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1.
High-Throughput Analyses of Therapeutic Antibodies Using High-Field Asymmetric Waveform Ion Mobility Spectrometry Combined with SampleStream and Intact Protein Mass Spectrometry.
Anal Chem
; 95(47): 17263-17272, 2023 11 28.
Article
in English
| MEDLINE | ID: mdl-37956201
2.
Meropenem-Tobramycin Combination Regimens Combat Carbapenem-Resistant Pseudomonas aeruginosa in the Hollow-Fiber Infection Model Simulating Augmented Renal Clearance in Critically Ill Patients.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Article
in English
| MEDLINE | ID: mdl-31636062
3.
Meropenem Combined with Ciprofloxacin Combats Hypermutable Pseudomonas aeruginosa from Respiratory Infections of Cystic Fibrosis Patients.
Antimicrob Agents Chemother
; 62(11)2018 11.
Article
in English
| MEDLINE | ID: mdl-30104278
4.
Combating Carbapenem-Resistant Acinetobacter baumannii by an Optimized Imipenem-plus-Tobramycin Dosage Regimen: Prospective Validation via Hollow-Fiber Infection and Mathematical Modeling.
Antimicrob Agents Chemother
; 62(4)2018 04.
Article
in English
| MEDLINE | ID: mdl-29339388
5.
Optimization and Evaluation of Piperacillin-Tobramycin Combination Dosage Regimens against Pseudomonas aeruginosa for Patients with Altered Pharmacokinetics via the Hollow-Fiber Infection Model and Mechanism-Based Modeling.
Antimicrob Agents Chemother
; 62(5)2018 05.
Article
in English
| MEDLINE | ID: mdl-29463528
6.
Optimization of a Meropenem-Tobramycin Combination Dosage Regimen against Hypermutable and Nonhypermutable Pseudomonas aeruginosa via Mechanism-Based Modeling and the Hollow-Fiber Infection Model.
Antimicrob Agents Chemother
; 62(4)2018 04.
Article
in English
| MEDLINE | ID: mdl-29437610
7.
Optimization of Synergistic Combination Regimens against Carbapenem- and Aminoglycoside-Resistant Clinical Pseudomonas aeruginosa Isolates via Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling.
Antimicrob Agents Chemother
; 61(1)2017 01.
Article
in English
| MEDLINE | ID: mdl-27821448
8.
Evaluation of Pharmacokinetic/Pharmacodynamic Model-Based Optimized Combination Regimens against Multidrug-Resistant Pseudomonas aeruginosa in a Murine Thigh Infection Model by Using Humanized Dosing Schemes.
Antimicrob Agents Chemother
; 61(12)2017 12.
Article
in English
| MEDLINE | ID: mdl-28993331
9.
Aminoglycoside Concentrations Required for Synergy with Carbapenems against Pseudomonas aeruginosa Determined via Mechanistic Studies and Modeling.
Antimicrob Agents Chemother
; 61(12)2017 12.
Article
in English
| MEDLINE | ID: mdl-28893782
10.
Single Intravenous Dose of Novel Flurbiprofen-Loaded Proniosome Formulations Provides Prolonged Systemic Exposure and Anti-inflammatory Effect.
Mol Pharm
; 13(11): 3688-3699, 2016 11 07.
Article
in English
| MEDLINE | ID: mdl-27632682
11.
Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity.
Mol Pharm
; 13(4): 1229-41, 2016 Apr 04.
Article
in English
| MEDLINE | ID: mdl-26871003
12.
Novel approach to optimize synergistic carbapenem-aminoglycoside combinations against carbapenem-resistant Acinetobacter baumannii.
Antimicrob Agents Chemother
; 59(4): 2286-98, 2015 Apr.
Article
in English
| MEDLINE | ID: mdl-25645842
13.
Two mechanisms of killing of Pseudomonas aeruginosa by tobramycin assessed at multiple inocula via mechanism-based modeling.
Antimicrob Agents Chemother
; 59(4): 2315-27, 2015 Apr.
Article
in English
| MEDLINE | ID: mdl-25645838
14.
Bacillus Calmette-Guérin vaccine induces a selective serotonin reuptake inhibitor (SSRI)-resistant depression like phenotype in mice.
Brain Behav Immun
; 42: 204-11, 2014 Nov.
Article
in English
| MEDLINE | ID: mdl-25016199
15.
Repeat-dose and embryo-fetal developmental toxicity of zinpentraxin alfa.
Reprod Toxicol
; 123: 108526, 2024 Jan.
Article
in English
| MEDLINE | ID: mdl-38141866
16.
Successful Development of Nonclinical Anti-Drug Antibody Assays to Support Zinpentraxin Alfa Reproductive Toxicology Studies.
AAPS J
; 26(1): 16, 2024 01 24.
Article
in English
| MEDLINE | ID: mdl-38267613
17.
Comparative Pharmacokinetics and Safety Assessment of 1st- and 2nd-Generation Zinpentraxin Alfa Drug Products in Healthy Volunteers: A Randomized Crossover Study.
Clin Pharmacol Drug Dev
; 13(6): 655-664, 2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38651245
18.
A Phase 1a Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7303509, an Anti-TGFß3 Antibody, in Healthy Volunteers.
Rheumatol Ther
; 11(3): 755-771, 2024 Jun.
Article
in English
| MEDLINE | ID: mdl-38662148
19.
Isoform-selective TGF-ß3 inhibition for systemic sclerosis.
Med
; 5(2): 132-147.e7, 2024 Feb 09.
Article
in English
| MEDLINE | ID: mdl-38272035
20.
Complex PK-PD of an engineered IL-15/IL-15Rα-Fc fusion protein in cynomolgus monkeys: QSP modeling of lymphocyte dynamics.
Eur J Pharm Sci
; 186: 106450, 2023 Jul 01.
Article
in English
| MEDLINE | ID: mdl-37084985