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1.
Opt Express ; 30(6): 9604-9622, 2022 Mar 14.
Artículo en Inglés | MEDLINE | ID: mdl-35299384

RESUMEN

We present an iterative method to model the optical properties of a complete semitransparent perovskite solar cell. It is based on spectroscopic characterizations and accounts for porosity and incoherence effects. We provide the complex refractive indices of each layer, and we identify the main sources of optical losses. The optical model is also coupled to an electrical model of 4T perovskite/silicon tandem solar cells. It allows to evaluate the interplay between the optical and electrical losses, and the balance between the efficiency of the top and bottom cells. These models provide an effective way to design future tandem devices.

2.
J Neurosci ; 22(21): 9166-70, 2002 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-12417640

RESUMEN

In Alzheimer's disease (AD), the rhinal cortex is the area earliest and most affected by neurofibrillary tangles, and the degree of temporoparietal glucose hypometabolism and rhinal cortex atrophy are both correlated with dementia severity. In monkeys, damage to the rhinal cortex leads to severe impairment in declarative memory, which is also affected preferentially in early AD. To investigate the contribution of rhinal alterations to the interrelationships between cerebral hypometabolism and declarative memory impairment observed in AD, we studied the effects of excitotoxic bilateral rhinal lesions in baboons on cerebral glucose consumption (CMRglc) as measured by positron emission tomography and performance on a visual recognition memory task as assessed in parallel by a delayed nonmatching-to-sample task. We reported previously that these rhinal lesions induce both a long-lasting hypometabolism in several remote brain regions (Meguro et al., 1999) and impaired memory performance (Chavoix et al., 2002). The present analysis indicates that across lesioned and sham baboons, memory scores were significantly positively correlated (p < 0.05; Spearman) with concomitant CMRglc values of several brain areas, such as neocortical associative and posterior hippocampal regions. These findings, reminiscent of those reported in AD, suggest that the neurodegenerative process that affects the rhinal cortex in early AD plays a crucial role in the pattern of brain hypometabolism and consequently in the declarative memory impairments characteristic of this disease.


Asunto(s)
Enfermedad de Alzheimer/metabolismo , Glucosa/metabolismo , Hipocampo/metabolismo , Memoria/fisiología , Neocórtex/metabolismo , Reconocimiento Visual de Modelos/fisiología , Enfermedad de Alzheimer/inducido químicamente , Enfermedad de Alzheimer/patología , Animales , Conducta Animal/efectos de los fármacos , Modelos Animales de Enfermedad , Corteza Entorrinal/diagnóstico por imagen , Corteza Entorrinal/fisiología , Fluorodesoxiglucosa F18/farmacocinética , Hipocampo/diagnóstico por imagen , Masculino , Neocórtex/diagnóstico por imagen , Neurotoxinas , Papio , Giro Parahipocampal/diagnóstico por imagen , Giro Parahipocampal/fisiología , Estimulación Luminosa , Tomografía Computarizada de Emisión
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