RELAY INTRASCLERAL 6-0 POLYPROPYLENE-ASSISTED INTRAOCULAR LENS FIXATION: A Retrospective Comparison With Modified Yamane Technique.

PURPOSE: To describe a new surgical technique that uses a relay suture to optimize sutureless scleral fixation of intraocular lens in eyes with capsular insufficiency and to evaluate the outcomes of this technique versus Flanged, double needle-guided, scleral fixation of intraocular lens with haptic trimming (modified Yamane approach). METHODS: Relay intrascleral 6-0 polypropylene sutures with flanges generated at the intraocular ends were used to fixate and securely hold a rigid intraocular lens with haptic eyelets against the inner scleral wall. The results were analyzed at 3-, 6-, and 12-month follow-up. RESULTS: This retrospective cohort study found that compared with the control group (n = 27), the relay-sutured group (n = 26) had greater mean changes in corneal astigmatism (0.44 vs. -0.52 diopters [D]) and fewer mean degrees of intraocular lens astigmatism (0.62 vs. 1.1 D). The mean intraocular lens decentration was comparable between both the groups; however, in the control group, there was a significant increase in intraocular lens tilt degrees from 3 to 12 months. Moreover, significantly higher proportions of patients with persistent macular edema and iris-optic capture were seen in the control group. CONCLUSION: The relay-sutured technique may be an alternative to flapless scleral fixation of intraocular lens and provides a stable intraocular lens position with acceptable complication rates.

Combine intravitreal bevacizumab injection with laser treatment for aggressive posterior retinopathy of prematurity (AP-ROP).

OBJECTIVE: To assess a new method the "Combine Treatment" consisted of diode laser photocoagulation and intravitreal bevacizumab for treatment of AP-ROP. MATERIAL AND METHOD: These retrospective and non-comparative case series study in twelve premature infants (7 Male, 5 Female) from ROP clinic with diagnosis of aggressive posterior retinopathy of prematurity (AP-ROP) based on indirect ophthalmoscopic examination were included in the present study. The "Combine Treatment" consisted of one treatment session in which diode laser photocoagulation was applied in the avascular zone (anterior and posterior to the presumed ridge include vascular nets up to the clear retina) followed by intravitreal injection of Bevacizumab (Avastin). Fundus photographs were obtained before and after the treatment using a wide-field digital pediatric imaging system (RetCam). RESULTS: Twenty-three eyes were treated with the "Combine Treatment". The rest were treated with only laser abrasion. All patients got favorable anatomical outcomes of all treated eyes. Proliferative tissue started regress 2 weeks after treatment and completed regress about 4.92 weeks (range; 3-7 weeks). There was neither progression of disease nor serious ocular or systemic complications. No further treatments were needed. CONCLUSION: In the present study, one session of the "Combine Treatment" leads to favorable anatomical outcomes for patients with AP-ROP. This new approach prevents aggressive progression and offers hope of good future vision to patients. The authors hope that this new approach will be another choice of treatment to prevent aggressive progression of the disease and gain good vision in the future.