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1.
BMC Med Educ ; 24(1): 644, 2024 Jun 07.
Article in English | MEDLINE | ID: mdl-38849847

ABSTRACT

BACKGROUND: The rapid growth of artificial intelligence (AI) technologies has been driven by the latest advances in computing power. Although, there exists a dearth of research on the application of AI in medical education. METHODS: this study is based on the TAM-ISSM-UTAUT model and introduces STARA awareness and chilling effect as moderating variables. A total of 657 valid questionnaires were collected from students of a medical university in Dalian, China, and data were statistically described using SPSS version 26, Amos 3.0 software was used to validate the research model, as well as moderated effects analysis using Process (3.3.1) software, and Origin (2021) software. RESULTS: The findings reveal that both information quality and perceived usefulness are pivotal factors that positively influence the willingness to use AI products. It also uncovers the moderating influence of the chilling effect and STARA awareness. CONCLUSIONS: This suggests that enhancing information quality can be a key strategy to encourage the widespread use of AI products. Furthermore, this investigation offers valuable insights into the intersection of medical education and AI use from the standpoint of medical students. This research may prove to be pertinent in shaping the promotion of Medical Education Intelligence in the future.


Subject(s)
Artificial Intelligence , Education, Medical , Students, Medical , Humans , Students, Medical/psychology , Surveys and Questionnaires , Male , Female , China , Young Adult , Awareness
2.
J Agric Food Chem ; 56(24): 12059-63, 2008 Dec 24.
Article in English | MEDLINE | ID: mdl-19012407

ABSTRACT

Acrylamide (AA), a proven rodent carcinogen, has recently been discovered in foods heated at high temperatures. This finding raises public health concerns. In our previous study, we found that AA caused DNA fragments and increase of reactive oxygen species (ROS) formation and induced genotoxicity and weak cytotoxicity in HepG2 cells. Presently, curcumin, a natural antioxidant compound present in turmeric was evaluated for its protective effects. The results showed that curcumin at the concentration of 2.5 microg/mL significantly reduced AA-induced ROS production, DNA fragments, micronuclei formation, and cytotoxicity in HepG2 cells. The effect of PEG-catalase on protecting against AA-induced cytotoxicity suggests that AA-induced cytotoxicity is directly dependent on hydrogen peroxide production. These data suggest that curcumin could attenuate the cytotoxicity and genotoxicity induced by AA in HepG2 cells. The protection is probably mediated by an antioxidant protective mechanism. Consumption of curcumin may be a plausible way to prevent AA-mediated genotoxicity.


Subject(s)
Acrylamide/toxicity , Curcuma/chemistry , Curcumin/pharmacology , DNA Damage/drug effects , Free Radical Scavengers/pharmacology , Reactive Oxygen Species/metabolism , Cell Line, Tumor , Cell Survival/drug effects , Comet Assay , Curcumin/chemistry , DNA Fragmentation/drug effects , Free Radical Scavengers/chemistry , Humans , Plant Extracts/chemistry , Plant Extracts/pharmacology
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