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J Asian Nat Prod Res ; 25(12): 1217-1222, 2023 Dec.
Article in English | MEDLINE | ID: mdl-37163366

ABSTRACT

A new abietane diterpenoid, 1ß, 11-epoxyabieta-12-hydroxy-8, 11, 13-triene-7-one (1), along with three known compounds (2-4), was isolated from Lycopodium complanatum. Their structures were confirmed by the analysis of 1D, 2D NMR and HRESIMS data, and comparison with previous spectral data. All compounds were tested for inhibitory activities against A549, HepG2 and MCF-7 tumor cell lines. [Figure: see text].


Subject(s)
Antineoplastic Agents, Phytogenic , Lycopodium , Humans , Abietanes/pharmacology , Abietanes/chemistry , Molecular Structure , Lycopodium/chemistry , Cell Line, Tumor , MCF-7 Cells , Antineoplastic Agents, Phytogenic/pharmacology , Antineoplastic Agents, Phytogenic/chemistry
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