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1.

Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.

Shen, Min; Siu, Sophia; Byrd, Samantha; Edelmann, Kurt H; Patel, Neha; Ketchem, Randal R; Mehlin, Christopher; Arnett, Heather A; Hasegawa, Haruki.

Exp Cell Res ; 317(7): 976-93, 2011 Apr 15.

Article in English | MEDLINE | ID: mdl-21182835

2.

Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies.

Gopalakrishnapillai, Anilkumar; Correnti, Colin E; Pilat, Kristina; Lin, Ida; Chan, Man Kid; Bandaranayake, Ashok D; Mehlin, Christopher; Kisielewski, Anne; Hamill, Darcy; Kaeding, Allison J; Meshinchi, Soheil; Olson, James M; Kolb, Edward Anders; Barwe, Sonali P.

Cancers (Basel) ; 13(23)2021 Nov 26.

Article in English | MEDLINE | ID: mdl-34885074

3.

A diversity of antibody epitopes can induce signaling through the erythropoietin receptor.

Lim, Ai Ching; Ketchem, Randal R; Borges, Luis; Carabeo, Teresa; Carter, Jane; Hoover, Joseph E; Hu, Zhonghua; Wittekind, Michael; Zhou, Hongxing; Mehlin, Christopher.

Biochemistry ; 49(18): 3797-804, 2010 May 11.

Article in English | MEDLINE | ID: mdl-20337434

4.

A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure.

Cook Sangar, Michelle L; Girard, Emily J; Hopping, Gene; Yin, Chunfeng; Pakiam, Fiona; Brusniak, Mi-Youn; Nguyen, Elizabeth; Ruff, Raymond; Gewe, Mesfin M; Byrnes-Blake, Kelly; Nairn, Natalie W; Miller, Dennis M; Mehlin, Christopher; Strand, Andrew D; Mhyre, Andrew J; Correnti, Colin E; Strong, Roland K; Simon, Julian A; Olson, James M.

Sci Transl Med ; 12(533)2020 03 04.

Article in English | MEDLINE | ID: mdl-32132215

5.

Structural genomics of pathogenic protozoa: an overview.

Fan, Erkang; Baker, David; Fields, Stanley; Gelb, Michael H; Buckner, Frederick S; Van Voorhis, Wesley C; Phizicky, Eric; Dumont, Mark; Mehlin, Christopher; Grayhack, Elizabeth; Sullivan, Mark; Verlinde, Christophe; Detitta, George; Meldrum, Deirdre R; Merritt, Ethan A; Earnest, Thomas; Soltis, Michael; Zucker, Frank; Myler, Peter J; Schoenfeld, Lori; Kim, David; Worthey, Liz; Lacount, Doug; Vignali, Marissa; Li, Jizhen; Mondal, Somnath; Massey, Archna; Carroll, Brian; Gulde, Stacey; Luft, Joseph; Desoto, Larry; Holl, Mark; Caruthers, Jonathan; Bosch, Jürgen; Robien, Mark; Arakaki, Tracy; Holmes, Margaret; Le Trong, Isolde; Hol, Wim G J.

Methods Mol Biol ; 426: 497-513, 2008.

Article in English | MEDLINE | ID: mdl-18542886

6.

Screening, large-scale production and structure-based classification of cystine-dense peptides.

Correnti, Colin E; Gewe, Mesfin M; Mehlin, Christopher; Bandaranayake, Ashok D; Johnsen, William A; Rupert, Peter B; Brusniak, Mi-Youn; Clarke, Midori; Burke, Skyler E; De Van Der Schueren, Willem; Pilat, Kristina; Turnbaugh, Shanon M; May, Damon; Watson, Alex; Chan, Man Kid; Bahl, Christopher D; Olson, James M; Strong, Roland K.

Nat Struct Mol Biol ; 25(3): 270-278, 2018 03.

Article in English | MEDLINE | ID: mdl-29483648

7.

Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site.

Robien, Mark A; Bosch, Jürgen; Buckner, Frederick S; Van Voorhis, Wesley C E; Worthey, Elizabeth A; Myler, Peter; Mehlin, Christopher; Boni, Erica E; Kalyuzhniy, Oleksandr; Anderson, Lori; Lauricella, Angela; Gulde, Stacy; Luft, Joseph R; DeTitta, George; Caruthers, Jonathan M; Hodgson, Keith O; Soltis, Michael; Zucker, Frank; Verlinde, Christophe L M J; Merritt, Ethan A; Schoenfeld, Lori W; Hol, Wim G J.

Proteins ; 62(3): 570-7, 2006 Mar 15.

Article in English | MEDLINE | ID: mdl-16345073

8.

Heterologous expression of proteins from Plasmodium falciparum: results from 1000 genes.

Mehlin, Christopher; Boni, Erica; Buckner, Frederick S; Engel, Linnea; Feist, Tiffany; Gelb, Michael H; Haji, Lutfiyah; Kim, David; Liu, Colleen; Mueller, Natascha; Myler, Peter J; Reddy, J T; Sampson, Joshua N; Subramanian, E; Van Voorhis, Wesley C; Worthey, Elizabeth; Zucker, Frank; Hol, Wim G J.

Mol Biochem Parasitol ; 148(2): 144-60, 2006 Aug.

Article in English | MEDLINE | ID: mdl-16644028

9.

Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.

Bosch, Jürgen; Robien, Mark A; Mehlin, Christopher; Boni, Erica; Riechers, Aaron; Buckner, Frederick S; Van Voorhis, Wesley C; Myler, Peter J; Worthey, Elizabeth A; DeTitta, George; Luft, Joseph R; Lauricella, Angela; Gulde, Stacey; Anderson, Lori A; Kalyuzhniy, Oleksandr; Neely, Helen M; Ross, Jenni; Earnest, Thomas N; Soltis, Michael; Schoenfeld, Lori; Zucker, Frank; Merritt, Ethan A; Fan, Erkang; Verlinde, Christophe L M J; Hol, Wim G J.

J Med Chem ; 49(20): 5939-46, 2006 Oct 05.

Article in English | MEDLINE | ID: mdl-17004709

10.

Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.

Holmes, Margaret A; Buckner, Frederick S; Van Voorhis, Wesley C; Verlinde, Christophe L M J; Mehlin, Christopher; Boni, Erica; DeTitta, George; Luft, Joseph; Lauricella, Angela; Anderson, Lori; Kalyuzhniy, Oleksandr; Zucker, Frank; Schoenfeld, Lori W; Earnest, Thomas N; Hol, Wim G J; Merritt, Ethan A.

Acta Crystallogr Sect F Struct Biol Cryst Commun ; 62(Pt 5): 427-31, 2006 May 01.

Article in English | MEDLINE | ID: mdl-16682767

11.

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.

Holmes, Margaret A; Buckner, Frederick S; Van Voorhis, Wesley C; Mehlin, Christopher; Boni, Erica; Earnest, Thomas N; DeTitta, George; Luft, Joseph; Lauricella, Angela; Anderson, Lori; Kalyuzhniy, Oleksandr; Zucker, Frank; Schoenfeld, Lori W; Hol, Wim G J; Merritt, Ethan A.

Acta Crystallogr Sect F Struct Biol Cryst Commun ; 62(Pt 3): 180-5, 2006 Mar 01.

Article in English | MEDLINE | ID: mdl-16511296

12.

Structure-based drug discovery for Plasmodium falciparum.

Mehlin, Christopher.

Comb Chem High Throughput Screen ; 8(1): 5-14, 2005 Feb.

Article in English | MEDLINE | ID: mdl-15720193

13.

Simultaneous multiple interaction T-cell engaging (SMITE) bispecific antibodies overcome bispecific T-cell engager (BiTE) resistance via CD28 co-stimulation.

Correnti, Colin E; Laszlo, George S; de van der Schueren, Willem J; Godwin, Colin D; Bandaranayake, Ashok; Busch, Melanie A; Gudgeon, Chelsea J; Bates, Olivia M; Olson, James M; Mehlin, Christopher; Walter, Roland B.

Leukemia ; 32(5): 1239-1243, 2018 05.

Article in English | MEDLINE | ID: mdl-29588544

14.

Fusion partners as a tool for the expression of difficult proteins in mammalian cells.

Zhang, Jue; Carter, Jane; Siu, Sophia; O'Neill, Jason W; Gates, Andrew H; Delaney, John; Mehlin, Christopher.

Curr Pharm Biotechnol ; 11(3): 241-5, 2010 Apr.

Article in English | MEDLINE | ID: mdl-20210749

15.

Fusion partners can increase the expression of recombinant interleukins via transient transfection in 2936E cells.

Carter, Jane; Zhang, Jue; Dang, Thien-Lan; Hasegawa, Haruki; Cheng, Janet D; Gianan, Irene; O'Neill, Jason W; Wolfson, Martin; Siu, Sophia; Qu, Sheldon; Meininger, David; Kim, Helen; Delaney, John; Mehlin, Christopher.

Protein Sci ; 19(2): 357-62, 2010 Feb.

Article in English | MEDLINE | ID: mdl-20014434

16.

No-wash dyes for calcium flux measurement.

Mehlin, Christopher; Crittenden, Carole; Andreyka, Jamie.

Biotechniques ; 34(1): 164-6, 2003 Jan.

Article in English | MEDLINE | ID: mdl-12545554

17.

Measurement of VLA-4/CS-1 and VLA-4/VCAM adhesion inhibition.

Mehlin, Christopher.

Curr Protoc Pharmacol ; Chapter 12: Unit 12.7, 2004 May 01.

Article in English | MEDLINE | ID: mdl-22294119

18.

Cloning grills: high throughput cloning for structural genomics.

Mehlin, Christopher; Boni, Erica E; Andreyka, Jamie; Terry, Richard W.

J Struct Funct Genomics ; 5(1-2): 59-61, 2004.

Article in English | MEDLINE | ID: mdl-15263843

19.

Sulphonamide-based small molecule VLA-4 antagonists.

Stasiak, Marcin; Mehlin, Christopher; Boni, Erica; Vaisar, Tomas; Little, Thomas; Kim, Hwa-Ok; Qabar, Maher.

Bioorg Med Chem Lett ; 13(21): 3875-8, 2003 Nov 03.

Article in English | MEDLINE | ID: mdl-14552799

20.

An improved protocol for rapid freezing of protein samples for long-term storage.

Deng, Junpeng; Davies, Douglas R; Wisedchaisri, Goragot; Wu, Meiting; Hol, Wim G J; Mehlin, Christopher.

Acta Crystallogr D Biol Crystallogr ; 60(Pt 1): 203-4, 2004 Jan.

Article in English | MEDLINE | ID: mdl-14684931

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