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1.

Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1.

Dauvilliers, Yves; Mignot, Emmanuel; Del Río Villegas, Rafael; Du, Yeting; Hanson, Elizabeth; Inoue, Yuichi; Kadali, Harisha; Koundourakis, Elena; Meyer, Seetha; Rogers, Raquel; Scammell, Thomas E; Sheikh, Sarah I; Swick, Todd; Szakács, Zoltan; von Rosenstiel, Philipp; Wu, Jingtao; Zeitz, Heidi; Murthy, N Venkatesha; Plazzi, Giuseppe; von Hehn, Christian.

N Engl J Med ; 389(4): 309-321, 2023 Jul 27.

Article in English | MEDLINE | ID: mdl-37494485

2.

Sleep modulates haematopoiesis and protects against atherosclerosis.

McAlpine, Cameron S; Kiss, Máté G; Rattik, Sara; He, Shun; Vassalli, Anne; Valet, Colin; Anzai, Atsushi; Chan, Christopher T; Mindur, John E; Kahles, Florian; Poller, Wolfram C; Frodermann, Vanessa; Fenn, Ashley M; Gregory, Annemijn F; Halle, Lennard; Iwamoto, Yoshiko; Hoyer, Friedrich F; Binder, Christoph J; Libby, Peter; Tafti, Mehdi; Scammell, Thomas E; Nahrendorf, Matthias; Swirski, Filip K.

Nature ; 566(7744): 383-387, 2019 02.

Article in English | MEDLINE | ID: mdl-30760925

3.

The neurobiological basis of narcolepsy.

Mahoney, Carrie E; Cogswell, Andrew; Koralnik, Igor J; Scammell, Thomas E.

Nat Rev Neurosci ; 20(2): 83-93, 2019 02.

Article in English | MEDLINE | ID: mdl-30546103

4.

Harriet Tubman's Hypersomnia: Insights from Historical and Medical Perspectives.

Balmuth, Evan A; Scammell, Thomas E.

J Gen Intern Med ; 38(16): 3621-3627, 2023 Dec.

Article in English | MEDLINE | ID: mdl-37740167

5.

Critical Dynamics and Coupling in Bursts of Cortical Rhythms Indicate Non-Homeostatic Mechanism for Sleep-Stage Transitions and Dual Role of VLPO Neurons in Both Sleep and Wake.

Lombardi, Fabrizio; Gómez-Extremera, Manuel; Bernaola-Galván, Pedro; Vetrivelan, Ramalingam; Saper, Clifford B; Scammell, Thomas E; Ivanov, Plamen Ch.

J Neurosci ; 40(1): 171-190, 2020 01 02.

Article in English | MEDLINE | ID: mdl-31694962

6.

Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control.

Venner, Anne; Mochizuki, Takatoshi; De Luca, Roberto; Anaclet, Christelle; Scammell, Thomas E; Saper, Clifford B; Arrigoni, Elda; Fuller, Patrick M.

J Neurosci ; 39(45): 8929-8939, 2019 11 06.

Article in English | MEDLINE | ID: mdl-31548232

7.

Catching Up on REMs.

Burgess, Christian R; Scammell, Thomas E.

N Engl J Med ; 386(20): 1950-1952, 2022 05 19.

Article in English | MEDLINE | ID: mdl-35584160

8.

Complementary roles of gasotransmitters CO and H2S in sleep apnea.

Peng, Ying-Jie; Zhang, Xiuli; Gridina, Anna; Chupikova, Irina; McCormick, David L; Thomas, Robert J; Scammell, Thomas E; Kim, Gene; Vasavda, Chirag; Nanduri, Jayasri; Kumar, Ganesh K; Semenza, Gregg L; Snyder, Solomon H; Prabhakar, Nanduri R.

Proc Natl Acad Sci U S A ; 114(6): 1413-1418, 2017 02 07.

Article in English | MEDLINE | ID: mdl-28115703

9.

GABAergic Neurons of the Central Amygdala Promote Cataplexy.

Mahoney, Carrie E; Agostinelli, Lindsay J; Brooks, Jessica N K; Lowell, Bradford B; Scammell, Thomas E.

J Neurosci ; 37(15): 3995-4006, 2017 04 12.

Article in English | MEDLINE | ID: mdl-28235898

10.

Cholinergic, Glutamatergic, and GABAergic Neurons of the Pedunculopontine Tegmental Nucleus Have Distinct Effects on Sleep/Wake Behavior in Mice.

Kroeger, Daniel; Ferrari, Loris L; Petit, Gaetan; Mahoney, Carrie E; Fuller, Patrick M; Arrigoni, Elda; Scammell, Thomas E.

J Neurosci ; 37(5): 1352-1366, 2017 02 01.

Article in English | MEDLINE | ID: mdl-28039375

11.

Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy.

Naganuma, Fumito; Bandaru, Sathyajit S; Absi, Gianna; Mahoney, Carrie E; Scammell, Thomas E; Vetrivelan, Ramalingam.

Neurobiol Dis ; 120: 12-20, 2018 12.

Article in English | MEDLINE | ID: mdl-30149182

12.

Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus.

Geerling, Joel C; Kim, Minjee; Mahoney, Carrie E; Abbott, Stephen B G; Agostinelli, Lindsay J; Garfield, Alastair S; Krashes, Michael J; Lowell, Bradford B; Scammell, Thomas E.

Am J Physiol Regul Integr Comp Physiol ; 310(1): R41-54, 2016 Jan 01.

Article in English | MEDLINE | ID: mdl-26491097

13.

Damage to histaminergic tuberomammillary neurons and other hypothalamic neurons with traumatic brain injury.

Valko, Philipp O; Gavrilov, Yury V; Yamamoto, Mihoko; Finn, Kristen; Reddy, Hasini; Haybaeck, Johannes; Weis, Serge; Scammell, Thomas E; Baumann, Christian R.

Ann Neurol ; 77(1): 177-82, 2015 Jan.

Article in English | MEDLINE | ID: mdl-25363332

14.

Optogenetic-mediated release of histamine reveals distal and autoregulatory mechanisms for controlling arousal.

Williams, Rhannan H; Chee, Melissa J S; Kroeger, Daniel; Ferrari, Loris L; Maratos-Flier, Eleftheria; Scammell, Thomas E; Arrigoni, Elda.

J Neurosci ; 34(17): 6023-9, 2014 Apr 23.

Article in English | MEDLINE | ID: mdl-24760861

15.

The roles of prostaglandin E2 and D2 in lipopolysaccharide-mediated changes in sleep.

Oishi, Yo; Yoshida, Kyoko; Scammell, Thomas E; Urade, Yoshihiro; Lazarus, Michael; Saper, Clifford B.

Brain Behav Immun ; 47: 172-7, 2015 Jul.

Article in English | MEDLINE | ID: mdl-25532785

16.

Amygdala lesions reduce cataplexy in orexin knock-out mice.

Burgess, Christian R; Oishi, Yo; Mochizuki, Takatoshi; Peever, John H; Scammell, Thomas E.

J Neurosci ; 33(23): 9734-42, 2013 Jun 05.

Article in English | MEDLINE | ID: mdl-23739970

17.

Role of the medial prefrontal cortex in cataplexy.

Oishi, Yo; Williams, Rhiannan H; Agostinelli, Lindsay; Arrigoni, Elda; Fuller, Patrick M; Mochizuki, Takatoshi; Saper, Clifford B; Scammell, Thomas E.

J Neurosci ; 33(23): 9743-51, 2013 Jun 05.

Article in English | MEDLINE | ID: mdl-23739971

18.

Orexin receptors: pharmacology and therapeutic opportunities.

Scammell, Thomas E; Winrow, Christopher J.

Annu Rev Pharmacol Toxicol ; 51: 243-66, 2011.

Article in English | MEDLINE | ID: mdl-21034217

19.

Emerging therapeutics in sleep.

Saper, Clifford B; Scammell, Thomas E.

Ann Neurol ; 74(3): 435-40, 2013 Sep.

Article in English | MEDLINE | ID: mdl-24038193

20.

Increase of histaminergic tuberomammillary neurons in narcolepsy.

Valko, Philipp O; Gavrilov, Yury V; Yamamoto, Mihoko; Reddy, Hasini; Haybaeck, Johannes; Mignot, Emmanuel; Baumann, Christian R; Scammell, Thomas E.

Ann Neurol ; 74(6): 794-804, 2013 Dec.

Article in English | MEDLINE | ID: mdl-24006291

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