Use of digital screens by adolescents and association on sleep quality: a systematic review.

This study aimed to analyze the influence of digital screen use on adolescents' quality of sleep. This systematic review was recorded on PROSPERO (CRD42020203403) and conducted according to PRISMA guidelines. Studies covering adolescents from 10 to 19 years were included without language or publication restrictions which answered the following guiding question: "Does the use of digital screen influence adolescents' quality sleep?". Article search included the following databases: (MEDLINE/PubMed), LILACS, SciELO, Scopus, EMBASE, Web of Science, IBECS, Cochrane Library, ClinicalTrials.gov, and Open Gray. The following descriptors were used: "Sleep Quality", "Screen Time", and "Adolescent". The Newcastle-Ottawa Scale (NOS) assessed the methodological quality of the cohort studies, and a modified NOS was used to assess the cross-sectional ones. In total, 2,268 articles were retrieved, of which 2,059 were selected for title and abstract reading, after duplicates were deleted. After this stage, 47 articles were selected for full reading, resulting in the 23 articles which compose this review. Excessive use of digital screens was associated with worse and shorter sleep, showing, as its main consequences, night awakenings, long sleep latency, and daytime sleepiness. The use of mobile phones before bedtime was associated with poor quality of sleep among adolescents. Our evaluation of the methodological quality of the chosen studies found seven to be poor and 16, moderate.

ALDH1 expression and potential clinical implications in chronic inflammatory periapical lesions.

Aldehyde dehydrogenase 1 (ALDH-1) is a marker of stem cells in a variety of diseases, but its role in individuals with chronic inflammatory periapical lesions remains unknown. The aim of this study was to investigate the presence of cells with a stem cell profile based on the immunoexpression of ALDH-1 in periapical granulomas (PGs) and radicular cysts (RCs). A total of 51 cases of periapical lesions (25 PGs and 26 RCs) were subjected to immunohistochemical study. The anti-ALDH-1 antibody was applied using the immunoperoxidase technique. An immunoexpression score (intensity vs. percentage of cells) was used, with the cases being classified as low expression (score: 0 to 4) and high expression (score: 6 to 9). The Chi-square test was used with a 5% level of significance. Immunoexpression of ALDH-1 was detected in all cases of PGs and RCs. In PG cases, the expression was diffuse in connective tissue cells, with most cases exhibiting high expression (n = 18; 69.2%), while in RC cases the expression revealed focal distribution in cells of the capsule and epithelial cells of the cystic lining, with most cases classified as low expression (n = 18; 72%). Significant differences in the expression scores of ALDH-1 were observed in PGs (p = 0.003). The variable expression of ALDH-1 suggests the presence of cells with stem cell profiles in PGs and RCs. These findings suggest that periapical tissues infiltrated by chronic inflammation can recruit important cells for the repair or evolution of periapical lesions.

Oral Health Status and Treatment Needs Among Disabled Children in Recife, Brazil.

PURPOSE: The objective of the present study was to investigate oral health status and treatment needs of children with disabilities in Recife, Brazil. MATERIALS AND METHODS: A cross-sectional study was carried out in the six administrative districts of Recife. The sample consisted of 366 children with disabilities and age between 3 and 12 years. The oral health conditions investigated were dental caries (CPOD index and dmft index), gingival state (IPV and IGC index) and dental trauma. Data analysis involved descriptive statistics, Pearson's chi-square test, Fisher's exact test, and Poisson regression models. RESULTS: The prevalence of caries was 65% and was associated with age (p = 0.0027) and area of residence (p = 0.020). The prevalence of need for treatment was also 65%. The mean decayed, missing and filled teeth (DMFT)/DMFT index of the study population was 3.17/1.73. Their mean number of DMFT was 2.37, 0.55 and 0.25 for the deciduous dentition, as well as 1.56, 0.05 and 0.12 for the permanent dentition. Almost the entire sample (96.7%) had visible plaque, 77.3% had gingival bleeding and 27.6% had dental traumatism. CONCLUSION: Children with disabilities were found to have high rates of caries and gingivitis, as well as cumulative needs for preventive and curative treatment.

Caries experience in children and adolescents with Down Syndrome: A systematic review and meta-analysis.

AIM: This study aimed to perform a systematic review and meta-analysis comparing the prevalence of dental caries in non-syndromic children with children and adolescents with Down syndrome (DS). METHODS: The strategy included a search for articles in electronic databases (MEDLINE via PubMed, Cochrane Library, LILACS, and SciELO). The methods for assessment included the modified Newcastle-Ottawa scale, the methodological quality for cross-sectional studies, and a random-effects meta-analysis model. By obtaining the odds ratio, the tests of heterogeneity and sensitivity were performed. This study includes unpublished data from the cross-sectional study by Paiva et al. (2018), which was conducted in the city of Recife/PE. RESULTS: Twelve cross- section studies met the eligibility criteria and were included in the meta-analysis. Results indicated that children and adolescents with DS had lower caries experience when compared to the non-syndromic ones (95 % CI: 0.22-0.84). The results indicated that the seven studies were statistically significant (p < 0.00001). The risk of bias remained high given that the majority of the studies were cross-sectional reports. CONCLUSION: The results of this study fill the lack of knowledge and indicated that there is scientific evidence to suggest that children and adolescents with Down Syndrome have fewer caries than the non-syndromic group.

Creation of a self-guided course about oral cancer for Community Health Workers: A Teleeducation experience / Criação de um curso autoinstrucional sobre câncer de boca para Agentes Comunitários de Saúde: uma experiência de telemedicina

Abstract Objective: To report the experience of creating and providing a self-instructional course about oral cancer, in a Telehealth platform, to Community Health Workers, and to analyze the participants' clinic and demographic profile. Methods: Descriptive cross-sectional study of development and implementing experience of a course carried on a virtual learning environment, based on ADDIE, an Instructional Design model. The Kolmogorov-Smirnov test was applied, with 95% confidence level for quantitative variables. Results: The initial stage consisted of constructing the online course. In the second stage, the course was provided in a virtual learning environment. The course "Abre a boca, meu povo! - O que você precisa saber sobre o câncer de boca" was provided to the target audience with a student's guide, initial survey, four modules with video lessons, initial and final knowledge test, satisfaction evaluation and certificate. Simplicity, clarity and objectivity have been prioritised in the transmission of knowledge. The final sample comprised 205 Community Health Workers. The predominant profile consisted of professionals aged between 40 and 49 years, female, with more than 10 years of career. Conclusions: The course achieved its objectives, revealing a satisfactory number of professionals in its first edition.

Resumo Objetivo: Relatar a experiência da criação e disponibilização de curso autoinstrucional sobre câncer de boca, em plataforma de Telessaúde, para Agentes Comunitários de Saúde, e analisar o perfil clínico-demográfico dos participantes. Metodologia: Estudo transversal descritivo da experiência de implantação e desenvolvimento de curso realizado em ambiente virtual de aprendizagem, baseado em ADDIE, um modelo de Design Instrucional. Foi aplicado teste de normalidade de Kolmogorov-Smirnov, com 95% de confiança para variáveis quantitativas. Resultados: A primeira fase consistiu na construção do curso on-line. Na segunda fase, o curso foi disponibilizado em ambiente virtual de aprendizagem. O curso "Abre a boca, meu povo! - O que você precisa saber sobre o câncer de boca" foi disponibilizado ao público-alvo com um manual do aluno, enquete inicial, quatro módulos com videoaulas, testes de conhecimentos inicial e final, avaliação de satisfação e certificado. Simplicidade, clareza e objetividade foram priorizadas na transmissão dos conhecimentos. A amostra final foi composta por 205 Agentes Comunitários de Saúde. O perfil predominante foi de profissionais com idade entre 40 e 49 anos, do sexo feminino, com mais de 10 anos de carreira. Conclusões: O curso atingiu os objetivos propostos, revelando um quantitativo satisfatório de profissionais, em sua primeira edição.

Perfil clínico-epidemiológico de pacientes pediátricos de um centro de oncohematologia de pernambuco / Clinical-epidemiological profile of pediatric patients at a center of oncohematology in Pernambuco / Perfil clínico-epidemiológico de pacientes pediátricos en un centro de oncohematología de Pernambuco

ntrodução:O câncer infantojuvenil corresponde a um grupo de várias doenças que têm em comum a proliferação descontrolada de células anormais e que pode ocorrer em qualquer local do organismo. Objetivo:Identificar os tipos de neoplasias mais frequentes na infância e adolescência e analisar o perfil clínico-epidemiológicodos pacientes. Metodologia:Estudo de transversal exploratório, de natureza aplicada com análise documental, realizado no Centro de Oncohematologia Pediátrica do Hospital Universitário Oswaldo Cruz, Recife, Pernambuco.Foram incluídos crianças e adolescentes diagnosticados com neoplasia e tratados por terapia antineoplásica.Os critérios de exclusão foram crianças e adolescentes normorreativas e/ou com doenças sistêmicas; prontuários ilegíveis ou com falta de informações clínicas.Resultados:Identificou-se que 54,21% dos pacientes eram dosexo feminino, seguido por 44,86% do sexo masculino.A faixa etária prevalente no estudo foi o de crianças de 5 a 14 anos (54,21%), ainda sobre o perfil dos pacientes, identificou-se que população autodeclarada como negra foi a mais prevalente representando 44,86% do total, seguido dos brancos com 43,93%. O diagnóstico que prevaleceu foi o de Leucemia Linfoide Aguda(23,36%), seguido pela Retinoblastoma (7,48%) e pela Rabdomiossarcoma embrionário (6,54%), e consequentemente o local da neoplasia primária que prevaleceu foi a Medula óssea (27,10%) seguido do olho (10,28%), deste total nota-se que o tratamento antineoplásico mais utilizado foi a quimioterapia (40,19%) seguido da quimioterapia associada à radioterapia(12,15%) e pela quimioterapia associada a cirurgia (10,28%). Conclusões:A leucemia linfoide aguda foi a neoplasia mais frequente na infância e adolescência, com prevalência na idade entre 5 e 14 anos, no sexo feminino e na etnia negra. A terapia antineoplásica mais utilizada foi a quimioterapia, seguida da associação entre quimioterapia e radioterapia (AU).

Introduction:Childhood cancer correspondsto a group of several diseases that have in common the uncontrolled proliferation of abnormal cells and that can occur anywhere in the body. Objective:Identify the most frequent types of neoplasms in childhood and adolescence and analyze the clinical-epidemiological profile of patients. Methodology:Exploratory cross-sectional study, applied in nature with document analysis, carried out at the Pediatric Oncohematology Center of Oswaldo Cruz University, Recife, Pernambuco. Children and adolescents diagnosed with neoplasia and treated with antineoplastic therapy were included. Exclusion criteria were normoreactive children and adolescents and/or with systemic diseases; illegible medical records or lacking clinical information. Results:It was identified that54.21% of the patients were female, followed by 44.86% male. The prevalent age group in the study was children from 5 to 14 years old (54.21%), still regarding the patients'profile , it was identified that the population self-declared as black was the most prevalent, representing 44.86% of the total, followed by of whites with 43.93%. The diagnosis that prevailed was Acute Lymphoid Leukemia (23.36%), followed by Retinoblastoma (7.48%) and Embryonic Rhabdomyosarcoma (6.54%), and consequently,the site of the primary neoplasm that prevailed was Bone marrow (27.10%) followed by the eye (10.28%), of this total it is noted that the most used anticancer treatment was chemotherapy (40.19%) followed by chemotherapy associated with radiotherapy (12.15% ) and chemotherapy associated with surgery (10.28%). Conclusions:Acute lymphoblastic leukemia was the most frequent neoplasm in childhood and adolescence, with a prevalence between 5 and 14 years of age, in females,and black ethnicity. The most used antineoplastic therapy was chemotherapy, followed by the association between chemotherapy and radiotherapy (AU).

ntroducción: El cáncer infantil corresponde a un grupo de varias enfermedades que tienen en común la proliferación descontrolada de células anormales y que pueden presentarse en cualquier parte del cuerpo. Objetivo: Identificar los tipos de neoplasias más frecuentes en la infancia y la adolescencia y analizar el perfil clínico-epidemiológico de los pacientes. Metodología: Estudio transversal exploratorio, aplicado en la naturaleza con análisis de documentos, realizado en el Centro de Oncohematología Pediátrica del Hospital Universitario Oswaldo Cruz, Recife, Pernambuco. Se incluyeron niños y adolescentes con diagnóstico de neoplasia y tratados con terapia antineoplásica. Los criterios de exclusión fueron niños y adolescentes normorreactivos y/o con enfermedades sistémicas; registros médicos ilegibles o carentes de información clínica. Resultados: Se identificó que el 54,21% de los pacientes eran del sexo femenino, seguido del 44,86% del masculino. El grupo etario prevalente en el estudio fueron los niños de 5 a 14 años (54,21%), en cuanto al perfil de los pacientes, se identificó que la población autodeclarada afrodescendiente fue la más prevalente, representando el 44,86% del total, seguido de los blancos con un 43,93%. El diagnóstico que predominó fue Leucemia Linfoide Aguda (23,36%), seguido de Retinoblastoma (7,48%) yRabdomiosarcoma Embrionario (6,54%), y en consecuencia el local de la neoplasia primaria que predominó fue Médula Ósea (27,10%) seguido de ocular (10,28%), de este total se destaca que el tratamiento anticancerígeno más utilizado fue la quimioterapia (40,19%) seguida de la quimioterapia asociada a radioterapia (12,15%) y la quimioterapia asociada a cirugía (10,28%). Conclusiones: La leucemia linfoblástica aguda fue la neoplasia más frecuente en la infancia y la adolescencia, con prevalencia entre los 5 y los 14 años, en el sexo femenino y en la etnia negra. La terapia antineoplásica más utilizada fue la quimioterapia, seguida de la asociación entre quimioterapia y radioterapia (AU).

Non-Invasive Methods and the Use of Infiltrating Resins for the Control of Caries Progression in Deciduous Teeth: A Systematic Review and Meta-Analysis

ABSTRACT Objective: To evaluate the influence of non-invasive treatment associated with the use of infiltrating resin for managing caries lesions in primary teeth. Material and Methods: A systematic review was performed by selecting articles from 6 online databases, using a search algorithm and eligibility criteria for data extraction and data synthesis for the papers included. Clinical trials involving primary teeth with incipient caries lesions (1/2 of the enamel or 1/3 of the outer dentin) were included, presenting full text and answering the study's guiding question. This study used the RoB 2 tool for the risk of bias assessment and GRADE for certainty of evidence. Random effects meta-analyses were implemented, and lesion progression treatment effects were estimated through relative risk (RR) and associated 95% confidence intervals. Results: A total of 440 studies were found. After analyzing the inclusion criteria and removal of duplicates, eight studies were analyzed for quality evidence. Five of the eight studies included in this review contributed to the meta-analysis, all with some reflections regarding the risk of bias. Overall, the results of the meta-analysis showed that non-invasive treatment, when associated with the use of infiltrating resins, significantly reduced the risk of caries progression in relation to the treatment without this addition for follow-up periods ranging from 12 months to 2 years (RR 0.51 [0.40-0.65]). Conclusion: There is moderate certainty of evidence that the use of infiltrating resins associated with non-invasive treatments decreases the risk of caries progression in primary teeth with incipient caries lesions (1/2 of the enamel or 1/3 of the dentin outer) when combined with non-invasive control methods alone.

Educação sexual: dificuldades dos pais de jovens com síndrome de down / Sex education: difficulties for parents of young people with down syndrome / Educación sexual: dificultades para los padres de jóvenes con síndrome de down

Com este estudo buscou-se conhecer as dificuldades e barreiras de pais na educação sexual de jovens com Síndrome de Down, a partir de uma pesquisa descritiva e de natureza qualitativa, utilizando-se o conceito das representações sociais como referencial teórico-metodológico. O estudo foi conduzido em uma Organização Não Governamental (ONG), localizada em Recife (PE), após aprovação do Comitê de Ética e Pesquisa, sob parecer consubstanciado 3.558.587. A amostra do estudo envolveu 11 pais de jovens com Síndrome de Down com idades entre 15 e 24 anos. A coleta de dados foi realizada por meio de entrevistas semiestruturadas. A abordagem escolhida para a interpretação desses dados foi a análise de conteúdo proposta por Bardin. Pode-se elencar como principais dificuldades enfrentadas pelos pais ao conversarem com seus filhos sobre sexualidade: a infantilização do jovem com Síndrome de Down, julgando-o incapaz de experienciar tais fenômenos e compreender a orientação que pudesse ser repassada; o medo em ultrapassar etapas e, de repente, "estimular" o filho a viver sua sexualidade de maneira "precoce"; e o fato de os pais também terem recebido pouca ou nenhuma orientação sexual por parte de suas famílias. Diante das narrativas dos pais, é possível perceber que ainda são muitos os mitos, tabus e preconceitos que permeiam a sexualidade dos jovens com Síndrome de Down, demonstrando que os responsáveis estão despreparados para dar as devidas orientações.(AU)

This study sought to know the difficulties and barriers of parents in the sexual education of young people with Down Syndrome, from a descriptive, qualitative study, using the concept of social representations as a theoretical-methodological framework. The study was conducted in a Non-Governmental Organization (NGO), located in Recife (PE) after approval by the Ethics and Research Committee, under substantiated opinion 3,558,587. The study sample involved 11 parents of young people with Down Syndrome aged between 15 and 24 years. The data collection was carried out by using semi-structured interviews. The approach chosen for interpretation of these data was the content analysis proposed by Bardin. The main difficulties faced by parents in talking with their children about sexuality can be listed as: the infantilization of young persons with Down Syndrome, deeming them incapable of experiencing such phenomena and understanding the guidance that could be given; the fear of overshooting the stages and, suddenly, "stimulating" the child to live their sexuality in an "early" way; and the facts of the parents also having received little or no sexual guidance from their families. Given the parents' narratives, it is possible to realize that there are still many myths, taboos, and prejudices that permeate the sexuality of young people with Down Syndrome, demonstrating that parents were unprepared to provide the right guidance.(AU)

Este estudio buscó conocer las dificultades y barreras de los padres en la educación sexual de los jóvenes con síndrome de Down a partir de un estudio descriptivo, cualitativo, que utilizó el concepto de representaciones sociales como marco teórico-metodológico. La investigación se llevó a cabo en una Organización No Gubernamental (ONG), ubicada en la ciudad de Recife (Pernambuco, Brasil), después de la aprobación del Comité de Ética e Investigación, bajo la opinión fundamentada 3.558.587. La muestra del estudio incluyó a 11 padres de jóvenes con síndrome de Down con edades comprendidas entre 15 y 24 años. La recolección de datos se realizó mediante entrevista semiestructurada. El enfoque elegido para la interpretación de los datos fue el análisis de contenido propuesto por Bardin. Pueden enumerarse como las principales dificultades que enfrentan los padres para hablar sobre la sexualidad con sus hijos: la infantilización del joven con síndrome de Down, considerándolo incapaz de experimentar tales fenómenos y comprender la orientación que se le puede dar; el miedo de ir más allá de las etapas y, de repente, "estimular" al niño a vivir su sexualidad de una manera "temprana"; y el hecho de que los padres también habían recibido poca o ninguna orientación sexual de sus familias. Dadas las narraciones de los padres, es posible darse cuenta de que todavía hay muchos mitos, tabúes y prejuicios sobre la sexualidad de los jóvenes con síndrome de Down, lo que muestra que los padres no estaban preparados para brindarles este tipo de orientación.(AU)

Use of digital screens by adolescents and association on sleep quality: a systematic review / Uso de telas digitais por adolescentes e associação com a qualidade do sono: uma revisão sistemática / Uso de pantallas digitales por adolescentes y asociación con la calidad del sueño: una revisión sistemática

This study aimed to analyze the influence of digital screen use on adolescents' quality of sleep. This systematic review was recorded on PROSPERO (CRD42020203403) and conducted according to PRISMA guidelines. Studies covering adolescents from 10 to 19 years were included without language or publication restrictions which answered the following guiding question: "Does the use of digital screen influence adolescents' quality sleep?". Article search included the following databases: (MEDLINE/PubMed), LILACS, SciELO, Scopus, EMBASE, Web of Science, IBECS, Cochrane Library, ClinicalTrials.gov, and Open Gray. The following descriptors were used: "Sleep Quality", "Screen Time", and "Adolescent". The Newcastle-Ottawa Scale (NOS) assessed the methodological quality of the cohort studies, and a modified NOS was used to assess the cross-sectional ones. In total, 2,268 articles were retrieved, of which 2,059 were selected for title and abstract reading, after duplicates were deleted. After this stage, 47 articles were selected for full reading, resulting in the 23 articles which compose this review. Excessive use of digital screens was associated with worse and shorter sleep, showing, as its main consequences, night awakenings, long sleep latency, and daytime sleepiness. The use of mobile phones before bedtime was associated with poor quality of sleep among adolescents. Our evaluation of the methodological quality of the chosen studies found seven to be poor and 16, moderate.

Este estudo buscou analisar a influência do uso de telas digitais na qualidade do sono de adolescentes. Esta revisão sistemática foi registrada no PROSPERO (CRD42020203403) e realizada de acordo com as diretrizes do PRISMA. Foram incluídos estudos que abrangem a faixa etária de 10 a 19 anos sem restrição de idioma ou data de publicação e que responderam à seguinte pergunta condutora: "O uso da tela digital influencia a qualidade do sono dos adolescentes?". A busca por artigos incluiu as seguintes bases de dados: (MEDLINE/PubMed), LILACS, SciELO, Scopus, EMBASE, Web of Science, IBECS, Cochrane Library, ClinicalTrials.gov e Open Gray. Os descritores utilizados foram "Qualidade do Sono", "Tempo de Tela" e "Adolescente". A Escala de Newcastle-Ottawa (NOS) foi utilizada para avaliar a qualidade metodológica dos estudos de coorte e a escala NOS modificada foi usada para avaliar os estudos transversais. Foram encontrados 2.268 artigos, dos quais 2.059 foram selecionados para leitura de títulos e resumos após a exclusão das duplicatas. Foram então selecionados 47 artigos para leitura na íntegra, dos quais 23 foram escolhidos para compor esta revisão. O uso excessivo de telas digitais foi associado à má qualidade e menor duração do sono, apresentando como principais consequências despertares noturnos, maior latência do sono e sonolência diurna. Ademais, o uso do celular antes de dormir foi associado à má qualidade do sono em adolescentes. A avaliação da qualidade metodológica classificou sete estudos como sendo de baixa qualidade e 16 de qualidade moderada. Concluímos que o uso de telas digitais influenciou a qualidade do sono dos adolescentes.

Este estudio buscó analizar la influencia del uso de pantallas digitales en la calidad del sueño de los adolescentes. Esta revisión sistemática se registró en PROSPERO (CRD42020203403) y se realizó de acuerdo con los lineamientos de PRISMA. Se incluyeron los estudios en que participaron el grupo etario entre los 10 y los 19 años, sin restricción de idioma o fecha de publicación, y que respondieran a la siguiente pregunta orientadora: "¿El uso de la pantalla digital influye en la calidad del sueño de los adolescentes?". La búsqueda de artículos se realizó en las siguientes bases de datos: (MEDLINE/PubMed), LILACS, SciELO, Scopus, EMBASE, Web of Science, IBECS, Cochrane Library, ClinicalTrials.gov y Open Gray. Los descriptores utilizados fueron "Calidad del sueño", "Tiempo de pantalla" y "Adolescente". Se utilizaron la Escala Newcastle-Ottawa (NOS) para evaluar la calidad metodológica de los estudios de cohortes y la NOS modificada para evaluar los estudios transversales. Del total de 2.268 artículos encontrados, se seleccionaron 2.059 para la lectura de títulos y resúmenes después de excluidos los duplicados. Luego se seleccionaron 47 artículos para lectura completa, de los cuales 23 fueron elegidos para componer esta revisión. El uso excesivo de las pantallas digitales estuvo asociado con la mala calidad y menor duración del sueño, teniendo como principal consecuencia los despertares nocturnos, el aumento de la latencia del sueño y la somnolencia diurna. Además, el uso del teléfono celular antes de acostarse se asoció con una mala calidad del sueño en los adolescentes. La evaluación de la calidad metodológica clasificó siete estudios como de baja calidad y 16 como de calidad moderada. Se concluyó que el uso de las pantallas digitales influye en la calidad del sueño de los adolescentes.

ALDH1 expression and potential clinical implications in chronic inflammatory periapical lesions

Abstract: Aldehyde dehydrogenase 1 (ALDH-1) is a marker of stem cells in a variety of diseases, but its role in individuals with chronic inflammatory periapical lesions remains unknown. The aim of this study was to investigate the presence of cells with a stem cell profile based on the immunoexpression of ALDH-1 in periapical granulomas (PGs) and radicular cysts (RCs). A total of 51 cases of periapical lesions (25 PGs and 26 RCs) were subjected to immunohistochemical study. The anti-ALDH-1 antibody was applied using the immunoperoxidase technique. An immunoexpression score (intensity vs. percentage of cells) was used, with the cases being classified as low expression (score: 0 to 4) and high expression (score: 6 to 9). The Chi-square test was used with a 5% level of significance. Immunoexpression of ALDH-1 was detected in all cases of PGs and RCs. In PG cases, the expression was diffuse in connective tissue cells, with most cases exhibiting high expression (n = 18; 69.2%), while in RC cases the expression revealed focal distribution in cells of the capsule and epithelial cells of the cystic lining, with most cases classified as low expression (n = 18; 72%). Significant differences in the expression scores of ALDH-1 were observed in PGs (p = 0.003). The variable expression of ALDH-1 suggests the presence of cells with stem cell profiles in PGs and RCs. These findings suggest that periapical tissues infiltrated by chronic inflammation can recruit important cells for the repair or evolution of periapical lesions.

Levantamento de dados secundários de anomalias dentárias em crianças atendidas na Faculdade de Odontologia de Pernambuco / Survey of secondary data of dental anomalies in children attended at the Pernambuco Dentistry Faculty

Os distúrbios de crescimento e desenvolvimento dos dentes são alterações no número, tamanho ou forma dos dentes com origem multifatorial, sendo o objetivo desse estudo conhecer a frequência de anomalias dentárias. Trata-se de uma pesquisa quantitativa, descritiva e com delineamento transversal de dados secundários, utilizando registros dos prontuários de crianças dos 3 aos 12 anos de idade atendidas na Clínica de Atenção Básica Infantil da FOP/UPE. Foram coletadas informações referentes ao sexo, idade, presença, tipo e localização da anomalia. Realizamos uma análise estatística utilizando o Microsoft Excel e Epi Info v.3.5.3. O estudo teve uma amostra final de 197 prontuários, 52,8% do sexo feminino e 47,2% do sexo masculino. Foram identificadas 4,5% anomalias dentárias, sendo (77,8%) anomalia de número, localizada na região anterior (88,8%). A predominância foi maior no sexo feminino (N=6). As anomalias dentárias presentes foram: anodontia (55,5%), dentes supranumerários (22,3%), giroversão (11,1%) e fusão (11,1%). A frequência de anomalia dentária foi de 4,5%, sendo a anomalia de número mais frequente (77,8%), acometendo mais o sexo feminino e com média de idade de 8,5 anos... (AU)

Tooth growth and development disorders are changes in the number, size or shape of teeth with multifactorial origin, and the aim of this study is to know the frequency of dental anomalies. This is a quantitative, descriptive and cross-sectional study of secondary data, using records from the medical records of children aged 3 to 12 years attended at the Primary Child Care Clinic of FOP/UPE. Information regarding gender, age, presence, type and location of the anomaly was collected. We performed a statistical analysis using Microsoft Excel and Epi Info v.3.5.3. The study had a final sample of 197 medical records, 52.8% female and 47.2% male. 4.5% dental anomalies were identified, (77.8%) number anomaly, located in the anterior region (88.8%). Predominance was higher in females (N=6). The dental anomalies were: anodontics (55.5%), supernumerary teeth (22.3%), gyroversion (11.1%) and fusion (11.1%). The frequency of dental anomaly was 4.5%, being the most frequent number anomaly (77.8%), affecting the female sex more and with a mean age of 8.5 years... (AU)

Parents' knowledge about the oral health care of oncological children / Conhecimento dos pais de crianças oncológicas em saúde bucal

ABSTRACT Objective: identifying the parents/guardians' knowledge about the oral health condition of oncological children assisted at the Pediatric Oncology Department of the Institute of Integral Medicine Professor Fernando Figueira. Methods: A cross-sectional study comprising a sample of 163 parents/guardians of children assisted at the Pediatric Oncology Department of the IIMP in the city of Recife, Pernambuco, applying a semi-structured form, tested with 10% of the sample in a pilot study. Results: Most of the parents/guardians were female subjects (87%) and patients' mothers (81%), between 25 and 34 years of age (44.8%), with a family income of a minimum wage (47%), educational level until elementary school (51.6%) and from the countryside of the state of Pernambuco (56%). Most of the children were male subjects (58.9%) with average age of 7.57 years, who had attended or stopped primary school (54.6%) and had been diagnosed with Acute Lymphoblastic Leukemia (57.7%) and treated with chemotherapy (92.6%). All parents considered important to have dental surgeons in the oncology department assisting the children in their oral hygiene. More than half of these parents reported knowing about how to avoid caries (63%) and, almost half of the children had never had a consultation with a dentist before (41.1%). Conclusion: Parents/guardians have information about oral health care, but they do not put it into practice.

RESUMO Objetivo: Identificar o conhecimento dos pais/responsáveis de crianças oncológicas sobre os cuidados de saúde bucal dedicados aos seus filhos acompanhados na oncologia pediátrica do Instituto de Medicina Integral Prof. Fernando Figueira. Métodos: Estudo transversal, com amostra de 163 Pais/responsáveis de crianças acompanhadas pelo Setor de Oncologia Pediátrica do IMIP na cidade do Recife/PE através da aplicação de formulário semiestruturado, testado com 10% da amostra em um estudo-piloto. Resultados: Os pais/responsáveis em sua maioria pertenciam ao sexo feminino (87%), eram mães dos pacientes (81%), com idade entre 25 a 34 anos (44,8%), com renda familiar de um salário mínimo (47%), com escolaridade até o ensino fundamental (51,6%) e do interior do Estado de Pernambuco (56%). As crianças na maior parte eram do sexo masculino (58,9%) e tinha idade média de 7, 57 anos, cursavam ou haviam parado de estudar no ensino fundamental (54,6%), foram diagnosticados com Leucemia Linfóide Aguda (57,7%) e tratados através de quimioterapia (92,6%). Todos os pais consideravam importante a presença do cirurgião dentista no Setor de Oncologia e realizavam a higiene bucal da criança, mais da metade afirmaram ter conhecimento sobre como evitar a cárie (63%) e quase metade das crianças nunca foram ao dentista (41,1%). Conclusão: Os pais/responsáveis possuem conhecimento sobre saúde bucal, mas não colocam em prática.

Reconstrução de lesão em lábio superior por mordedura animal em criança / Reconstruction for injury in upper lip biting in animal in child

Os ferimentos ocasionados por mordeduras animais são comuns e de importância na saúde pública, tendo consequências, como desfiguração, infecção e, até mesmo, a morte em casos mais graves. A conduta frente a essas lesões é controversa, principalmente do ponto de vista do fechamento primário da ferida da profilaxia de doenças infecto-contagiosas, originadas a partir do contato da saliva do animal com a ferida. O atendimento desses doentes na urgência consiste no controle da infecção, reabilitação funcional e, consequentemente, estética, a fim de minimizar danos psíquicos e possibilitar retorno ao convívio social. O presente trabalho relata o caso de ferimento em lábio superior de uma criança decorrente de agressão por mordida canina. A reconstrução foi realizada através da rotação de retalho rombóide da mucosa oral bem como do avanço retilíneo do retalho cutâneo associado aos triângulos de Descarga. Além disso, foi instituída uma antibioticoterapia específica. Dessa maneira, foi obtido um resultado estético e funcional satisfatório, sem complicações infecciosas pós-operatórias ou deiscências de suturas... (AU)

Injuries caused by dog bites are common and have importance in public health, with consequences such as disfigurement, infection and even death in severe cases. The correct approach to these lesions is controversial, especially in primary closure of the point of view of the wound and prophylaxis of infectious diseases originating from the animal's saliva contact with the wound. The care of these patients in the emergency consists in controlling infection, functional rehabilitation and consequently aesthetics in order to minimize possible psychological damage and return to social life. This paper reports the injury case in upper lip of a child resulting from aggression by canine bite. The reconstruction was carried out by retail rhomboid oral mucosa rotation and straight forward skin flap associated with the discharge of triangles. Moreover, a particular antibiotic was introduced. Thus it was obtained a satisfactory aesthetic and functional results without infectious postoperative complications or dehiscence of sutures... (AU)

Clinical aspects in the treatment planning for rehabilitation with overdenture and protocol-type prosthesis / Aspectos clínicos utilizados no planejamento de prótese overdenture e protocolo

Objective: The aim of this study was to criticaly review the published literature regarding the clinical aspects involved in the rehabilitation of edentulous patients using Branemark protocol and overdenture prostheses.Methods: An active search was conducted in the LILACS, MEDLINE, PubMed, and SciELO databases using the descriptors: "Coating for dentures" (Overlay Prosthesis and Overdenture) and "Implant-supported fixed dental prosthesis" (Protesis dental de suporte implantado, Dental prosthesis, and Implant Supported Prosthesis) in Portuguese, English, and Spanish between January 2000 and October 2014.Results: The following parameters should be considered when selecting between Branemark protocol and overdenture prostheses: bone support, lip support, lip-line, upper lip length, oral mucosa conditions and size, alveolar ridge contour, crown-bone ratio, interarch space, and speaking space. Overdenture rehabilitation can provide many benefits to patients, such as prosthetic retention, stability, comfort, and improved aesthetics.Conclusions: This study highlights the need for a thorough individualized treatment planning to ensure that fixed prostheses and overdentures have an excellent prognosis when used appropriately in suitable patients at the appropriate time.

Objetivo: Verificar por meio de revisão crítica da literatura os aspectos clínicos durante o planejamento de pacientes edêntulos frente à utilização de próteses tipo protocolo de Branemark e overdenture.Métodos: Busca ativa nas bases de dados LILACS, MEDLINE, PubMed e SciELO por meio dos descritores: "Revestimento de dentadura" (Prótese de Recobrimento e Overdenture) e "Prótese dentária fixada por implante" (Protesis dental de suporte implantado e Dental prosthesis, implant supported) entre janeiro de 2000 até outubro de 2014 nas línguas Portuguesa, Inglesa e Espanhola.Resultados: Deve-se levar em consideração para indicar as próteses overdentures e protocolo o suporte ósseo, suporte labial, linha do sorriso, comprimento do lábio superior, qualidade e quantidade da mucosa, contorno do rebordo alveolar, relação coroa/osso, espaço interarcos e zona fonética. A reabilitação com overdenture pode trazer muitos benefícios ao paciente, tais como retenção, estabilidade, conforto, e a estética.Conclusões: Evidencia-se a necessidade de um planejamento individualizado, para que se chegue a um correto plano de tratamento, no qual as próteses fixas e overdentures possam ter um excelente prognóstico, desde que utilizadas no momento apropriado e no paciente indicado.

Correlação do Papilomavírus Humano com o Carcinoma Epidermoide Bucal: revisão sistemática / Correlation of Human Papillomavirus with Oral squamous cell carcinoma: Systematic Review

Objetivo: Verificar através de revisão sistemática da literatura a correlação entre o Papilomavírus Humano (HPV) e o Carcinoma Epidermóide Bucal. Método: Busca ativa nas bases de dados LILACS, MEDLINE, PubMed e SciELO através dos descritores: "Carcinoma Epidermóide Bucal" (Oral carcinomas e carcinoma oral de células escamosas) e "Papilomavírus Humano" (Human Papillomavirus e Virus del Papiloma Humano) entre janeiro de 2000 até fevereiro de 2014 nas línguas Portuguesa, Inglesa e Espanhola. Resultados: Nos estudos analisados, o tipo de HPV mais prevalente é o de baixo risco (6 e 54) e o de alto risco (16), sendo encontrado em lesões localizadas na língua e assoalho de boca em pacientes do sexo masculino, faixa etária acima de 60 anos e não-tabagistas. Conclusões: São necessários estudos que permitam considerar o HPV como agente causal do carcinoma epidermoide bucal, pois, na literatura, a presença de diversos carcinógenos, atuando concomitantemente, impede conclusões precisas e apontam para uma ação sinérgica do HPV com outros carcinógenos que, de fato, potencializaria o desenvolvimento de uma neoplasia maligna... (AU)

Objective: To determine through a systematic review of the literature the correlation between the Human Papillomavirus (HPV) and oral squamous cell carcinoma . Method: Active search in the databases LILACS, MEDLINE , PubMed and SciELO using the descriptors : "Oral squamous cell carcinoma" and " Human Papillomavirus " between January 2000 until February 2014 in Portuguese, English and Spanish . Results: In the studies reviewed, the most prevalent type of HPV is low risk (6 e 54) and high risk (16), being found in lesions on the tongue and floor of mouth in male patients , age over 60 years and nonsmokers. Conclusions: Studies are needed that allow consider HPV as the causative agent of oral squamous cell carcinoma, because in the literature the presence of several carcinogens , acting concurrently , prevents accurate conclusions and point to a synergistic action between HPV and other carcinogens that actually potentiate developing a malignancy... (AU)

Fratura de mandíbula durante exodontia de terceiro molar inferior incluso: relato de caso / Fractured mandible during impacted third molar exodontia: a case report

Introdução: Os terceiros molares inferiores apresentam maior prevalência de inclusão. Quando indicada, a exodontia desses dentes pode resultar em complicações, como as fratura mandibular. Objetivo: relatar um caso clínico de fratura de mandibular que ocorreu e foi diagnosticada durante exodontia do terceiro molar inferior incluso e tratado com sucesso por método conservador. Relato de caso: paciente submetido a procedimento cirúrgico sob anestesia local para extração do dente 48 que se encontrava na posição 1B, segundo Pell e Gregory. O acesso cirúrgico foi realizado através de uma incisão do tipo Maurel e por ostectomia periférica com broca cirúrgica 702, realizando movimentos de alavanca com elevador reto. A fratura mandibular foi detectada no momento da exérese do dente em questão. O tratamento adotado foi conservador, sendo realizado a osteossíntese, além de bloqueio maxilo-mandibular com amarrias do tipo Gilmer Sauer. Após uma semana, o bloqueio foi removido e a oclusão checada. Considerações finais: As complicações em exodontias são sempre um fator que se deve ponderar ao planejar uma cirurgia. A fratura mandibular neste caso foi tratada... (AU)

Introduction: The third molars have a higher prevalence of impaction. When indicated, the extraction of these teeth can result in complications such as fracture mandibular. Objective: To report a case of mandibular fracture that occurred and was identified during the extraction of inferior impacted third molar, and successfully treated by a conservative method. Case report: The patient underwent surgical procedure under local anesthesia for the extraction of tooth 48 which was in position 1B, according to Pell and Gregory. Surgical access was performed through a Maurel type incision and peripheral ostectomy with surgical drill 702, executing lever movements with a straight elevator. The mandibular fracture was detected at the time of removal of the tooth in question. A conservative treatment was adopted, as osteosynthesis and maxillomandibular block with Gilmer Sauer type amarrias were performed. After one week, the maxillomandibular block was removed and the dental occlusion was checked. Final Thoughts: Complications in extractions are always to be considered when planning a surgery. The mandibular fracture in this case was handled... (AU)