RESUMEN
BACKGROUND: Kidney transplantation is the treatment of choice for end-stage renal disease that restores the patients' quality of life and reduces the morbidity and mortality rates induced by renal failure and its complications. However, after transplantation the organ and patient survival rates are important issues of interest in many centers worldwide. SUBJECTS AND METHODS: This is a historical cohort study planned to determine the organ survival rate after kidney transplantation from deceased donor during a period of 10 years (March 1999-March 2009) in Shiraz Transplant Center, Namazi Hospital, Shiraz, Iran. We tried to clarify the probable contributory risk factors implicating in graft loss. Kaplan-Meier method was used to determine the survival rate. Log-rank test was used to compare survival curves, and Cox regression model to define the hazard ratio and for modeling of factors implicating in survival rate. RESULTS: Mean follow-up period was 37.54 +/- 28.6 months. Allograft survival rates at 1, 3, 5, and 9 years after kidney transplantation from deceased donor (calculated by Kaplan-Meier method) was found to be 93.7, 89.1, 82.1, and 80.1%, respectively. Duration of dialysis before operation and creatinine level at discharge were showed to be the most important factors influencing survival rate of renal allograft. CONCLUSION: Overall long-term graft survival in our cohort is satisfactory and comparable with reports from large centers in the world. Duration of dialysis before operation and creatinine level at discharge are the only independent factors that could correlate with long-term graft survival in our cohort.
Asunto(s)
Supervivencia de Injerto , Trasplante de Riñón , Adolescente , Adulto , Anciano , Cadáver , Niño , Preescolar , Estudios de Cohortes , Creatinina/análisis , Femenino , Humanos , Terapia de Inmunosupresión/métodos , Lactante , Irán/epidemiología , Trasplante de Riñón/mortalidad , Tiempo de Internación/estadística & datos numéricos , Masculino , Persona de Mediana Edad , Modelos de Riesgos Proporcionales , Diálisis Renal/estadística & datos numéricos , Factores de Riesgo , Tasa de SupervivenciaRESUMEN
This is a cross-sectional and analytical-descriptive study of 511 children less than 36 months of age who were admitted to Tabriz Children's Hospital with acute gastroenteritis during a period of 2 years (from October 2007 to October 2009). Rotavirus was found in stool specimens of 284 (55.6%) of 511 children with diarrhea. Two-thirds of them were admitted during autumn and winter for a mean hospital stay of 3.1 ± 1.8 days.