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1.

Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.

Bayerl, Felix; Meiser, Philippa; Donakonda, Sainitin; Hirschberger, Anna; Lacher, Sebastian B; Pedde, Anna-Marie; Hermann, Chris D; Elewaut, Anais; Knolle, Moritz; Ramsauer, Lukas; Rudolph, Thomas J; Grassmann, Simon; Öllinger, Rupert; Kirchhammer, Nicole; Trefny, Marcel; Anton, Martina; Wohlleber, Dirk; Höchst, Bastian; Zaremba, Anne; Krüger, Achim; Rad, Roland; Obenauf, Anna C; Schadendorf, Dirk; Zippelius, Alfred; Buchholz, Veit R; Schraml, Barbara U; Böttcher, Jan P.

Immunity ; 56(6): 1341-1358.e11, 2023 06 13.

Article in English | MEDLINE | ID: mdl-37315536

2.

Serpins promote cancer cell survival and vascular co-option in brain metastasis.

Valiente, Manuel; Obenauf, Anna C; Jin, Xin; Chen, Qing; Zhang, Xiang H-F; Lee, Derek J; Chaft, Jamie E; Kris, Mark G; Huse, Jason T; Brogi, Edi; Massagué, Joan.

Cell ; 156(5): 1002-16, 2014 Feb 27.

Article in English | MEDLINE | ID: mdl-24581498

3.

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability.

Mlecnik, Bernhard; Bindea, Gabriela; Angell, Helen K; Maby, Pauline; Angelova, Mihaela; Tougeron, David; Church, Sarah E; Lafontaine, Lucie; Fischer, Maria; Fredriksen, Tessa; Sasso, Maristella; Bilocq, Amélie M; Kirilovsky, Amos; Obenauf, Anna C; Hamieh, Mohamad; Berger, Anne; Bruneval, Patrick; Tuech, Jean-Jacques; Sabourin, Jean-Christophe; Le Pessot, Florence; Mauillon, Jacques; Rafii, Arash; Laurent-Puig, Pierre; Speicher, Michael R; Trajanoski, Zlatko; Michel, Pierre; Sesboüe, Richard; Frebourg, Thierry; Pagès, Franck; Valge-Archer, Viia; Latouche, Jean-Baptiste; Galon, Jérôme.

Immunity ; 44(3): 698-711, 2016 Mar 15.

Article in English | MEDLINE | ID: mdl-26982367

4.

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

Bindea, Gabriela; Mlecnik, Bernhard; Tosolini, Marie; Kirilovsky, Amos; Waldner, Maximilian; Obenauf, Anna C; Angell, Helen; Fredriksen, Tessa; Lafontaine, Lucie; Berger, Anne; Bruneval, Patrick; Fridman, Wolf Herman; Becker, Christoph; Pagès, Franck; Speicher, Michael R; Trajanoski, Zlatko; Galon, Jérôme.

Immunity ; 39(4): 782-95, 2013 Oct 17.

Article in English | MEDLINE | ID: mdl-24138885

5.

Metastatic colonization by circulating tumour cells.

Massagué, Joan; Obenauf, Anna C.

Nature ; 529(7586): 298-306, 2016 Jan 21.

Article in English | MEDLINE | ID: mdl-26791720

6.

Therapy-induced tumour secretomes promote resistance and tumour progression.

Obenauf, Anna C; Zou, Yilong; Ji, Andrew L; Vanharanta, Sakari; Shu, Weiping; Shi, Hubing; Kong, Xiangju; Bosenberg, Marcus C; Wiesner, Thomas; Rosen, Neal; Lo, Roger S; Massagué, Joan.

Nature ; 520(7547): 368-72, 2015 Apr 16.

Article in English | MEDLINE | ID: mdl-25807485

7.

Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.

Wiesner, Thomas; Lee, William; Obenauf, Anna C; Ran, Leili; Murali, Rajmohan; Zhang, Qi Fan; Wong, Elissa W P; Hu, Wenhuo; Scott, Sasinya N; Shah, Ronak H; Landa, Iñigo; Button, Julia; Lailler, Nathalie; Sboner, Andrea; Gao, Dong; Murphy, Devan A; Cao, Zhen; Shukla, Shipra; Hollmann, Travis J; Wang, Lu; Borsu, Laetitia; Merghoub, Taha; Schwartz, Gary K; Postow, Michael A; Ariyan, Charlotte E; Fagin, James A; Zheng, Deyou; Ladanyi, Marc; Busam, Klaus J; Berger, Michael F; Chen, Yu; Chi, Ping.

Nature ; 526(7573): 453-7, 2015 Oct 15.

Article in English | MEDLINE | ID: mdl-26444240

8.

Cancer Evolution: A Multifaceted Affair.

Ciriello, Giovanni; Magnani, Luca; Aitken, Sarah J; Akkari, Leila; Behjati, Sam; Hanahan, Douglas; Landau, Dan A; Lopez-Bigas, Nuria; Lupiáñez, Darío G; Marine, Jean-Christophe; Martin-Villalba, Ana; Natoli, Gioacchino; Obenauf, Anna C; Oricchio, Elisa; Scaffidi, Paola; Sottoriva, Andrea; Swarbrick, Alexander; Tonon, Giovanni; Vanharanta, Sakari; Zuber, Johannes.

Cancer Discov ; 14(1): 36-48, 2024 01 12.

Article in English | MEDLINE | ID: mdl-38047596

9.

Mutations in GNA11 in uveal melanoma.

Van Raamsdonk, Catherine D; Griewank, Klaus G; Crosby, Michelle B; Garrido, Maria C; Vemula, Swapna; Wiesner, Thomas; Obenauf, Anna C; Wackernagel, Werner; Green, Gary; Bouvier, Nancy; Sozen, M Mert; Baimukanova, Gail; Roy, Ritu; Heguy, Adriana; Dolgalev, Igor; Khanin, Raya; Busam, Klaus; Speicher, Michael R; O'Brien, Joan; Bastian, Boris C.

N Engl J Med ; 363(23): 2191-9, 2010 Dec 02.

Article in English | MEDLINE | ID: mdl-21083380

10.

Disruption of Trp53 in livers of mice induces formation of carcinomas with bilineal differentiation.

Katz, Sarah-Fee; Lechel, André; Obenauf, Anna C; Begus-Nahrmann, Yvonne; Kraus, Johann M; Hoffmann, Eva M; Duda, Johanna; Eshraghi, Parisa; Hartmann, Daniel; Liss, Birgit; Schirmacher, Peter; Kestler, Hans A; Speicher, Michael R; Rudolph, K Lenhard.

Gastroenterology ; 142(5): 1229-1239.e3, 2012 May.

Article in English | MEDLINE | ID: mdl-22342966

11.

Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell-like Program Conserved in HPV-Positive Cancers.

Leiendecker, Lukas; Neumann, Tobias; Jung, Pauline S; Cronin, Shona M; Steinacker, Thomas L; Schleiffer, Alexander; Schutzbier, Michael; Mechtler, Karl; Kervarrec, Thibault; Laurent, Estelle; Bachiri, Kamel; Coyaud, Etienne; Murali, Rajmohan; Busam, Klaus J; Itzinger-Monshi, Babak; Kirnbauer, Reinhard; Cerroni, Lorenzo; Calonje, Eduardo; Rütten, Arno; Stubenrauch, Frank; Griewank, Klaus G; Wiesner, Thomas; Obenauf, Anna C.

Cancer Discov ; 13(1): 70-84, 2023 01 09.

Article in English | MEDLINE | ID: mdl-36213965

12.

High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.

Mathiesen, Randi R; Fjelldal, Renathe; Liestøl, Knut; Due, Eldri U; Geigl, Jochen B; Riethdorf, Sabine; Borgen, Elin; Rye, Inga H; Schneider, Ida J; Obenauf, Anna C; Mauermann, Oliver; Nilsen, Gro; Christian Lingjaerde, Ole; Børresen-Dale, Anne-Lise; Pantel, Klaus; Speicher, Michael R; Naume, Bjørn; Baumbusch, Lars O.

Int J Cancer ; 131(4): E405-15, 2012 Aug 15.

Article in English | MEDLINE | ID: mdl-21935921

13.

Rapid identification of homologous recombinants and determination of gene copy number with reference/query pyrosequencing (RQPS).

Liu, Zhenyi; Obenauf, Anna C; Speicher, Michael R; Kopan, Raphael.

Genome Res ; 19(11): 2081-9, 2009 Nov.

Article in English | MEDLINE | ID: mdl-19797679

14.

Mechanism-based combination therapies for metastatic cancer.

Obenauf, Anna C.

Sci Transl Med ; 14(655): eadd0887, 2022 07 27.

Article in English | MEDLINE | ID: mdl-35895833

15.

Defining 'chromosomal instability'.

Geigl, Jochen B; Obenauf, Anna C; Schwarzbraun, Thomas; Speicher, Michael R.

Trends Genet ; 24(2): 64-9, 2008 Feb.

Article in English | MEDLINE | ID: mdl-18192061

16.

Humanized large-scale expanded endothelial colony-forming cells function in vitro and in vivo.

Reinisch, Andreas; Hofmann, Nicole A; Obenauf, Anna C; Kashofer, Karl; Rohde, Eva; Schallmoser, Katharina; Flicker, Karin; Lanzer, Gerhard; Linkesch, Werner; Speicher, Michael R; Strunk, Dirk.

Blood ; 113(26): 6716-25, 2009 Jun 25.

Article in English | MEDLINE | ID: mdl-19321860

17.

Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays.

Geigl, Jochen B; Obenauf, Anna C; Waldispuehl-Geigl, Julie; Hoffmann, Eva M; Auer, Martina; Hörmann, Martina; Fischer, Maria; Trajanoski, Zlatko; Schenk, Michael A; Baumbusch, Lars O; Speicher, Michael R.

Nucleic Acids Res ; 37(15): e105, 2009 Aug.

Article in English | MEDLINE | ID: mdl-19541849

18.

Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters.

Umkehrer, Christian; Holstein, Felix; Formenti, Laura; Jude, Julian; Froussios, Kimon; Neumann, Tobias; Cronin, Shona M; Haas, Lisa; Lipp, Jesse J; Burkard, Thomas R; Fellner, Michaela; Wiesner, Thomas; Zuber, Johannes; Obenauf, Anna C.

Nat Biotechnol ; 39(2): 174-178, 2021 02.

Article in English | MEDLINE | ID: mdl-32719478

19.

Down-regulation of A20 promotes immune escape of lung adenocarcinomas.

Breitenecker, Kristina; Homolya, Monika; Luca, Andreea C; Lang, Veronika; Trenk, Christoph; Petroczi, Georg; Mohrherr, Julian; Horvath, Jaqueline; Moritsch, Stefan; Haas, Lisa; Kurnaeva, Margarita; Eferl, Robert; Stoiber, Dagmar; Moriggl, Richard; Bilban, Martin; Obenauf, Anna C; Ferran, Christiane; Dome, Balazs; Laszlo, Viktoria; Gyorffy, Balázs; Dezso, Katalin; Moldvay, Judit; Casanova, Emilio; Moll, Herwig P.

Sci Transl Med ; 13(601)2021 07 07.

Article in English | MEDLINE | ID: mdl-34233950

20.

Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma.

Haas, Lisa; Elewaut, Anais; Gerard, Camille L; Umkehrer, Christian; Leiendecker, Lukas; Pedersen, Malin; Krecioch, Izabela; Hoffmann, David; Novatchkova, Maria; Kuttke, Mario; Neumann, Tobias; da Silva, Ines Pires; Witthock, Harriet; Cuendet, Michel A; Carotta, Sebastian; Harrington, Kevin J; Zuber, Johannes; Scolyer, Richard A; Long, Georgina V; Wilmott, James S; Michielin, Olivier; Vanharanta, Sakari; Wiesner, Thomas; Obenauf, Anna C.

Nat Cancer ; 2(7): 693-708, 2021 07.

Article in English | MEDLINE | ID: mdl-35121945

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