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1.

Neoadjuvant-Adjuvant or Adjuvant-Only Pembrolizumab in Advanced Melanoma.

Patel, Sapna P; Othus, Megan; Chen, Yuanbin; Wright, G Paul; Yost, Kathleen J; Hyngstrom, John R; Hu-Lieskovan, Siwen; Lao, Christopher D; Fecher, Leslie A; Truong, Thach-Giao; Eisenstein, Jennifer L; Chandra, Sunandana; Sosman, Jeffrey A; Kendra, Kari L; Wu, Richard C; Devoe, Craig E; Deutsch, Gary B; Hegde, Aparna; Khalil, Maya; Mangla, Ankit; Reese, Amy M; Ross, Merrick I; Poklepovic, Andrew S; Phan, Giao Q; Onitilo, Adedayo A; Yasar, Demet G; Powers, Benjamin C; Doolittle, Gary C; In, Gino K; Kokot, Niels; Gibney, Geoffrey T; Atkins, Michael B; Shaheen, Montaser; Warneke, James A; Ikeguchi, Alexandra; Najera, Jose E; Chmielowski, Bartosz; Crompton, Joseph G; Floyd, Justin D; Hsueh, Eddy; Margolin, Kim A; Chow, Warren A; Grossmann, Kenneth F; Dietrich, Eliana; Prieto, Victor G; Lowe, Michael C; Buchbinder, Elizabeth I; Kirkwood, John M; Korde, Larissa; Moon, James.

N Engl J Med ; 388(9): 813-823, 2023 Mar 02.

Article in English | MEDLINE | ID: mdl-36856617

2.

The current state of molecular testing in the treatment of patients with solid tumors, 2019.

El-Deiry, Wafik S; Goldberg, Richard M; Lenz, Heinz-Josef; Shields, Anthony F; Gibney, Geoffrey T; Tan, Antoinette R; Brown, Jubilee; Eisenberg, Burton; Heath, Elisabeth I; Phuphanich, Surasak; Kim, Edward; Brenner, Andrew J; Marshall, John L.

CA Cancer J Clin ; 69(4): 305-343, 2019 07.

Article in English | MEDLINE | ID: mdl-31116423

3.

Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study.

Weber, Jeffrey S; Carlino, Matteo S; Khattak, Adnan; Meniawy, Tarek; Ansstas, George; Taylor, Matthew H; Kim, Kevin B; McKean, Meredith; Long, Georgina V; Sullivan, Ryan J; Faries, Mark; Tran, Thuy T; Cowey, C Lance; Pecora, Andrew; Shaheen, Montaser; Segar, Jennifer; Medina, Theresa; Atkinson, Victoria; Gibney, Geoffrey T; Luke, Jason J; Thomas, Sajeve; Buchbinder, Elizabeth I; Healy, Jane A; Huang, Mo; Morrissey, Manju; Feldman, Igor; Sehgal, Vasudha; Robert-Tissot, Celine; Hou, Peijie; Zhu, Lili; Brown, Michelle; Aanur, Praveen; Meehan, Robert S; Zaks, Tal.

Lancet ; 403(10427): 632-644, 2024 Feb 17.

Article in English | MEDLINE | ID: mdl-38246194

4.

A Multicenter Analysis of Immune Checkpoint Inhibitors as Adjuvant Therapy Following Treatment of Isolated Brain Metastasis.

Randall Patrinely, J; Funck-Brentano, Elisa; Nguyen, Khang; Rapisuwon, Suthee; Salem, Joe-Elie; Gibney, Geoffrey T; Carlino, Matteo; Johnson, Douglas B.

Oncologist ; 26(3): e505-e507, 2021 03.

Article in English | MEDLINE | ID: mdl-33225544

5.

Improved survival of patients with melanoma brain metastases in the era of targeted BRAF and immune checkpoint therapies.

Sloot, Sarah; Chen, Yian A; Zhao, Xiuhua; Weber, Jamie L; Benedict, Jacob J; Mulé, James J; Smalley, Keiran S; Weber, Jeffrey S; Zager, Jonathan S; Forsyth, Peter A; Sondak, Vernon K; Gibney, Geoffrey T.

Cancer ; 124(2): 297-305, 2018 01 15.

Article in English | MEDLINE | ID: mdl-29023643

6.

Predictive biomarkers for checkpoint inhibitor-based immunotherapy.

Gibney, Geoffrey T; Weiner, Louis M; Atkins, Michael B.

Lancet Oncol ; 17(12): e542-e551, 2016 Dec.

Article in English | MEDLINE | ID: mdl-27924752

7.

Advances in immunotherapy for melanoma.

Redman, Jason M; Gibney, Geoffrey T; Atkins, Michael B.

BMC Med ; 14: 20, 2016 Feb 06.

Article in English | MEDLINE | ID: mdl-26850630

8.

Evaluating melanoma drug response and therapeutic escape with quantitative proteomics.

Rebecca, Vito W; Wood, Elizabeth; Fedorenko, Inna V; Paraiso, Kim H T; Haarberg, H Eirik; Chen, Yi; Xiang, Yun; Sarnaik, Amod; Gibney, Geoffrey T; Sondak, Vernon K; Koomen, John M; Smalley, Keiran S M.

Mol Cell Proteomics ; 13(7): 1844-54, 2014 Jul.

Article in English | MEDLINE | ID: mdl-24760959

9.

Phosphoproteomic analysis of basal and therapy-induced adaptive signaling networks in BRAF and NRAS mutant melanoma.

Fedorenko, Inna V; Fang, Bin; Munko, Ana Cecelia; Gibney, Geoffrey T; Koomen, John M; Smalley, Keiran S M.

Proteomics ; 15(2-3): 327-39, 2015 Jan.

Article in English | MEDLINE | ID: mdl-25339196

10.

p75 neurotrophin receptor cleavage by α- and Î³-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.

Forsyth, Peter A; Krishna, Niveditha; Lawn, Samuel; Valadez, J Gerardo; Qu, Xiaotao; Fenstermacher, David A; Fournier, Michelle; Potthast, Lisa; Chinnaiyan, Prakash; Gibney, Geoffrey T; Zeinieh, Michele; Barker, Philip A; Carter, Bruce D; Cooper, Michael K; Kenchappa, Rajappa S.

J Biol Chem ; 289(12): 8067-85, 2014 Mar 21.

Article in English | MEDLINE | ID: mdl-24519935

11.

LINAC-based stereotactic radiosurgery to the brain with concurrent vemurafenib for melanoma metastases.

Ahmed, Kamran A; Freilich, Jessica M; Sloot, Sarah; Figura, Nicholas; Gibney, Geoffrey T; Weber, Jeffrey S; Sarangkasiri, Siriporn; Chinnaiyan, Prakash; Forsyth, Peter A; Etame, Arnold B; Rao, Nikhil G.

J Neurooncol ; 122(1): 121-6, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25519302

12.

Immunotherapy or molecularly targeted therapy: what is the best initial treatment for stage IV BRAF-mutant melanoma?

Gibney, Geoffrey T; Atkins, Michael B.

Clin Adv Hematol Oncol ; 13(7): 451-8, 2015 Jul.

Article in English | MEDLINE | ID: mdl-26353041

13.

Choice of first-line therapy in metastatic melanoma.

Gibney, Geoffrey T; Atkins, Michael B.

Cancer ; 125(5): 666-669, 2019 03 01.

Article in English | MEDLINE | ID: mdl-30695110

14.

Reply to Improving the survival of patients with American Joint Committee on Cancer stage III and IV melanoma.

Sloot, Sarah; Chen, Yian A; Zhao, Xiuhua; Weber, Jamie L; Benedict, Jacob J; Mulé, James J; Smalley, Keiran S; Weber, Jeffrey S; Zager, Jonathan S; Forsyth, Peter A; Sondak, Vernon K; Gibney, Geoffrey T.

Cancer ; 124(10): 2254-2255, 2018 05 15.

Article in English | MEDLINE | ID: mdl-29543319

15.

Novel treatments for melanoma brain metastases.

Kenchappa, Rajappa S; Tran, Nam; Rao, Nikhil G; Smalley, Keiran S; Gibney, Geoffrey T; Sondak, Vernon K; Forsyth, Peter A.

Cancer Control ; 20(4): 298-306, 2013 Oct.

Article in English | MEDLINE | ID: mdl-24077406

16.

Combination of Itacitinib or Parsaclisib with Pembrolizumab in Patients with Advanced Solid Tumors: A Phase I Study.

Munster, Pamela; Iannotti, Nicholas; Cho, Daniel C; Kirkwood, John M; Villaruz, Liza C; Gibney, Geoffrey T; Hodi, F Stephen; Mettu, Niharika B; Jones, Mark; Bowman, Jill; Smith, Michael; Lakshminarayanan, Mani; O'Day, Steven.

Cancer Res Commun ; 3(12): 2572-2584, 2023 12 19.

Article in English | MEDLINE | ID: mdl-38115208

17.

Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases.

In, Gino K; Ribeiro, Jennifer R; Yin, Jun; Xiu, Joanne; Bustos, Matias A; Ito, Fumito; Chow, Frances; Zada, Gabriel; Hwang, Lindsay; Salama, April K S; Park, Soo J; Moser, Justin C; Darabi, Sourat; Domingo-Musibay, Evidio; Ascierto, Maria L; Margolin, Kim; Lutzky, Jose; Gibney, Geoffrey T; Atkins, Michael B; Izar, Benjamin; Hoon, Dave S B; VanderWalde, Ari M.

NPJ Precis Oncol ; 7(1): 120, 2023 Nov 14.

Article in English | MEDLINE | ID: mdl-37964004

18.

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of melanoma, version 3.0.

Pavlick, Anna C; Ariyan, Charlotte E; Buchbinder, Elizabeth I; Davar, Diwakar; Gibney, Geoffrey T; Hamid, Omid; Hieken, Tina J; Izar, Benjamin; Johnson, Douglas B; Kulkarni, Rajan P; Luke, Jason J; Mitchell, Tara C; Mooradian, Meghan J; Rubin, Krista M; Salama, April Ks; Shirai, Keisuke; Taube, Janis M; Tawbi, Hussein A; Tolley, J Keith; Valdueza, Caressa; Weiss, Sarah A; Wong, Michael K; Sullivan, Ryan J.

J Immunother Cancer ; 11(10)2023 10.

Article in English | MEDLINE | ID: mdl-37852736

19.

Transcriptional Profiling of Malignant Melanoma Reveals Novel and Potentially Targetable Gene Fusions.

Darabi, Sourat; Elliott, Andrew; Braxton, David R; Zeng, Jia; Hodges, Kurt; Poorman, Kelsey; Swensen, Jeff; Shanthappa, Basavaraja U; Hinton, James P; Gibney, Geoffrey T; Moser, Justin; Phung, Thuy; Atkins, Michael B; In, Gino K; Korn, Wolfgang M; Eisenberg, Burton L; Demeure, Michael J.

Cancers (Basel) ; 14(6)2022 Mar 15.

Article in English | MEDLINE | ID: mdl-35326655

20.

First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab: ICOS-High CD4 T-Cell Populations and Predictors of Response.

Yap, Timothy A; Gainor, Justin F; Callahan, Margaret K; Falchook, Gerald S; Pachynski, Russell K; LoRusso, Patricia; Kummar, Shivaani; Gibney, Geoffrey T; Burris, Howard A; Tykodi, Scott S; Rahma, Osama E; Seiwert, Tanguy Y; Papadopoulos, Kyriakos P; Blum Murphy, Mariela; Park, Haeseong; Hanson, Amanda; Hashambhoy-Ramsay, Yasmin; McGrath, Lara; Hooper, Ellen; Xiao, Xiaoying; Cohen, Heather; Fan, Martin; Felitsky, Daniel; Hart, Courtney; McComb, Rachel; Brown, Karen; Sepahi, Ali; Jimenez, Judith; Zhang, Weidong; Baeck, Johan; Laken, Haley; Murray, Richard; Trehu, Elizabeth; Harvey, Christopher J.

Clin Cancer Res ; 28(17): 3695-3708, 2022 09 01.

Article in English | MEDLINE | ID: mdl-35511938

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