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1.

Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.

Zhang, Jiasheng; Velmeshev, Dmitry; Hashimoto, Kei; Huang, Yu-Hsin; Hofmann, Jeffrey W; Shi, Xiaoyu; Chen, Jiapei; Leidal, Andrew M; Dishart, Julian G; Cahill, Michelle K; Kelley, Kevin W; Liddelow, Shane A; Seeley, William W; Miller, Bruce L; Walther, Tobias C; Farese, Robert V; Taylor, J Paul; Ullian, Erik M; Huang, Bo; Debnath, Jayanta; Wittmann, Torsten; Kriegstein, Arnold R; Huang, Eric J.

Nature ; 588(7838): 459-465, 2020 12.

Article in English | MEDLINE | ID: mdl-32866962

2.

Microtubule Plus End Dynamics - Do We Know How Microtubules Grow?: Cells boost microtubule growth by promoting distinct structural transitions at growing microtubule ends.

van Haren, Jeffrey; Wittmann, Torsten.

Bioessays ; 41(3): e1800194, 2019 03.

Article in English | MEDLINE | ID: mdl-30730055

3.

Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH.

Charafeddine, Rabab A; Cortopassi, Wilian A; Lak, Parnian; Tan, Ruensern; McKenney, Richard J; Jacobson, Matthew P; Barber, Diane L; Wittmann, Torsten.

J Biol Chem ; 294(22): 8779-8790, 2019 05 31.

Article in English | MEDLINE | ID: mdl-30992364

4.

GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics.

Pemble, Hayley; Kumar, Praveen; van Haren, Jeffrey; Wittmann, Torsten.

J Cell Sci ; 130(8): 1404-1412, 2017 04 15.

Article in English | MEDLINE | ID: mdl-28232523

5.

SnapShot: Microtubule regulators II.

Lyle, Karen; Kumar, Praveen; Wittmann, Torsten.

Cell ; 136(3): 566, 566.e1, 2009 Feb 06.

Article in English | MEDLINE | ID: mdl-19203588

6.

SnapShot: Microtubule Regulators I.

Lyle, Karen; Kumar, Praveen; Wittmann, Torsten.

Cell ; 136(2): 380, 380.e1, 2009 Jan 23.

Article in English | MEDLINE | ID: mdl-19167337

7.

Autophagy in adhesion and migration.

Kenific, Candia M; Wittmann, Torsten; Debnath, Jayanta.

J Cell Sci ; 129(20): 3685-3693, 2016 10 15.

Article in English | MEDLINE | ID: mdl-27672021

8.

LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.

Moon, Hyang Mi; Youn, Yong Ha; Pemble, Hayley; Yingling, Jessica; Wittmann, Torsten; Wynshaw-Boris, Anthony.

Hum Mol Genet ; 23(2): 449-66, 2014 Jan 15.

Article in English | MEDLINE | ID: mdl-24030547

9.

Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhabditis elegans.

Juang, Bi-Tzen; Ludwig, Anna L; Benedetti, Kelli L; Gu, Chen; Collins, Kimberly; Morales, Christopher; Asundi, Aarati; Wittmann, Torsten; L'Etoile, Noelle; Hagerman, Paul J.

Hum Mol Genet ; 23(18): 4945-59, 2014 Sep 15.

Article in English | MEDLINE | ID: mdl-24821701

10.

Acetylcholine receptor (AChR) clustering is regulated both by glycogen synthase kinase 3ß (GSK3ß)-dependent phosphorylation and the level of CLIP-associated protein 2 (CLASP2) mediating the capture of microtubule plus-ends.

Basu, Sreya; Sladecek, Stefan; Pemble, Hayley; Wittmann, Torsten; Slotman, Johan A; van Cappellen, Wiggert; Brenner, Hans-Rudolf; Galjart, Niels.

J Biol Chem ; 289(44): 30857-30867, 2014 Oct 31.

Article in English | MEDLINE | ID: mdl-25231989

11.

Neuronal deletion of GSK3ß increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.

Liz, Márcia A; Mar, Fernando M; Santos, Telma E; Pimentel, Helena I; Marques, Ana M; Morgado, Marlene M; Vieira, Sílvia; Sousa, Vera F; Pemble, Hayley; Wittmann, Torsten; Sutherland, Calum; Woodgett, James R; Sousa, Mónica M.

BMC Biol ; 12: 47, 2014 Jun 12.

Article in English | MEDLINE | ID: mdl-24923837

12.

Host microtubule plus-end binding protein CLASP1 influences sequential steps in the Trypanosoma cruzi infection process.

Zhao, Xiaoyan; Kumar, Praveen; Shah-Simpson, Sheena; Caradonna, Kacey L; Galjart, Niels; Teygong, Crystal; Blader, Ira; Wittmann, Torsten; Burleigh, Barbara A.

Cell Microbiol ; 15(4): 571-84, 2013 Apr.

Article in English | MEDLINE | ID: mdl-23107073

13.

Doublecortin reinforces microtubules to promote growth cone advance in soft environments.

Dema, Alessandro; Charafeddine, Rabab A; van Haren, Jeffrey; Rahgozar, Shima; Viola, Giulia; Jacobs, Kyle A; Kutys, Matthew L; Wittmann, Torsten.

bioRxiv ; 2024 Feb 29.

Article in English | MEDLINE | ID: mdl-38464100

14.

Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress.

Liboy-Lugo, José M; Espinoza, Carla A; Sheu-Gruttadauria, Jessica; Park, Jesslyn E; Xu, Albert; Jowhar, Ziad; Gao, Angela L; Carmona-Negrón, José A; Wittmann, Torsten; Jura, Natalia; Floor, Stephen N.

bioRxiv ; 2024 Feb 07.

Article in English | MEDLINE | ID: mdl-38370785

15.

Multisite phosphorylation disrupts arginine-glutamate salt bridge networks required for binding of cytoplasmic linker-associated protein 2 (CLASP2) to end-binding protein 1 (EB1).

Kumar, Praveen; Chimenti, Michael S; Pemble, Hayley; Schönichen, André; Thompson, Oliver; Jacobson, Matthew P; Wittmann, Torsten.

J Biol Chem ; 287(21): 17050-17064, 2012 May 18.

Article in English | MEDLINE | ID: mdl-22467876

16.

Analysis of microtubule dynamic instability using a plus-end growth marker.

Matov, Alexandre; Applegate, Kathryn; Kumar, Praveen; Thoma, Claudio; Krek, Wilhelm; Danuser, Gaudenz; Wittmann, Torsten.

Nat Methods ; 7(9): 761-8, 2010 Sep.

Article in English | MEDLINE | ID: mdl-20729842

17.

Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.

Elwell, Cherilyn A; Jiang, Shaobo; Kim, Jung Hwa; Lee, Albert; Wittmann, Torsten; Hanada, Kentaro; Melancon, Paul; Engel, Joanne N.

PLoS Pathog ; 7(9): e1002198, 2011 Sep.

Article in English | MEDLINE | ID: mdl-21909260

18.

Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant.

Dema, Alessandro; Charafeddine, Rabab; Rahgozar, Shima; van Haren, Jeffrey; Wittmann, Torsten.

Elife ; 122023 01 30.

Article in English | MEDLINE | ID: mdl-36715499

19.

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.

Delorme, Violaine; Machacek, Matthias; DerMardirossian, Céline; Anderson, Karen L; Wittmann, Torsten; Hanein, Dorit; Waterman-Storer, Clare; Danuser, Gaudenz; Bokoch, Gary M.

Dev Cell ; 13(5): 646-662, 2007 Nov.

Article in English | MEDLINE | ID: mdl-17981134

20.

Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules.

Dema, Alessandro; van Haren, Jeffrey; Wittmann, Torsten.

Curr Biol ; 32(5): 1197-1205.e4, 2022 03 14.

Article in English | MEDLINE | ID: mdl-35090591

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