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J Assoc Physicians India ; 65(11): 92-93, 2017 Nov.
Article in English | MEDLINE | ID: mdl-29322720

ABSTRACT

A 19 year female, presented with life threatening haemoptysis and cough with minimum expectoration for 3 months. Bronchoscopy showed multiple nodules in airway. The direct microscopy and culture of sputum revealed fungal elements and Aspergillus flavus respectively. Serum Galactomannan was positive. Thus diagnosis of invasive aspergillus tracheo-bronchitis made. She responded to voriconazole. Aspergillus tracheo-bronchitis is a rare form of invasive pulmonary aspergillosis in immuno-competent host. Aspergillus spp in respiratory samples should not be routinely discarded as colonization.


Subject(s)
Aspergillus , Bronchitis/microbiology , Hemoptysis , Invasive Pulmonary Aspergillosis , Sputum/microbiology , Tracheitis/microbiology , Voriconazole/administration & dosage , Airway Obstruction/diagnosis , Airway Obstruction/etiology , Antifungal Agents/administration & dosage , Aspergillus/isolation & purification , Aspergillus/physiology , Bronchitis/physiopathology , Bronchitis/therapy , Bronchoscopy/methods , Female , Galactose/analogs & derivatives , Hemoptysis/diagnosis , Hemoptysis/etiology , Hemoptysis/physiopathology , Hemoptysis/therapy , Humans , Invasive Pulmonary Aspergillosis/complications , Invasive Pulmonary Aspergillosis/diagnosis , Invasive Pulmonary Aspergillosis/drug therapy , Invasive Pulmonary Aspergillosis/physiopathology , Mannans/analysis , Mannans/blood , Tracheitis/physiopathology , Tracheitis/therapy , Treatment Outcome , Young Adult
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