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2.
Oftalmologia ; 53(2): 23-5, 2009.
Article in Ro | MEDLINE | ID: mdl-19697835

ABSTRACT

Ocular hypertension is an increase in the pressure in the eyes that is above the range considered normal with no detectable changes in vision or damage to the structure of your eyes. The term is used to distinguish people with elevated pressure from those with glaucoma, but not all people with ocular hypertension will develop this disease. However, there is an increased risk of glaucoma among those with ocular hypertension, so regular comprehensive eye examinations are essential to the overall eye health.


Subject(s)
Antihypertensive Agents/therapeutic use , Ocular Hypertension/drug therapy , Follow-Up Studies , Glaucoma/prevention & control , Global Health , Humans , Incidence , Intraocular Pressure/drug effects , Ocular Hypertension/epidemiology , Risk Factors , Romania/epidemiology , Tonometry, Ocular/methods , United States/epidemiology
3.
Oftalmologia ; 52(3): 73-6, 2008.
Article in Ro | MEDLINE | ID: mdl-19149122

ABSTRACT

C-reactive protein (CRP) is a systemic inflammatory marker associated with the cardiovascular risk profile. Some of the cardiovascular risk factors are linked with the development of age related macular degeneration (AMD), but the correlation between CRP and AMD is not yet well documented. Our current study is trying to emphasize the correlation between plasma CRP levels and the risk for AMD. In our study we used two groups of subjects homogenous by age and gender--group A formed of patients diagnosed with AMD and a group B with normal subjects to whom we measured the plasma levels of C-reactive protein using standard testing with high sensitivity. Our data suggests that there is a correlation between the elevated plasma levels of CPR and the stages of age related macular degeneration possibly implicating the inflammation in the etiopathogenic mechanism.


Subject(s)
C-Reactive Protein/metabolism , Macular Degeneration/blood , Aged , Biomarkers/blood , Case-Control Studies , Female , Humans , Inflammation/blood , Macular Degeneration/diagnosis , Male , Middle Aged , Risk Factors , Sensitivity and Specificity
4.
Oftalmologia ; 52(3): 87-90, 2008.
Article in Ro | MEDLINE | ID: mdl-19149125

ABSTRACT

UNLABELLED: The purpose of this paper is to evaluate the incidence of endophthalmitis after the phacoemulsification. MATERIAL AND METHODS: Retrospective clinical study that includes all the patients that have been operated and all cases of endophthalmitis survived after that in the period between 1.06.2007-31.05.2008 in the Central Military Hospital. RESULTS: There were 3 cases of exogenous endophthalmitis after the cataract surgery. In all of these cases: the inflammatory reaction was limited in the anterior chamber; phacoemulsification; there were no accidents in the cataract surgery; it was performed 2.75 mm clear corneal incision; it was no suture. CONCLUSION: There is a possibility of infections even after phacoemulsification without sutures.


Subject(s)
Cataract Extraction/adverse effects , Endophthalmitis/epidemiology , Endophthalmitis/etiology , Aged , Aged, 80 and over , Endophthalmitis/microbiology , Female , Humans , Incidence , Male , Phacoemulsification/adverse effects , Retrospective Studies , Romania/epidemiology
5.
Oftalmologia ; 52(3): 98-101, 2008.
Article in Ro | MEDLINE | ID: mdl-19149127

ABSTRACT

PURPOSE: To assess the macular structural changes in primary open angle glaucoma (POAG) patients. METHODS: A prospective clinical study, 6 months, two groups of patients--group A--case control--healthy subjects, and group B--POAG patients, divided in B1--early glaucoma and B2--advanced glaucoma. The groups were homogeneous about age and sex distribution. In all patients we have performed Humphrey Visual Field, 24-2 Sita Standard, and macular OCT. EXCLUSION CRITERIA: other ocular or systemic conditions. RESULTS AND CONCLUSIONS: In POAG group, we found macular changes comparing to the case-control group. Macular assessment in glaucoma is an important element to consider in the future.


Subject(s)
Glaucoma, Open-Angle/pathology , Macula Lutea/pathology , Algorithms , Case-Control Studies , Female , Glaucoma/pathology , Glaucoma, Open-Angle/diagnosis , Glaucoma, Open-Angle/physiopathology , Humans , Male , Optic Disk/pathology , Prospective Studies , Severity of Illness Index , Tomography, Optical Coherence , Visual Acuity , Visual Field Tests/methods
6.
Oftalmologia ; 51(4): 95-9, 2007.
Article in Ro | MEDLINE | ID: mdl-18543683

ABSTRACT

UNLABELLED: Prostaglandin analogs reduce intraocular pressure (IOP) by activation of matrixmetalloproteinase enzymes (MMP) and increasing uveoscleral outflow. MMP's were found in cornea and their activation could change the central corneal thickness (CCT). PURPOSE: To compare the effects of different prostaglandin analogues on central corneal thickness (CCT). METHODS: Clinical, observational, prospectively and randomised study during 3 month on 26 patients (52 eyes) newly diagnosed with primary open angle glaucoma or ocular hypertension. The patients were distributed in two groups concerning topical treatment: - group I: 15 patients treat with travoprost 0,004%; - group II: 11 patients treat with latanoprost 0,005%. The treatment was administrated daily at 9:00 pm, one drop. The CCT was measured for each patient for 3 times by ultrasound pachimetry: at the beginning of the study, at one month and three months. The groups were homogeneous concerning age and sex distribution. Exclusion criteria were: any topical eye drug usage, history of corneal disease or intraocular surgery. The statistic analyse was realised with Mann-Whitman test. RESULTS: The mean central corneal thickness for the two groups was similar: 521,27+/-28,54 microm for group I and 522,18+/-27,52 microm for group II. A statistically significant CCT reduction was observed in both groups: 516,88+/-28,61 microm at one month and 515,04+/-27,59 microm at three month for group I; respectively 518,41+/-27,36 microm at one month and 517,98+/-27,86 microm at three month for group II. CONCLUSIONS: The results of this study show that both classes of prostaglandin analogs reduce the mean CCT, the effect being equivalent for the both studied groups.


Subject(s)
Antihypertensive Agents/therapeutic use , Cloprostenol/analogs & derivatives , Cornea/drug effects , Intraocular Pressure/drug effects , Prostaglandins F, Synthetic/therapeutic use , Prostaglandins, Synthetic/therapeutic use , Aged , Cloprostenol/therapeutic use , Cornea/diagnostic imaging , Cornea/pathology , Female , Glaucoma, Open-Angle/drug therapy , Glaucoma, Open-Angle/pathology , Glaucoma, Open-Angle/physiopathology , Humans , Latanoprost , Male , Middle Aged , Ocular Hypertension/drug therapy , Ocular Hypertension/pathology , Ophthalmic Solutions/administration & dosage , Prospective Studies , Tonometry, Ocular , Travoprost , Treatment Outcome , Ultrasonography
7.
Oftalmologia ; 50(4): 86-9, 2006.
Article in Ro | MEDLINE | ID: mdl-17345811

ABSTRACT

PURPOSE: To compare the refractive stability of different kind of foldable intraocular lenses. METHOD: There was performed a two years (mean follow-up 7,4 +/- 1,2 months) prospective interventional case series study on 108 with senile cataract, without another ocular pathology which underwent cataract surgery by phacoemulsification and implantation of foldable intraocular lens (the same surgeon). Each patient had their refractive status measured at the 1-month postoperative visit, 3-months and at the 6-months follow-up visit. The results have been statistically analyzed using the Wilcoxon test. RESULTS: The postoperative refractive results were correlated with IOL design and material. The acrylic hydrophobic foldable intraocular lens with rigid haptics was more likely to move to hypermetropia and the acrylic hydrophobic foldable intraocular lens with pliable haptics showed minimal myopic movement. CONCLUSIONS: On long-term, the 1-piece acrylic hydrophobic IOL with soft acrylic loops had the most stable refractive results.


Subject(s)
Cataract Extraction/methods , Lens Implantation, Intraocular , Lenses, Intraocular , Refractive Errors/prevention & control , Acrylates , Aged , Aging , Humans , Phacoemulsification , Prospective Studies , Prosthesis Design , Statistics, Nonparametric , Visual Acuity
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