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1.

POT1 recruits and regulates CST-Polα/primase at human telomeres.

Cai, Sarah W; Takai, Hiroyuki; Zaug, Arthur J; Dilgen, Teague C; Cech, Thomas R; Walz, Thomas; de Lange, Titia.

Cell ; 2024 May 29.

Article in English | MEDLINE | ID: mdl-38838667

2.

Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.

Hadi, Kevin; Yao, Xiaotong; Behr, Julie M; Deshpande, Aditya; Xanthopoulakis, Charalampos; Tian, Huasong; Kudman, Sarah; Rosiene, Joel; Darmofal, Madison; DeRose, Joseph; Mortensen, Rick; Adney, Emily M; Shaiber, Alon; Gajic, Zoran; Sigouros, Michael; Eng, Kenneth; Wala, Jeremiah A; Wrzeszczynski, Kazimierz O; Arora, Kanika; Shah, Minita; Emde, Anne-Katrin; Felice, Vanessa; Frank, Mayu O; Darnell, Robert B; Ghandi, Mahmoud; Huang, Franklin; Dewhurst, Sally; Maciejowski, John; de Lange, Titia; Setton, Jeremy; Riaz, Nadeem; Reis-Filho, Jorge S; Powell, Simon; Knowles, David A; Reznik, Ed; Mishra, Bud; Beroukhim, Rameen; Zody, Michael C; Robine, Nicolas; Oman, Kenji M; Sanchez, Carissa A; Kuhner, Mary K; Smith, Lucian P; Galipeau, Patricia C; Paulson, Thomas G; Reid, Brian J; Li, Xiaohong; Wilkes, David; Sboner, Andrea; Mosquera, Juan Miguel.

Cell ; 183(1): 197-210.e32, 2020 10 01.

Article in English | MEDLINE | ID: mdl-33007263

3.

Author Correction: Telomeres in cancer: tumour suppression and genome instability.

Maciejowski, John; de Lange, Titia.

Nat Rev Mol Cell Biol ; 20(4): 259, 2019 Apr.

Article in English | MEDLINE | ID: mdl-30816301

4.

CST-Polα/Primase: the second telomere maintenance machine.

Cai, Sarah W; de Lange, Titia.

Genes Dev ; 37(13-14): 555-569, 2023 07 01.

Article in English | MEDLINE | ID: mdl-37495394

5.

53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair.

Lottersberger, Francisca; Karssemeijer, Roos Anna; Dimitrova, Nadya; de Lange, Titia.

Cell ; 163(4): 880-93, 2015 Nov 05.

Article in English | MEDLINE | ID: mdl-26544937

6.

Chromothripsis and Kataegis Induced by Telomere Crisis.

Maciejowski, John; Li, Yilong; Bosco, Nazario; Campbell, Peter J; de Lange, Titia.

Cell ; 163(7): 1641-54, 2015 Dec 17.

Article in English | MEDLINE | ID: mdl-26687355

7.

CST-polymerase α-primase solves a second telomere end-replication problem.

Takai, Hiroyuki; Aria, Valentina; Borges, Pamela; Yeeles, Joseph T P; de Lange, Titia.

Nature ; 627(8004): 664-670, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38418884

8.

TRF1 uses a noncanonical function of TFIIH to promote telomere replication.

Yang, Zhe; Sharma, Keshav; de Lange, Titia.

Genes Dev ; 36(17-18): 956-969, 2022 09 01.

Article in English | MEDLINE | ID: mdl-36229075

9.

Telomeres in cancer: tumour suppression and genome instability.

Maciejowski, John; de Lange, Titia.

Nat Rev Mol Cell Biol ; 18(3): 175-186, 2017 03.

Article in English | MEDLINE | ID: mdl-28096526

10.

The evolution of metazoan shelterin.

Myler, Logan R; Kinzig, Charles G; Sasi, Nanda K; Zakusilo, George; Cai, Sarah W; de Lange, Titia.

Genes Dev ; 35(23-24): 1625-1641, 2021 12 01.

Article in English | MEDLINE | ID: mdl-34764137

11.

Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.

Doksani, Ylli; Wu, John Y; de Lange, Titia; Zhuang, Xiaowei.

Cell ; 155(2): 345-356, 2013 Oct 10.

Article in English | MEDLINE | ID: mdl-24120135

12.

53BP1: a DSB escort.

Mirman, Zachary; de Lange, Titia.

Genes Dev ; 34(1-2): 7-23, 2020 01 01.

Article in English | MEDLINE | ID: mdl-31896689

13.

Break-induced replication promotes fragile telomere formation.

Yang, Zhe; Takai, Kaori K; Lovejoy, Courtney A; de Lange, Titia.

Genes Dev ; 34(19-20): 1392-1405, 2020 10 01.

Article in English | MEDLINE | ID: mdl-32883681

14.

Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.

Wu, Peng; Takai, Hiroyuki; de Lange, Titia.

Cell ; 150(1): 39-52, 2012 Jul 06.

Article in English | MEDLINE | ID: mdl-22748632

15.

Shelterin-Mediated Telomere Protection.

de Lange, Titia.

Annu Rev Genet ; 52: 223-247, 2018 11 23.

Article in English | MEDLINE | ID: mdl-30208292

16.

DNA-PK controls Apollo's access to leading-end telomeres.

Sonmez, Ceylan; Toia, Beatrice; Eickhoff, Patrik; Matei, Andreea Medeea; El Beyrouthy, Michael; Wallner, Björn; Douglas, Max E; de Lange, Titia; Lottersberger, Francisca.

Nucleic Acids Res ; 52(8): 4313-4327, 2024 May 08.

Article in English | MEDLINE | ID: mdl-38407308

17.

Rate my Editor.

de Lange, Titia.

Genes Dev ; 37(1-2): 14-15, 2023 Jan 01.

Article in English | MEDLINE | ID: mdl-37061981

18.

Persistent telomere damage induces bypass of mitosis and tetraploidy.

Davoli, Teresa; Denchi, Eros Lazzerini; de Lange, Titia.

Cell ; 141(1): 81-93, 2010 Apr 02.

Article in English | MEDLINE | ID: mdl-20371347

19.

The causes and consequences of polyploidy in normal development and cancer.

Davoli, Teresa; de Lange, Titia.

Annu Rev Cell Dev Biol ; 27: 585-610, 2011.

Article in English | MEDLINE | ID: mdl-21801013

20.

Shelterin is a dimeric complex with extensive structural heterogeneity.

Zinder, John C; Olinares, Paul Dominic B; Svetlov, Vladimir; Bush, Martin W; Nudler, Evgeny; Chait, Brian T; Walz, Thomas; de Lange, Titia.

Proc Natl Acad Sci U S A ; 119(31): e2201662119, 2022 08 02.

Article in English | MEDLINE | ID: mdl-35881804

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