Anal Metastasis from Lung Cancer: Report of a Case and Systematic Review of the Literature.

Background: Lung cancer is the most frequent cancer, accounting for over 2 million new cases per year worldwide. In Romania, the cancers with the highest incidence are lung cancer for men and breast cancer for women. Cancer-related deaths follow the same pattern. More than 50% of the patients with lung cancers have distant metastases at the time of diagnosis. Metastases from lung cancer occur mainly in the brain, bones, liver, and adrenals. Anal metastases from primary lung cancer are extremely uncommon. As far as we know there are only 12 cases reported in the literature until now. Case report: Case report and systematic review. We performed a systematic literature search in PubMed using the following MeSH terms: "lung cancer metastasis" AND "anal" OR "anus" OR "perianal". The search was conducted from the beginning of the database onwards. No language exclusion criteria were used. We report the case of a patient with advanced lung adenocarcinoma presenting with a painful, ulcerated and bleeding anal tumor. The anal tumor was excised with primary wound closure in spinal anesthesia. The pathology report and the immunohistochemistry of the specimen revealed metastasis of the lung adenocarcinoma. The review included 12 papers reporting 12 cases. The male/female ratio was 3/1. The average age was 62,16 years. Among these 12 patients, one had a SCLC. From the remaining 11 cases with NSCLC, 4 were adenocarcinomas, 4 squamous cell carcinomas, two anaplastic carcinomas and one mucoepidermoid carcinoma. The anal metastases were synchronous in 4 cases and metachronous in the rest of 8 cases. Since 2006 immuno-histochemistry plays an important role in the diagnosis of these metastases. Conclusions: Our patient presented an anal metastasis of a lung adenocarcinoma that was masquerading as a complicated hemorrhoidal disease. Because anal masses can be easily misdiagnosed, patients with lung cancers and anal or perianal complaints should be evaluated for metastatic disease. Medical teams that are managing such cases must be aware of this rare but possible situation. Immunohistochemistry plays an important role in establishing the diagnosis for the anal or perianal tumours in patients with lung cancer.

[Anthropological study on hearing deficit]. / Cercetari antropologice asupra unui lot de deficienti auditivi.

UNLABELLED: Professional training of hearing impaired persons is conditioned by the stage of psychologic development and by educational level. MATERIAL AND METHOD: The study was carried out on a series of 142 children (87 girls and 55 boys) aged 12 to 17 years with hearing deficit from a special school for deaf. RESULTS: The distribution of these children according to their parents being deaf or not, skills, constitution, intensity of voice was analyzed. The goal of this study is to demonstrate that students in these special schools have to get full support for participating in joint activities with hearing students. Such activities are favorable not only for developing mutual interests, but also for improving verbal expression in a new, pleasant, lively and instructive.

Fractal analysis of palmar electronographic images. Medical anthropological perspectives.

The present paper brings to the medical specialists' attention a possibility of multivalent imagistic investigation--the palmar electrographic method submitted to a totally new analysis by the fractal method. Its support for information recording is the radiosensitive film. This makes it resemble the radiological investigation, which opened the way of correlating the shape of certain structures of the organism with their function. By the specific electromagnetic impressing of the ultra photosensitive film, palmar electrography has the advantage of catching the shape of certain radiative phenomena, generated by certain structures in their functional dynamics--at the level of the human palmar tegument. This makes it resemble the EEG, EKG and EMG investigations. The purpose of this presentation is to highlight a new modality of studying the states of the human organism in its permanent adaptation to the living environment, using a new anthropological, informational vision--by fractal processing and by the couple of concepts system / interface--much closer to reality than the present systemic thinking. The human palm, which has a special medial-anthropological relevance, is analysed as a complex adaptive biological and socio-cultural interface between the internal and external environment. The fractal phenomena recorded on the image are ubicuitary in nature and especially in the living world and their shapes may he described mathematically and used for decoding their informational laws. They may have very useful implications in the medical act. The paper presents a few introductory elements to the fractal theory, and, in the final part, the pursued objectives are concretely shown by grouping the EG images according to certain more important medical-anthropological themes.

[The medical and social impact of the gross domestic product on the life expectancy and infantile mortality in Romania]. / Impactul medico-social al nivelului pib asupra sperantei de viata si a mortalitatii infantile în Romania.

In this study we have analyzed the correlations between the GDP reported on every inhabitant and the life expectancy respective the infantile mortality rates. Analysis cover 11 countries, divided in four categories: three former countries members of EU (France, Italy, Sweden), three countries recently admitted (2004) in E.U. (Poland, Slovenia, Hungary), two countries which will join E.U. in 2007 and other three countries none located in Europe (Canada, Japan, USA). In the countries that invest a lot in health care system the life expectancy at birth is bigger that in other countries, but this relation is not a linear one. Infantile mortality in modern society is strongly influenced by the socio-economic status.