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1.
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.
Proc Natl Acad Sci U S A
; 118(6)2021 02 09.
Article
in English
| MEDLINE | ID: mdl-33526699
2.
Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice.
Proc Natl Acad Sci U S A
; 117(5): 2579-2587, 2020 02 04.
Article
in English
| MEDLINE | ID: mdl-31964819
3.
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
Proc Natl Acad Sci U S A
; 111(45): 16082-7, 2014 Nov 11.
Article
in English
| MEDLINE | ID: mdl-25349431
4.
Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity.
Sci Adv
; 7(40): eabj3658, 2021 Oct.
Article
in English
| MEDLINE | ID: mdl-34586848
5.
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.
Nat Med
; 24(1): 50-61, 2018 01.
Article
in English
| MEDLINE | ID: mdl-29176737
6.
Intravenous immune globulin suppresses angiogenesis in mice and humans.
Signal Transduct Target Ther
; 12016.
Article
in English
| MEDLINE | ID: mdl-26925256
7.
Human IgG1 antibodies suppress angiogenesis in a target-independent manner.
Signal Transduct Target Ther
; 12016.
Article
in English
| MEDLINE | ID: mdl-26918197
8.
Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice.
Invest Ophthalmol Vis Sci
; 56(12): 7122-9, 2015 Nov.
Article
in English
| MEDLINE | ID: mdl-26529046
9.
Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome.
Cell Rep
; 11(11): 1686-93, 2015 Jun 23.
Article
in English
| MEDLINE | ID: mdl-26074074
10.
Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity.
Science
; 346(6212): 1000-3, 2014 Nov 21.
Article
in English
| MEDLINE | ID: mdl-25414314
11.
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy.
Invest Ophthalmol Vis Sci
; 54(12): 7395-401, 2013 Nov 11.
Article
in English
| MEDLINE | ID: mdl-24114535
12.
IL-18 is not therapeutic for neovascular age-related macular degeneration.
Nat Med
; 20(12): 1372-5, 2014 Dec.
Article
in English
| MEDLINE | ID: mdl-25473914
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