ABSTRACT
INTRODUCTION: The burden of HIV is on the rise and patients with HIV are also vulnerable to renal impairment from both acute and chronic causes. This study sets out to evaluate renal care received by such patients. METHODS: The study was conducted at Connaught Hospital, the main tertiary hospital (for medical and surgical cases) in the country. A retrospective review of all admitted patients with HIV between January and December 2019. Data was collected using a well- structured study proforma. RESULTS: A total of 230 patients were admitted with HIV during the study period. The mean age of patients was 36.9 ± (11.5) years with a female preponderance of 61.3%. A vast majority of the patients (54.8%) could afford to do some renal investigations and only 13.9% were seen by renal physicians; 69.1% of patients with azotaemia died while on admission. CONCLUSION: The extent of renal care observed from the study was poor because the majority of the patients were not seen by renal physicians and could not afford renal investigations. Also, the occurrence of renal impairment in patients with HIV suggests a poor prognosis.
INTRODUCTION: Le fardeau du VIH est en augmentation et les patients séropositifs sont également vulnérables à l'insuffisance rénale due à des causes aiguës et chroniques. Cette étude a pour but d'évaluer les soins rénaux reçus par ces patients. MÉTHODES: L'étude a été menée à l'hôpital Connaught, le principal établissement tertiaire (pour les cas médicaux et chirurgicaux) du pays; un examen rétrospectif de tous les patients admis avec le VIH entre janvier et décembre 2019. Les données ont été recueillies à l'aide d'un proforma d'étude bien structuré. RÉSULTATS: Un total de 230 patients ont été admis avec le VIH au cours de la période d'étude. L'âge moyen des patients était de 36,9±(11,5) ans avec une prépondérance féminine de 61,3%. La grande majorité des patients (54,8 %) pouvaient se permettre de faire quelques examens rénaux et seuls 13,9 % ont été vus par des médecins spécialisés dans les maladies rénales; 69,1 % des patients atteints d'azotémie sont décédés pendant leur admission. CONCLUSION: L'étendue des soins rénaux observés dans cette étude est faible car la majorité des patients n'ont pas été vus par des médecins rénaux et ne pouvaient pas se permettre de faire des examens rénaux. De plus, la présence d'une insuffisance rénale chez les patients atteints du VIH suggère un mauvais pronostic. Mots clés: Soins rénaux, patients VIH, Hôpital tertiaire, Sierra Leone.
Subject(s)
HIV Infections , Renal Insufficiency , Humans , Female , Tertiary Care Centers , Sierra Leone , Hospitalization , HIV Infections/complications , HIV Infections/epidemiology , HIVABSTRACT
OBJECTIVE: The purpose of this study was to examine trends in clinical characteristics and in-hospital mortality of HIV patients in a low resource setting in the period 2010 to 2016. METHODS: Data on socio-demographic and clinical characteristics of 313 hospitalized HIV positive patients at the University College Hospital, Ibadan, Nigeria were retrospectively extracted, described and examined for trends. Factors independently associated with mortality were identified using multiple logistic regression. RESULTS: The mean age was 39 years (SD = 9.8) and about two thirds were female. The proportion of females decreased significantly from 83.3% in 2010-2011 to 39.8% in 2016. There was a significant reduction in the diagnosis of disseminated tuberculosis and mortality from 19.4% and 42.9% in 2010-2011 to 4.8% and 27.9% in 2016 respectively. On multiple logistic regression, being male, having neurological features, meningitis, and shorter stay in hospital had significantly higher odds of mortality. CONCLUSION: There was a reduction in in-hospital mortality of HIV patients over the period from 2010 to 2016. Being male and presence of neurological features were associated with mortality. Larger prospective studies are needed to further investigate this observed reduction in mortality among hospitalised patients.