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1.

Deciphering the molecular determinants of cholinergic anthelmintic sensitivity in nematodes: When novel functional validation approaches highlight major differences between the model Caenorhabditis elegans and parasitic species.

Blanchard, Alexandra; Guégnard, Fabrice; Charvet, Claude L; Crisford, Anna; Courtot, Elise; Sauvé, Christine; Harmache, Abdallah; Duguet, Thomas; O'Connor, Vincent; Castagnone-Sereno, Philippe; Reaves, Barbara; Wolstenholme, Adrian J; Beech, Robin N; Holden-Dye, Lindy; Neveu, Cedric.

PLoS Pathog ; 14(5): e1006996, 2018 05.

Article in English | MEDLINE | ID: mdl-29719008

2.

End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.

Sine, Steven M.

Physiol Rev ; 92(3): 1189-234, 2012 Jul.

Article in English | MEDLINE | ID: mdl-22811427

3.

Binding of Sulfoxaflor to Aplysia californica-AChBP: Computational Insights from Multiscale Approaches.

Alamiddine, Zakaria; Selvam, Balaji; Graton, Jérôme; Laurent, Adèle D; Landagaray, Elodie; Lebreton, Jacques; Mathé-Allainmat, Monique; Thany, Steeve H; Le Questel, Jean-Yves.

J Chem Inf Model ; 59(9): 3755-3769, 2019 09 23.

Article in English | MEDLINE | ID: mdl-31361951

4.

The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.

Bergamin, Elisa; Hallock, Peter T; Burden, Steven J; Hubbard, Stevan R.

Mol Cell ; 39(1): 100-9, 2010 Jul 09.

Article in English | MEDLINE | ID: mdl-20603078

5.

Modified neonicotinoid insecticide with bi-directional selective toxicity and drug resistance.

Zhao, Yuanyuan; Li, Yu.

Ecotoxicol Environ Saf ; 164: 467-473, 2018 Nov 30.

Article in English | MEDLINE | ID: mdl-30144707

6.

AChRs Are Essential for the Targeting of Rapsyn to the Postsynaptic Membrane of NMJs in Living Mice.

Chen, Po-Ju; Martinez-Pena Y Valenzuela, Isabel; Aittaleb, Mohamed; Akaaboune, Mohammed.

J Neurosci ; 36(21): 5680-5, 2016 05 25.

Article in English | MEDLINE | ID: mdl-27225759

7.

Molecular recognition at cholinergic synapses: acetylcholine versus choline.

Bruhova, Iva; Auerbach, Anthony.

J Physiol ; 595(4): 1253-1261, 2017 02 15.

Article in English | MEDLINE | ID: mdl-27779761

8.

Back to the future: Rational maps for exploring acetylcholine receptor space and time.

Tessier, Christian J G; Emlaw, Johnathon R; Cao, Zhuo Qian; Pérez-Areales, F Javier; Salameh, Jean-Paul J; Prinston, Jethro E; McNulty, Melissa S; daCosta, Corrie J B.

Biochim Biophys Acta Proteins Proteom ; 1865(11 Pt B): 1522-1528, 2017 Nov.

Article in English | MEDLINE | ID: mdl-28844740

9.

Evidence of a M₁-muscarinic GPCR homolog in unicellular eukaryotes: featuring Acanthamoeba spp bioinformatics 3D-modelling and experimentations.

Baig, Abdul Mannan; Ahmad, H R.

J Recept Signal Transduct Res ; 37(3): 267-275, 2017 Jun.

Article in English | MEDLINE | ID: mdl-27601178

10.

Functional differences between neurotransmitter binding sites of muscle acetylcholine receptors.

Nayak, Tapan K; Bruhova, Iva; Chakraborty, Srirupa; Gupta, Shaweta; Zheng, Wenjun; Auerbach, Anthony.

Proc Natl Acad Sci U S A ; 111(49): 17660-5, 2014 Dec 09.

Article in English | MEDLINE | ID: mdl-25422413

11.

In Vitro selectivity of an acyclic cucurbit[n]uril molecular container towards neuromuscular blocking agents relative to commonly used drugs.

Ganapati, Shweta; Zavalij, Peter Y; Eikermann, Matthias; Isaacs, Lyle.

Org Biomol Chem ; 14(4): 1277-87, 2016 Jan 28.

Article in English | MEDLINE | ID: mdl-26648135

12.

Antigen-specific immunotherapeutic vaccine for experimental autoimmune myasthenia gravis.

Luo, Jie; Lindstrom, Jon.

J Immunol ; 193(10): 5044-55, 2014 Nov 15.

Article in English | MEDLINE | ID: mdl-25288571

13.

Ion channels gated by acetylcholine and serotonin: structures, biology, and drug discovery.

Wu, Zhong-shan; Cheng, Hao; Jiang, Yi; Melcher, Karsten; Xu, H Eric.

Acta Pharmacol Sin ; 36(8): 895-907, 2015 Aug.

Article in English | MEDLINE | ID: mdl-26238288

14.

Structure and activation of MuSK, a receptor tyrosine kinase central to neuromuscular junction formation.

Hubbard, Stevan R; Gnanasambandan, Kavitha.

Biochim Biophys Acta ; 1834(10): 2166-9, 2013 Oct.

Article in English | MEDLINE | ID: mdl-23467009

15.

Botulinum toxin: application, safety, and limitations.

Bigalke, Hans.

Curr Top Microbiol Immunol ; 364: 307-17, 2013.

Article in English | MEDLINE | ID: mdl-23239359

16.

Structural mechanisms of the agrin-LRP4-MuSK signaling pathway in neuromuscular junction differentiation.

Zong, Yinong; Jin, Rongsheng.

Cell Mol Life Sci ; 70(17): 3077-88, 2013 Sep.

Article in English | MEDLINE | ID: mdl-23178848

17.

Design and control of acetylcholine receptor conformational change.

Jadey, Snehal V; Purohit, Prasad; Bruhova, Iva; Gregg, Timothy M; Auerbach, Anthony.

Proc Natl Acad Sci U S A ; 108(11): 4328-33, 2011 Mar 15.

Article in English | MEDLINE | ID: mdl-21368211

18.

Different magnitude of resistance to non-depolarizing muscle relaxants in dexamethasone-treated rat diaphragm associated with altered acetylcholine receptor expression.

Chen, D; Yang, M R; Huang, L N; Qiu, Y W; Li, S T.

Genet Mol Res ; 13(3): 5892-900, 2014 Aug 07.

Article in English | MEDLINE | ID: mdl-25117347

19.

Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes.

Dallanoce, Clelia; Grazioso, Giovanni; Pomè, Diego Yuri; Sciaccaluga, Miriam; Matera, Carlo; Gotti, Cecilia; Fucile, Sergio; De Amici, Marco.

J Comput Aided Mol Des ; 27(11): 975-87, 2013 Nov.

Article in English | MEDLINE | ID: mdl-24276616

20.

A stepwise mechanism for acetylcholine receptor channel gating.

Purohit, Prasad; Mitra, Ananya; Auerbach, Anthony.

Nature ; 446(7138): 930-3, 2007 Apr 19.

Article in English | MEDLINE | ID: mdl-17443187

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