1.
Endocrinology
; 97(5): 1336-9, 1975 Nov.
Article
in English
| MEDLINE
| ID: mdl-1081049
ABSTRACT
Gel filtration of an extract of rat median eminence tissue in 0.1 N HCl on Sephadex G-25 separated two peaks, both with feeble ACTH-releasing activity. Full activity of the extract was regained when both peaks were recombined. This observation suggests that the ACTH-releasing hormone of the hypothalamus requires a co-factor for activity.
Subject(s)
Corticotropin-Releasing Hormone/isolation & purification , Hypothalamo-Hypophyseal System/analysis , Hypothalamus/analysis , Median Eminence/analysis , Animals , Biological Assay , Chromatography, Gel , Nerve Tissue Proteins/isolation & purification , Rats
2.
Endocrinology
; 89(4): 963-8, 1971 Oct.
Article
in English
| MEDLINE
| ID: mdl-4328500
Subject(s)
Adenine Nucleotides/pharmacology , Adrenal Glands/metabolism , Adrenocorticotropic Hormone/pharmacology , Corticosterone/biosynthesis , Adrenal Glands/drug effects , Animals , Corticosterone/analysis , Cyclic AMP/pharmacology , Fluorometry , In Vitro Techniques , Perfusion , Rats , Stimulation, Chemical
3.
Endocrinology
; 92(3): 679-86, 1973 Mar.
Article
in English
| MEDLINE
| ID: mdl-4349644
Subject(s)
Adrenal Glands/metabolism , Cyclic AMP/pharmacology , Steroids/biosynthesis , Adrenal Glands/drug effects , Adrenocorticotropic Hormone/administration & dosage , Adrenocorticotropic Hormone/pharmacology , Animals , Chromatography, Paper , Corticosterone , Cyclic AMP/administration & dosage , Female , Fluorescence , In Vitro Techniques , Rats , Time Factors , Tritium
4.
J Clin Endocrinol Metab
; 39(1): 150-3, 1974 Jul.
Article
in English
| MEDLINE
| ID: mdl-4365921
5.
A semi-automated in vitro assay for CRF: activities of peptides related to oxytocin and vasopressin.
Neuroendocrinology
; 15(2): 106-19, 1974.
Article
in English
| MEDLINE
| ID: mdl-4368352
6.
Biochem Biophys Res Commun
; 49(3): 748-51, 1972 Nov 01.
Article
in English
| MEDLINE
| ID: mdl-4344685