ChatGPT and dentistry: a step toward the future.

This article aims to explore the integration of ChatGPT, an advanced conversational artificial intelligence model, in the field of dentistry. The review primarily consists of information related to the capabilities and functionalities of ChatGPT and how these abilities can aid dental professionals. This study includes data from research papers, case studies, and relevant literature on language models, as well as papers on dentistry, patient communication, dental education, and clinical decision-making. A systematic approach was used to select relevant studies and literature. The selection criteria focused on papers that specifically discussed the integration of language models, ChatGPT in particular, in dentistry and their applications. The study findings revealed that ChatGPT has significant potential to revolutionize dentistry by offering various applications and benefits. It can enhance patient engagement and understanding through personalized oral health information and guidance. In dental education, ChatGPT can provide interactive learning, case studies, and virtual patient simulations. ChatGPT can also assist researchers in analyzing dental literature, identifying patterns, and generating insights. Moreover, it supports dentists with evidence-based recommendations, treatment options, and diagnostic support. Integrating ChatGPT in dentistry can be highly beneficial, but it is crucial to address ethical considerations, accuracy, and privacy concerns. Responsible implementation and continuous improvement of its functionalities are necessary to ensure that patient care and outcomes are improved.

New biomaterials for modern dentistry.

Whilst the appropriate assessment criteria for dental biomaterials is debated, there has been an increasing interest in the use of dental biomaterials for oral rehabilitation. Consequently, a variety of new biomaterials have been introduced in dentistry. To address this issue, BMC Oral Health has launched a Collection on "New biomaterials for modern dentistry".

Angiogenesis in Regenerative Dentistry: Are We Far Enough for Therapy?

Angiogenesis is a broad spread term of high interest in regenerative medicine and tissue engineering including the dental field. In the last two decades, researchers worldwide struggled to find the best ways to accelerate healing, stimulate soft, and hard tissue remodeling. Stem cells, growth factors, pathways, signals, receptors, genetics are just a few words that describe this area in medicine. Dental implants, bone and soft tissue regeneration using autologous grafts, or xenografts, allografts, their integration and acceptance rely on their material properties. However, the host response, through its vascularization, plays a significant role. The present paper aims to analyze and organize the latest information about the available dental stem cells, the types of growth factors with pro-angiogenic effect and the possible therapeutic effect of enhanced angiogenesis in regenerative dentistry.

Redesigning Dentistry-A Perspective Based in History.

Why is dentistry set up separately from mainstream medicine? It seems unnatural. The reason is embedded in historical shadows, as for centuries, dental disease and its treatments were accompanied by excruciating pain and human misery. Early itinerant dentists were in demand because the need for relief was so urgent and great, resulting in dentistry became an independent profession. However, toothache may no longer be a significant public health problem. Despite some pressures from present-day interlopers such as osteopathy schools, dental and oral medicine can and should fold back into mainstream medicine as one of the natural units of medical care. While undoing the existing educational and organizational infrastructure may be a nearly impossible task, there may be a way these perceived obstacles can be circumvented. Those responsible for the administration of medical education should be encouraged to create pathways for their Doctor of Medicine (Medicinae Doctor ­ M.D.) -seeking students to pursue dental/oral medicine as a bona fide specialty of medicine. The time appears right for this redirection in dental education.

Scientific Publications in Dentistry in Lithuania, Latvia, and Estonia Between 1996 and 2018: A Bibliometric Analysis.

This study aimed to determine the number and quality of scientific publications in dentistry from the Baltic countries of Lithuania, Latvia, and Estonia between 1996 and 2018 using bibliometric analysis. Web of Science and Scopus were searched to identify scientific publications in dentistry between 1996 and 2018 by authors from centers in Lithuania, Latvia, and Estonia. The annual number of scientific publications, citation rate, and h-index for each publication, and trends in international co-authorship were investigated by country and institution. There were 651 scientific publications in dentistry between 1996 and 2018, by authors from Lithuania (280 publications), Latvia (210 publications), and Estonia (161 publications). Publications from Estonia were ranked highest in qualitative terms (citation rate and h-index), followed by Lithuania, and Latvia. Of 28 authors with at least ten publications, 54% were Lithuanian (15 authors), 25% were Estonian (7 authors), and 21% were Latvian (6 authors). Estonian authors collaborated mainly with Finland (27 publications), Latvian authors with the USA (16 publications), and Lithuanian authors with Canada (26 publications). Most publications came from the academic institutions of the Lithuanian University of Health Sciences (136 publications), the University of Tartu (109 publications), Vilnius University (101 publications), and Riga Stradins University (28 publications). During the past 22 years, authors from Lithuania had the most publications in the field of dentistry, and authors from Estonia had the most cited publications. Authors mainly published in native journals and collaborated with authors in Scandinavia and North America.

Stem Cells for the Oromaxillofacial Area: Could they be a promising source for regeneration in dentistry?

Oromaxillofacial tissues (OMT) are composed of tooth and bone, together with nerves and blood vessels. Such a composite material is a huge source for mesenchymal stem cells (MSCs) that can be obtained with ease from extracted teeth, teeth structures and socket blood, flapped gingiva tissue, and mandibular/maxillar bone marrow. They offer a biological answer for restoring damaged dental tissues such as the regeneration of alveolar bone, prevention of pulp tissue defects, and dental structures. Dental tissue-derived mesenchymal stem cells share properties with bone marrow-derived mesenchymal stem cells and there is a considerable potential for these cells to be used in different stem cell-based therapies, such as bone and nerve regeneration. Dental pulp tissue might be a very good source for neurological disorders whereas gingiva-derived mesenchymal stem cells could be a good immune modulatory/suppressive mediators. OMT-MSCs is also promising candidates for regeneration of orofacial tissues from the perspective of developmental fate. Here, we review the fundamental biology and potential for future regeneration strategies of MSCs in oromaxillofacial research.

Matrix metalloproteinases and inhibitors in dentistry.

OBJECTIVES: Matrix metalloproteinase (MMP) expression has been associated with tissue development, invasive cancer cell behavior, and inflammation. The associations of increased expression of MMPs with diseases have led to intensive research activities to develop MMP inhibitors. Here, the questions are addressed which associations between increased levels of any MMP with dental diseases may be cause or consequence, whether MMP levels may be of diagnostic value and whether and which MMP inhibitors need further investigations for use in dental diseases. METHODS: To study the role of MMPs and to discriminate between cause or consequence, the literature about measurements of MMPs and about the use of inhibitory drugs and genetic knockout animal models in dentistry was compared. RESULTS: The only FDA-approved treatment with MMP inhibitors is tetracyclines for periodontitis, whereas a diagnostic test for activated MMP-8 in oral fluids is valued in practical periodontology. The MMP literature in dentistry is artificially skewed to the gelatinases MMP-2 and MMP-9 and to enamelysin, alias MMP-20. The basis for this observation is, respectively, the widely used and sensitive technique of gelatin zymography and enamel proteins as substrates of MMP-20. Studies on additional MMPs are gaining interest in dentistry and MMP inhibitors may provide new applications. In addition, drugs with proven effects for the treatment of dental diseases may be found to act through MMP inhibition. CONCLUSION AND RELEVANCE: In conclusion, research on MMPs and inhibitors may provide practical applications beyond diagnosis and treatment of periodontitis and will be, directly or indirectly, beneficial for patients with dental or periodontal diseases.

Gender Inequalities in the Dental Workforce: Global Perspectives.

The aim of this review is to investigate the growth of diversity and inclusion in global academic dental research with a focus on gender equality. A diverse range of research methodologies were used to conduct this review, including an extensive review of the literature, engagement of key informants in dental academic leadership positions around the world, and review of current data from a variety of national and international organizations. Results provide evidence of gender inequalities that currently persist in dental academics and research. Although the gender gap among graduating dental students in North America and the two most populous countries in Europe (the United Kingdom and France) has been narrowed, women make up 30% to 40% of registered dentists in countries throughout Europe, Oceania, Asia, and Africa. In academic dentistry around the globe, greater gender inequality was found to correlate with higher ranking academic and leadership positions in the United States, United Kingdom, several countries in European Union, Japan, and Saudi Arabia. Further disparities are noted in the dental research sector, where women make up 33% of dental researchers in the European Union, 35% in North America, 55% in Brazil, and 25% in Japan. Family and societal pressures, limited access to research funding, and lack of mentoring and leadership training opportunities are reported as also contributing to gender inequalities. To continue advancing gender equality in dental academia and research, efforts should be geared toward the collection and public dissemination of data on gender-specific distributions. Such evidence-driven information will guide the selection of future strategies and best practices for promoting gender equity in the dental workforce, which provides a major pipeline of researchers and scholars for the dental profession.

[Health economics and oral care: an introductory anthology]. / Gezondheidseconomie en mondzorg: een inleidende bloemlezing.

Healthcare expenditures will continue to increase in the coming years, raising questions regarding the sustainability of the Dutch healthcare system and solidarity, but also about the optimal use of available resources. Given the issues in the oral care sector, attention for economic insights is appropriate there as well. Relevant issues in this regard are the design of the basic and supplementary health insurance schemes for oral care, the market structure and financing of oral care, questions regarding task shifting in oral care, as well as socio-economic inequalities in oral health. A closer cooperative relationship between oral care and the health economy can help in achieving an optimal and sustainable organisation of the Dutch oral care sector. In other words, an organisation contributing in an efficient and fair way to good oral care for all Dutch citizens.

Digital flow in medicine and dentistry: what’s new?

The increasing requirements of standardization in medical applications have led physicians towards a deep revision of their protocols. The phenomenon of ‘digital health’ has revolutionized the way a patient accesses medical information, but it has also improved the way the doctor handles the surgical and clinical phases. In digital dentistry, the working steps are mainly reported as digital image acquisition, preparation and/or processing of data, device production and clinical application on patients; the new technologies have brought significant benefits to both the dentist and the patient. Digital processing of anatomical data uses virtual models, which represent a precise representation of the patient’s anatomy. Recent advances in digital image acquisition technologies and the enormous complexity of modern software have made intraoral scans possible to realize digital dental arch models, however, the digital model is able to report substantial information to the clinician. Therefore, both complex surgeries and less invasive local therapies can be easily planned, with an accurate analysis of biological regulators improving the regenerative procedures, to achieve the best results in a shorter treatment.

About stem cell research in dentistry: many doubts and too many pitfalls still affect the regenerative dentistry.

Stem cells (SCs) research is one of the most promising approaches to regenerative medicine. Our understanding of SCs biology and their potential role in tissue repairing has notably increased during the last few years. Mesenchymal stem cells (MSCs) are present in almost all human tissues, including oral and dental tissues (dental-derived stem cells or DDSCs). Despite many doubts and too many pitfalls still affect regenerative dentistry; however, it represents an exciting challenge for the next generations of young dentists. Educating and training in regenerative medicine the new generation of researchers is of utmost importance, albeit often underestimated: regenerative dentistry represents a big opportunity for the next generations of researchers and clinicians, and this review report underlines that dental schools should pay more attention to teachings of strategic subjects, such as cell biology, molecular biology and tissue engineering.

Bioceramics for Clinical Application in Regenerative Dentistry.

Bioceramics represent functional ceramics with significant interest in regenerative medicine area. In orthopedics as well as in oral and maxillofacial surgery, bioceramics have been widely used as bone reconstructive materials. The most common one is hydroxyapatite which have been in the market and clinical applications since the mid of 1970s. Nowadays, a lot of works have been being in the pipeline to develop bioceramics for various clinical applications in regenerative medicine area, including dentistry. Bioceramics have been used and considered promising candidate for periodontal treatment, prevention of relapse, nerve regeneration, vaccine adjuvant, drug delivery technology, even for esthetic medicine and cosmetics. In this chapter, the advantages of bioceramics for regenerative therapy especially in dentistry is discussed. The overview of bioceramics classification is also explained. The future perspective and challenges on the use of bioceramics for next generation regenerative therapy is also discussed.

Reach of Messages in a Dental Twitter Network: Cohort Study Examining User Popularity, Communication Pattern, and Network Structure.

BACKGROUND: Increasing the reach of messages disseminated through Twitter promotes the success of Twitter-based health education campaigns. OBJECTIVE: This study aimed to identify factors associated with reach in a dental Twitter network (1) initially and (2) sustainably at individual and network levels. METHODS: We used instructors' and students' Twitter usernames from a Saudi dental school in 2016-2017 and applied Gephi (a social network analysis tool) and social media analytics to calculate user and network metrics. Content analysis was performed to identify users disseminating oral health information. The study outcomes were reach at baseline and sustainably over 1.5 years. The explanatory variables were indicators of popularity (number of followers, likes, tweets retweeted by others), communication pattern (number of tweets, retweets, replies, tweeting/ retweeting oral health information or not). Multiple logistic regression models were used to investigate associations. RESULTS: Among dental users, 31.8% had reach at baseline and 62.9% at the end of the study, reaching a total of 749,923 and dropping to 37,169 users at the end. At an individual level, reach was associated with the number of followers (baseline: odds ratio, OR=1.003, 95% CI=1.001-1.005 and sustainability: OR=1.002, 95% CI=1.0001-1.003), likes (baseline: OR=1.001, 95% CI=1.0001-1.002 and sustainability: OR=1.0031, 95% CI=1.0003-1.002), and replies (baseline: OR=1.02, 95% CI=1.005-1.04 and sustainability: OR=1.02, 95% CI=1.004-1.03). At the network level, users with the least followers, tweets, retweets, and replies had the greatest reach. CONCLUSIONS: Reach was reduced by time. Factors increasing reach at the user level had different impact at the network level. More than one strategy is needed to maximize reach.

Fifteen Years of Platelet Rich Fibrin in Dentistry and Oromaxillofacial Surgery: How High is the Level of Scientific Evidence?

Platelet-rich fibrin is a blood concentrate system used for soft tissue and bone tissue regeneration. In the last decade, platelet rich fibrin (PRF) has been widely used in different indication fields, particularly in oral and maxillofacial surgery. This review investigates the level of scientific evidence of published articles related to the use of PRF for bone and soft tissue regeneration in dentistry and maxillofacial surgery. An electronic literature research using the biomedical search engine "National Library of Medicine" (PubMed-MEDLINE) was performed in May 2017. A total of 392 articles were found, 72 of which were classified for each indication field. When comparing PRF with biomaterials vs biomaterial alone in sinus lift (5 studies; IIa), no statistically significant differences were detected. Socket preservation and ridge augmentation using PRF significantly enhanced new bone formation compared to healing without PRF (7 studies Ib, IIa, IIb). Reepithelialization and bone regeneration was achieved in 96 of 101 patients diagnosed with medication-related osteonecrosis of the jaw (5 studies, III). In periodontology, PRF alone (6 studies; Ib, IIa, IIb) or its combination with biomaterials (6 studies; Ib, IIa, IIb) significantly improved the pocket depth and attachment loss compared to a treatment without PRF. Over 70% of the patients were part of studies with a high level of scientific evidence (randomized and controlled prospective studies). This published evidence (38 articles), with a high scientific level, showed that PRF is a beneficial tool that significantly improves bone and soft tissue regeneration. However, the clinical community requires a standardization of PRF protocols to further examine the benefit of PRF in bone and soft tissue regeneration in reproducible studies, with a higher scientific level of evidence.

Use of Magnifying Loupes among Dental Professionals.

AIM: The study aims to determine the perspective of dental professionals towards magnifying loupes and the selection criteria used while purchasing them. MATERIALS AND METHODS: In this regard, a close-ended questionnaire was structured and distributed among 111 dental professionals. The questionnaire was designed to obtain information regarding the usage of magnifying loupes in dental practices and procedures, limiting factors, and selection criteria for purchasing. The results obtained from this study were statistically analyzed with the help of SPSS. RESULTS: The findings illustrated that most respondents considered the use of magnifying loupes beneficial in dental practices. Also, 20.7% of them preferred "Through-the-Lens" magnifying loupes over "Flip-up" ones. Furthermore, many of the respondents considered that price, magnification, and resolution are the main factors in terms of selection criteria. CONCLUSION: Although, there is an immense growth seen in the usage of magnifying loupes in dentistry; still there is a need to increase the awareness of the dental professionals regarding the positive outcomes of magnification aids in dentistry. CLINICAL SIGNIFICANCE: The study will help enlightening clinicians regarding the selection criteria while purchasing magnifying loupes for dental practices.

[Series: Caries prevention in historical perspective. Education]. / Serie: Cariëspreventie in historisch perspectief. Voorlichting.

In the Netherlands, since the end of the nineteenth century, information has been given to the public about possible ways to prevent dental caries. This happened in the dental offices, in health centres where the parents of young children received advice, and in schools. From 1968 until the mid-1980s, large-scale information campaigns were organised in various municipalities and regions. The Ivory Cross, a Dutch society for oral health education, has been providing information on oral health and supporting the provision of information for, among others, dentists and dental hygienists by offering educational material. The understanding of the phenomenon 'information' has changed during the past century. By applying new insights, there is an increased chance to prevent caries by providing information.

[Wish fulfilling medicine and wish fulfilling dentistry: what does this mean?] / Wensgeneeskunde en wens­tandheelkunde: wat wordt ermee bedoeld?

Wish fulfilling medicine refers to medical procedures applied without a direct medical need. In wish fulfilling medicine, the wish of the patient is dominant, but wish fulfilling medicine is also promoted indirectly by healthcare providers, (pharmaceutical) companies and healthcare insurers. Wish fulfilling medicine often concerns the enhancement of appearance or performance; therefore, wish fulfilling medicine is also referred to as (human) enhancement (therapy). The line between traditional and wish fulfilling medicine is vague: the border between illness and health, normal and abnormal functioning is not sharply defined and is relative to time and place. In the Netherlands, wish fulfilling medicine is not covered in the basic package provided by healthcare insurers and is paid for by the patients themselves. However, 'pay yourself' is not a decisive criterion for wish fulfilling medicine. With new biotechnological developments the domain of wish fulfilling medicine is expanding. Some dental treatments can be considered as wish fulfilling dentistry, for example in the context of cosmetic dentistry, orthodontics, or dental implantology. Although wish fulfilling medical treatments do not cure disease, they can promote health.

Constrained posture in dentistry - a kinematic analysis of dentists.

BACKGROUND: How a dentist works, such as the patterns of movements performed daily, is also largely affected by the workstation Dental tasks are often executed in awkward body positions, thereby causing a very high degree of strain on the corresponding muscles. The objective of this study is to detect those dental tasks, during which awkward postures occur most frequently. The isolated analysis of static postures will examine the duration for which these postures are maintained during the corresponding dental, respectively non-dental, activities. METHODS: 21 (11f/10 m) dentists (age: 40.1 ± 10.4 years) participated in this study. An average dental workday was collected for every subject. To collect kinematic data of all activities, the CUELA system was used. Parallel to the kinematic examination, a detailed computer-based task analysis was conducted. Afterwards, both data sets were synchronized based on the chronological order of the postures assumed in the trunk and the head region. All tasks performed were assigned to the categories "treatment" (I), "office" (II) and "other activities" (III). The angle values of each body region (evaluation parameter) were examined and assessed corresponding to ergonomic standards. Moreover, this study placed a particular focus on static positions, which are held statically for 4 s and longer. RESULTS: For "treatment" (I), the entire head and trunk area is anteriorly tilted while the back is twisted to the right, in (II) and (III) the back is anteriorly tilted and twisted to the right (non-neutral position). Static positions in (I) last for 4-10s, static postures (approx. 60%) can be observed while in (II) and (III) in the back area static positions for more than 30 s are most common. Moreover, in (II) the back is twisted to the right for more than 60 s in 26.8%. CONCLUSION: Awkward positions are a major part of a dentists' work. This mainly pertains to static positions of the trunk and head in contrast to "office work." These insights facilitate the quantitative description of the dentist profession with regard to the related physical load along with the health hazards to the musculoskeletal system. Moreover, the results allow for a selective extraction of the most unfavorable static body positions that dentists assume for each of the activities performed.

Use of traditional herbal medicine as an alternative in dental treatment in Mexican dentistry: a review.

CONTEXT: Herbal therapies are used worldwide to treat health conditions. In Mexico, generations have used them to treat gingivitis, periodontitis, mouth infections, and discoloured teeth. However, few studies have collected scientific evidence on their effects. OBJECTIVE: This study aimed at searching and compiling scientific evidence of alternative oral and dental treatments using medicinal herbs from Mexico. METHODS: We collected various Mexican medicinal plants used in the dental treatment from the database of the Institute of Biology at the National Autonomous University of Mexico. To correlate with existing scientific evidence, we used the PubMed database with the key term '(scientific name) and (oral or dental)'. RESULTS: Mexico has various medical herbs with antibacterial and antimicrobial properties, according to ancestral medicinal books and healers. Despite a paucity of experimental research demonstrating the antibacterial, antimicrobial, and antiplaque effects of these Mexican plants, they could still be useful as an alternative treatment of several periodontal diseases or as anticariogenic agents. However, the number of studies supporting their uses and effects remains insufficient. DISCUSSION AND CONCLUSION: It is important for the health of consumers to scientifically demonstrate the real effects of natural medicine, as well as clarify and establish their possible therapeutic applications. Through this bibliographical revision, we found papers that testify or refute their ancestral uses, and conclude that the use of plants to treat oral conditions or to add to the dental pharmacological arsenal should be based on experimental studies verifying their suitability for dental treatments.

Does California Project the Future of Dentistry?

If trends continue, the majority of U.S. dental students will soon be women. However, there is little empirical analysis examining gender differences in the labor supply of dentists and the potential effects on the dental care sector. We help fill this data void by examining differences in dentists' hours worked by gender, how this has changed over time and the potential implications for the current and future aggregate labor supply of dentists in California.