ABSTRACT
The annual incidence of clinically apparent cirrhosis of the liver from all causes in the islands of Lewis and Harris has been found to be 5.5 cases per 100,000 and alcoholic cirrhosis to be 2.76 per 100,000. Sales of alcohol in the island amount to 6.85 million pounds giving a per capita spending on alcohol of 283 pounds in 1984. The incidence of alcoholic cardiomyopathy was found to be 3.7 cases per 100,000 and there were 120 admissions per 100,000 with illnesses directly related to alcoholism. It was suggested that the very low incidence of alcoholic cirrhosis despite the high per capita spending on alcohol could be due to inherited factors, the pattern of drinking and the type of alcohol consumed.
Subject(s)
Liver Cirrhosis, Alcoholic/epidemiology , Adult , Aged , Female , Hebrides , Humans , Male , Middle AgedABSTRACT
Twenty-five patients suffering from gross refractory obesity agreed to be starved in hospital until they weighed not more than 25% over their ideal weight. Two discharged themselves prematurely, four defaulted from follow-up, and seven who for various reasons were discharged before completing their treatment have since regained weight. After a mean follow-up period of nearly 18 months 8 of the remaining 12 remained near their weight on discharge. Some kind of initial psychological assessment might improve these results, but prolonged therapeutic starvation may be of value in young patients with gross refractory obesity who are psychologically suitable and socially able to undergo such treatment.
Subject(s)
Fasting , Obesity/therapy , Adolescent , Adult , Body Weight , Female , Follow-Up Studies , Hospitalization , Humans , Male , Middle Aged , Psychological TestsABSTRACT
Fifty patients suffering from infections caused by various salmonella species were treated with trimethoprim-sulphamethoxazole compound. Twenty-three had enteric fever and two were biliary carriers of Salmonella typhi. The other 25 suffered from infections caused by salmonella species other than S. typhi or S. paratyphi B. Twenty-one of the patients with enteric fever responded clinically to the drug, one failed treatment, and one died. Two patients suffering from typhoid fever relapsed and three temporarily excreted S. typhi in stools following treatment. One of the typhoid carriers was successfully treated. All patients with infections caused by salmonella species other than S. typhi or S. paratyphi B responded to treatment but 17 continued to excrete the organism in their stools after the course of trimethoprim-sulphamethoxazole compound. Four patients developed rashes during therapy and two became anaemic.