Search details
1.
Intrinsic physicochemical profile of marketed antibody-based biotherapeutics.
Proc Natl Acad Sci U S A
; 118(37)2021 09 14.
Article
in English
| MEDLINE | ID: mdl-34504010
2.
Preclinical efficacy of humanized, non-FcγR-binding anti-CD3 antibodies in T-cell acute lymphoblastic leukemia.
Blood
; 136(11): 1298-1302, 2020 09 10.
Article
in English
| MEDLINE | ID: mdl-32483610
3.
Antibodies with Weakly Basic Isoelectric Points Minimize Trade-offs between Formulation and Physiological Colloidal Properties.
Mol Pharm
; 19(3): 775-787, 2022 03 07.
Article
in English
| MEDLINE | ID: mdl-35108018
4.
In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.
Mol Pharm
; 16(1): 86-95, 2019 01 07.
Article
in English
| MEDLINE | ID: mdl-30444371
5.
Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.
Mol Pharm
; 13(9): 2996-3003, 2016 09 06.
Article
in English
| MEDLINE | ID: mdl-27244474
6.
Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines.
J Biol Chem
; 288(37): 26583-93, 2013 Sep 13.
Article
in English
| MEDLINE | ID: mdl-23880771
7.
Geometric Antibody Engineering Reveals the Spatial Factor on the Efficacy of Bispecific T Cell Engagers.
ACS Chem Biol
; 19(4): 916-925, 2024 Apr 19.
Article
in English
| MEDLINE | ID: mdl-38491942
8.
Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
Med
; 3(12): 860-882.e15, 2022 Dec 09.
Article
in English
| MEDLINE | ID: mdl-36257298
9.
An adapted consensus protein design strategy for identifying globally optimal biotherapeutics.
MAbs
; 14(1): 2073632, 2022.
Article
in English
| MEDLINE | ID: mdl-35613320
10.
Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling.
J Biol Chem
; 285(27): 20850-9, 2010 Jul 02.
Article
in English
| MEDLINE | ID: mdl-20444694
11.
X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists.
J Biol Chem
; 284(50): 34553-60, 2009 Dec 11.
Article
in English
| MEDLINE | ID: mdl-19854829
12.
Discovery Strategies to Maximize the Clinical Potential of T-Cell Engaging Antibodies for the Treatment of Solid Tumors.
Antibodies (Basel)
; 9(4)2020 Nov 18.
Article
in English
| MEDLINE | ID: mdl-33217946
13.
A Bispecific DLL3/CD3 IgG-Like T-Cell Engaging Antibody Induces Antitumor Responses in Small Cell Lung Cancer.
Clin Cancer Res
; 26(19): 5258-5268, 2020 10 01.
Article
in English
| MEDLINE | ID: mdl-32554516
14.
Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.
PLoS One
; 14(6): e0218613, 2019.
Article
in English
| MEDLINE | ID: mdl-31251757
15.
bisFabs: Tools for rapidly screening hybridoma IgGs for their activities as bispecific antibodies.
MAbs
; 9(3): 430-437, 2017 04.
Article
in English
| MEDLINE | ID: mdl-28125314
16.
Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.
MAbs
; 9(8): 1297-1305, 2017.
Article
in English
| MEDLINE | ID: mdl-28854082
17.
Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding.
Structure
; 12(8): 1361-71, 2004 Aug.
Article
in English
| MEDLINE | ID: mdl-15296730
18.
An efficient route to bispecific antibody production using single-reactor mammalian co-culture.
MAbs
; 8(8): 1487-1497, 2016.
Article
in English
| MEDLINE | ID: mdl-27680183
19.
Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics.
Invest Ophthalmol Vis Sci
; 56(9): 5390-400, 2015 Aug.
Article
in English
| MEDLINE | ID: mdl-26275136
20.
Anti-CD20/CD3 T cell-dependent bispecific antibody for the treatment of B cell malignancies.
Sci Transl Med
; 7(287): 287ra70, 2015 May 13.
Article
in English
| MEDLINE | ID: mdl-25972002