou, Jennifer; Battenhouse, Anna; Saha, Achinto; Chen, Zhao; Kim, Eunice; Gadallah, Mohamed I; Tiziani, Stefano; Georgiou, George; Stone, Everett; DiGiovanni, John.

Mol Carcinog ; 62(10): 1531-1545, 2023 10.

Article in English | MEDLINE | ID: mdl-37378415

16.

Improving Antibody Therapeutics by Manipulating the Fc Domain: Immunological and Structural Considerations.

Delidakis, George; Kim, Jin Eyun; George, Katia; Georgiou, George.

Annu Rev Biomed Eng ; 24: 249-274, 2022 06 06.

Article in English | MEDLINE | ID: mdl-35363537

17.

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

Pataskar, Abhijeet; Champagne, Julien; Nagel, Remco; Kenski, Juliana; Laos, Maarja; Michaux, Justine; Pak, Hui Song; Bleijerveld, Onno B; Mordente, Kelly; Navarro, Jasmine Montenegro; Blommaert, Naomi; Nielsen, Morten M; Lovecchio, Domenica; Stone, Everett; Georgiou, George; de Gooijer, Mark C; van Tellingen, Olaf; Altelaar, Maarten; Joosten, Robbie P; Perrakis, Anastassis; Olweus, Johanna; Bassani-Sternberg, Michal; Peeper, Daniel S; Agami, Reuven.

Nature ; 608(7922): E20, 2022 Aug.

Article in English | MEDLINE | ID: mdl-35840685

18.

Serial and discrete naming and reading in Chinese first graders: Testing predictions from the cascaded processing hypothesis.

Georgiou, George K; Tao, Sha; Romero, Sandra; Ma, Leilei; Chen, Rui; Li, Yuanyuan; Liu, Ningyu; Wang, Lei; Protopapas, Athanassios.

J Exp Child Psychol ; 231: 105650, 2023 07.

Article in English | MEDLINE | ID: mdl-36806750

19.

Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity.

Lu, Wei-Cheng; Saha, Achinto; Yan, Wupeng; Garrison, Kendra; Lamb, Candice; Pandey, Renu; Irani, Seema; Lodi, Alessia; Lu, Xiyuan; Tiziani, Stefano; Zhang, Yan Jessie; Georgiou, George; DiGiovanni, John; Stone, Everett.

Proc Natl Acad Sci U S A ; 117(23): 13000-13011, 2020 06 09.

Article in English | MEDLINE | ID: mdl-32434918

20.

Determinants governing T cell receptor α/ß-chain pairing in repertoire formation of identical twins.

Tanno, Hidetaka; Gould, Timothy M; McDaniel, Jonathan R; Cao, Wenqiang; Tanno, Yuri; Durrett, Russell E; Park, Daechan; Cate, Steven J; Hildebrand, William H; Dekker, Cornelia L; Tian, Lu; Weyand, Cornelia M; Georgiou, George; Goronzy, Jörg J.

Proc Natl Acad Sci U S A ; 117(1): 532-540, 2020 01 07.

Article in English | MEDLINE | ID: mdl-31879353

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