RESUMEN
We report our experience on 42 patients treated with atrial septal defect (ASD) occlusion using Amplatzer device. Thirty patients were females and 12 were males, mean ages 26.5-years-old +/- 12 years (interval from 7 to 69 years). Average weight was 57.1 +/- 13.8 kg (32.3-85.0 kg). Forty-two devices (ranging diameters from 13 mm to 40 mm) were deployed, 40 of which were placed successfully and attempts were unsuccessful in two cases (diameter devices 36 mm and 40 mm, respectively). We used the "balloon on the left or right upper pulmonary vein" in 5 patients, achieving good deployment. Echocardiography showed total occlusion in 37 patients (93.5%), trivial leak in 2 (4.7%), and light leak in 1 patient (2.3%). Follow up was at 1 to 12 months (mean 6.5). Total occlusion was observed at one month on both patients with trivial leak, and at 6 months on the patient with light leak. Failure to deploy the device appropriately on the two patients with unsuccessful result was due to unfavorable anatomy: very large defects in both cases (occluder size 36 mm and 40 mm), very thin postero-superior 6 mm rim on one of them and aortic rim absence on the other one. Stretched diameters were 34 mm and 38 mm on patients with 36 mm and 40 mm devices, respectively. Both of them were sent to surgery. We conclude that percutaneus closure of atrial septal defect with the Amplatzer device is a save and have good results.
Asunto(s)
Defectos del Tabique Interatrial/cirugía , Prótesis e Implantes , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad , Implantación de Prótesis/métodos , Adulto JovenRESUMEN
The tricuspid atresia associated with persistent truncus arteriosus is a rare anomaly. A case is presented of one male patient of three months age in which was detected a cardiac murmur. The diagnosis was made by echocardiography and confirmed by cardiac catheterization. The first step of the palliation was done with disconnection of the trunk of the pulmonary artery combined with a systemic- to- pulmonary shunt of 4 mm. The patient died 24 hours later for persistent metabolic acidosis.
Asunto(s)
Atresia Tricúspide/cirugía , Tronco Arterial Persistente/cirugía , Cateterismo Cardíaco , Ecocardiografía , Resultado Fatal , Humanos , Lactante , Masculino , Atresia Tricúspide/diagnóstico , Tronco Arterial Persistente/diagnósticoRESUMEN
UNLABELLED: Behçet's disease uncommon in the pediatric population. Intracardiac thrombus and bilateral pulmonary artery aneurysms are uncommon manifestations. We are reporting one case. A 14 years old patient was admitted, with high fever, dyspnea and hemoptysis since 4 months ago. Two years ago, fever, oral ulcers, aphthae (gingival, palate, tonsils), nose ulceration in and arthralgias-arthritis were noted. Chest radiograph showed round mass in the right lower lung field. The chest tomographic computed scan and pulmonary centellography were done to investigate malformations arterial. An Intracardiac thrombus of 27 x 12 mm was identified in the right ventricle by transthoracic echocardiography. Catheterization and pulmonary angiography showed an aneurism located in the right and left lobares arteries. Medical management with immunosuppressive and anticoagulation therapy resulted in complete remission of the clinical manifestations. Due to heamodynamic compromise surgical removal of the intracardiac thrombus was done. IN SUMMARY: The Behçet's disease is rare disease in children. Intracardiac thrombus and bilateral pulmonary artery aneurysms are rare complications. Medical treatment (immunosupressive and anticoagulation) is the first line therapy with resolution of the mucous, skin, cardiac and pulmonary manifestations.
Asunto(s)
Aneurisma/etiología , Síndrome de Behçet/complicaciones , Cardiopatías/etiología , Ventrículos Cardíacos , Arteria Pulmonar , Trombosis/etiología , Adolescente , Aneurisma/diagnóstico , Cardiopatías/diagnóstico , Humanos , Masculino , Trombosis/diagnósticoRESUMEN
Endomyocardial biopsy (EB) is often used in the clinical evaluation of several cardiac disease. Hundred-seventy-six consecutive procedures were performed in 65 patients, 43 men and 22 women mean age was 29.86 +/- 11.53 (range 4 days to 66 years). Group A, 26 postcardiac transplantation patients in whom 137 EB were performed (39 heterotopic and 98 orthotopic), average sample 5.2 biopsy for each patient. Group B (n = 39) was studied for several cardiac diseases during cardiac diagnostic catheterism. The jugular venous approach was performed in 3 patients (1.7%), femoral in 173 patients. Major complications were found in 3 (1.7%) cases consisting in cerebrovascular accident (stroke) and coronary fistula into the right ventricle. Endomyocardial biopsy provides a low incidence of adverse reactions, mortality was 0%.
Asunto(s)
Miocardio/patología , Adolescente , Adulto , Anciano , Biopsia/efectos adversos , Biopsia/métodos , Niño , Preescolar , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Persona de Mediana EdadRESUMEN
In 2002, a group of Montagnard refugees living in Cambodia was accepted for resettlement in the United States. Pre-departure malaria screening and targeted treatment was conducted to prevent morbidity, and minimize the potential for local malaria transmission post-arrival. We screened 902 of 906 refugees using rapid diagnostic tests (RDTs), microscopy, and polymerase chain reaction (PCR) analysis. Twelve (1.3%) RDT results were positive and 28 (3.1%) were indeterminate. Microscopy confirmed Plasmodium species in two of the positive RDT and one of the indeterminate results. Among a random 10% sample of negative RDT results (n = 86), none were positive by microscopy. The PCR confirmed the two microscopically (and RDT) positive specimens. The PCR result was negative for all other specimens tested. Eighteen (2.0%) refugees were treated with antimalarials. The RDTs were useful in this setting, facilitating timely, sensitive diagnosis and targeted treatment. Evaluations to determine the most appropriate interventions in other refugee settings should include cost-effectiveness analyses of alternative strategies.
Asunto(s)
Malaria/diagnóstico , Malaria/tratamiento farmacológico , Refugiados , Antimaláricos/uso terapéutico , Cambodia/epidemiología , Humanos , Malaria/epidemiología , Reacción en Cadena de la PolimerasaRESUMEN
We report our experience with the percutaneous closure of patent ductus arteriosus with a Nit-Occlud device made of Nitinol (Nickel-Titanium alloy) in 13 patients; 10 women and 3 men, average age of 23.2 +/- 21.1 years. Average diameters were 3.8 +/- 0.8 mm and the morphologies, according to Krichenko's classification, were 10 type A, 2 type E, and 1 type C. The device was selected according to the aortic ampule and the narrowest part of the ductus. We implanted 8 occluders of 11 x 6 mm, 4 of 9 x 6 mm, and 1 of 7 x 6 mm. In three patients (25%) total occlusion was observed 15 minutes after implantation, in seven (54%) a trivial leak was observed, and in only two patients (16.6%) was the leak moderate to severe. In on patient, the occluder migrate to the pulmonary artery trunk and was successfully removed percutaneously; the patient was subjected then to surgical closure. Echocardiography follow-up 24 h later showed total occlusion in nine patients (69%). Six months after the procedure, two patient presented trivial leak (15%). One patient developed an endocarditic infection and died. We concluded that this occluder might be useful for this pathology, but further studies must be done.
Asunto(s)
Conducto Arterioso Permeable/cirugía , Prótesis e Implantes , Adolescente , Adulto , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Persona de Mediana Edad , Diseño de PrótesisRESUMEN
OBJECTIVE: We present two cases of Patent Foramen Ovale (PFO) treated with percutaneous Amplatzer device. METHOD: The first case corresponds to 48 years old woman with Ebstein's disease with moderate to severe hemodynamic repercussion and three cerebrovascular accidents, the last one under coumarin treatment, she received antiarrhythmic medication and despite of it developed 1st degree AV block, supraventricular and ventricular ectopia, rigth branch block. The second case corresponds to a 22 years old man with antecedents of cerebrovascular accident at the age of 21 with sequelae of convulsive crisis. Both patients were percutaneously treated with Amplatzer devices. The first patient was treated with a foramen ovale device and second with septal occluder due to the diameter of the foramen. Both patients have remained asymptomatic during the follow-up period. CONCLUSIONS: The PFO devices are indicated for patients with a history of cerebrovascular accidents.
Asunto(s)
Defectos del Tabique Interatrial/cirugía , Prótesis e Implantes , Implantación de Prótesis/métodos , Adulto , Anomalía de Ebstein/complicaciones , Femenino , Estudios de Seguimiento , Defectos del Tabique Interatrial/complicaciones , Defectos del Tabique Interatrial/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Accidente Cerebrovascular/prevención & control , Factores de Tiempo , Resultado del TratamientoRESUMEN
We performed transcatheter closure of an atrial septal defect (ASD) using an Amplatzer device in three patients, 2 women and 1 male child, aged 12, 54, and 4 years, respectively, coursing with ostium secundum ASD. Two with left to right shunt and the third with bidirectional shunt. The transesophageal echocardiogram revealed ASD with diameters of 13, 15, and 10 mm, the diameter with expanded catheter balloon was of 30, 26, and 17 mm, respectively. The superior border of the atrial septum was bigger than 5 mm in all three patients, whereas the inferior border could not be found through echocardiography in the patients aged 12 and 4 years. Amplatzer devices of 30, 26, and 17 mm were implanted, the inferior border of the first two could be supported on the aortic wall and the superior border on the septum. We observed a 100% occlusion in these two cases through ecocolor-Doppler. In the third patient, an inferior border of 16 mm and a superior border of 8 mm were determined, achieving and immediate and fast installation of the device with 100% occlusion. All three patients were in stable conditions, asymptomatic and without shunt at their one-month follow-up as revealed by a trans-thoracic echocardiography. It is concluded that the Amplatzer device is technically easy to install and yields adequate results even in patients with ample ASD and without inferior border of the inter-atrial septum.
Asunto(s)
Defectos del Tabique Interatrial/cirugía , Prótesis e Implantes , Niño , Preescolar , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
OBJECTIVES: To analyze immediate and long-term results of balloon dilation for aortic coarctation in a three-center experience in Mexico, and to determine factors associated with increased risk. BACKGROUND: Results demonstrated that the procedure is effective and safe, however its use in some groups is still controversial, specially in neonates and infants. METHODS: In a ten-year period, 333 patients with aortic coarctation on underwent balloon dilation with an immediate success rate of 93.7% and a major complication incidence of 1.8%. Of the total cohort, 272 patients were followed for a period of 24.3 +/- 20 months. Demographic and procedural data were analyzed to determine factors related to a poor outcome or to sustained high blood pressure. RESULTS: Cox regression analysis found age (risk ratio 3.42 p = 0.0001), isthmic hypoplasia (risk ratio 4.64, p < 0.0001), and post-dilation gradient (risk ratio 2.19, p = 0.0113) as independent risk factors for a follow-up event, mainly restenosis. Age at dilation was the only independent factor related to sustained hypertension with a seven-fold increase in the risk. CONCLUSIONS: Balloon dilation is an effective and safe alternative to treat aortic coarctation. Patients younger than one year of age, with severe isthmic hypoplasia and a post-dilation gradient > 20 mmHg have the highest risk to develop an event in the follow-up period. When the dilation procedure is performed in patients older than 10 years of age, and specially those older than 20 years, the probability that they remain or develop high blood pressure is increase.
Asunto(s)
Angioplastia de Balón , Coartación Aórtica/terapia , Adolescente , Adulto , Niño , Preescolar , Femenino , Estudios de Seguimiento , Humanos , Lactante , Recién Nacido , Masculino , México , Persona de Mediana EdadRESUMEN
Corn distiller's dried grains with solubles (DDGS) is a byproduct of the ethanol industry and has potential as a source of valuable compounds. In this study, corn DDGS was extracted using supercritical carbon dioxide (SC-CO(2)) at 50-70 °C, 34.5-49.6 MPa, and constant CO(2) flow rate of 1 L/min (measured at ambient conditions). The highest yield of total lipids (9.2%, w/w) was obtained at 49.6 MPa/70 °C. Apparent solubility of corn DDGS lipids ranged between 0.010 kg/kg CO(2) at 34.5 MPa/50 °C and 0.026 kg/kg CO(2) at 49.6 MPa/70 °C. The extract contained 107 mg/kg carotenoids, 1538 mg/kg tocochromanols, and 15904 mg/kg phytosterols at 49.6 MPa/70 °C. The Sovova model and Chrastil model were successfully used to describe the extraction of total lipids and apparent solubility of total and minor lipids, respectively. The study revealed that DDGS is a good inexpensive source of lipids and valuable minor lipid components and that SC-CO(2) extraction can be used as a "green" process to add value to corn DDGS by recovering such high-value lipids.
Asunto(s)
Cromatografía con Fluido Supercrítico , Semillas/química , Zea mays/química , Dióxido de Carbono , Carotenoides/análisis , Cromanos/análisis , Lípidos/análisis , Lípidos/química , Modelos Teóricos , Fitosteroles/análisis , Extractos Vegetales/química , SolubilidadRESUMEN
BACKGROUND: Because of the strong association between abdominal obesity (AO) and other cardiovascular risk factors, it has been difficult to determine which changes in vascular function are directly related to this condition. Our objective was to evaluate the changes in ex-vivo vascular reactivity, circulating levels of adipokines and inflammatory markers associated with the presence of AO in subjects who underwent coronary artery bypass graft (CABG) controlling by the presence of other cardiovascular risk factors. METHODS: Subjects scheduled for a CABG with (n=17) and without (n=17) AO (defined as a waist circumference > or =90 cm for male or > or =80 cm for female) whom were matched by several cardiovascular risk factors, were included in the study. Lipid profile and plasma levels of glucose, insulin, leptin, adiponectin and inflammatory markers were measured. Internal mammary artery segments were used for ex-vivo vascular reactivity experiments and morphometry. RESULTS: Leptin concentrations were higher and adiponectin concentrations were lower in subjects with AO. No differences were observed in other biochemical or clinical parameters between the groups. No correlation between waist circumference, HOMA index and inflammatory markers were observed. Endothelium-dependent relaxation to acetylcholine was lower, and contractile responses to angiotensin-II were higher in subjects with AO. These changes were not related to differences in vascular morphometry. CONCLUSION: In subjects with severe coronary disease, the presence of AO was associated with leptin/adiponectin imbalance, decreased endothelium-dependent relaxation and an enhanced response to angiotensin-II. These changes occurred independently of other cardiovascular risk factors including insulin resistance and levels of inflammatory markers.
Asunto(s)
Enfermedad de la Arteria Coronaria/epidemiología , Enfermedad de la Arteria Coronaria/metabolismo , Obesidad Abdominal/epidemiología , Obesidad Abdominal/metabolismo , Adiponectina/sangre , Biomarcadores/sangre , Glucemia , Puente de Arteria Coronaria/estadística & datos numéricos , Enfermedad de la Arteria Coronaria/cirugía , Femenino , Humanos , Insulina/sangre , Resistencia a la Insulina , Leptina/sangre , Lípidos/sangre , Masculino , Arterias Mamarias/trasplante , Persona de Mediana Edad , Análisis Multivariante , Factores de Riesgo , Índice de Severidad de la Enfermedad , Vasoconstricción/fisiologíaRESUMEN
Las recomendaciones para la biopsia por aspiración con aguja fina de mama se desarrollaron y aprobaron en 1997 por el Instituto Nacional de Cáncer en Bethesda, Estados Unidos y fueron adaptadas a nuestro país en 2007, sin embargo, en los últimos años no se han realizado cambios formales en estas indicaciones. El objetivo de este módulo es presentar la actualización del reporte de biopsia por aspiración con aguja fina de mama, usando el sistema de reporte Bethesda, realizado por consenso con un grupo de patólogos, clínicos, radiólogos, cirujanos de mama y otros profesionales de la salud de Colombia y otros países, y con base en la experiencia realizando biopsia por aspiración con aguja fina de mama del Hospital Pablo Tobón Uribe y de Dinámica IPS.
Recommendations for breast fine needle aspiration biopsy were developed and approved in 1997 by The National Cancer Institute of Bethesda, United States, , and were adapted to our country on 2007, however, in last years these indications have not changed in a formal manner. The purpose of this review was to provide an update of the report for breast fine needle aspiration biopsy using the Bethesda system. This guide was made by consensus with pathologists, clinicians, radiologists, breast surgeons and other health professionals of Colombia and other countries. The update was basis on the experience of Hospital Pablo Tobon Uribe and Dinamica IPS in performing breast fine needle aspiration biopsy.
Asunto(s)
Humanos , Biopsia con Aguja Fina , Enfermedades de la MamaRESUMEN
El defecto del septo atrial es la segunda patología congénita del corazón más común en adultos, con predominancia en el sexo femenino. Adicionalmente, el 70% corresponde a la variedad ostium secundum. Cuando este tipo de defecto se diagnostica en la niñez pero no se recibe tratamiento, se provoca un aumento del diámetro, de donde sólo el 4% de los casos se cierra de manera espontánea. Por lo general, un paciente con un defecto del septo atrial de la variedad ostium secundum, permanece asintomático hasta la tercera o cuarta décadas de la vida, etapas en las que comienza a disminuir su capacidad para hacer ejercicio, desarrolla fatiga, puede presentar síncope y palpitaciones, o falla ventricular derecha, taquicardia atrial, hipertensión pulmonar y eventos embólicos. Todos estos elementos contribuyen a una morbilidad significativa que, por tanto, puede conducir a la muerte. Entre tanto, la edad de inicio de los síntomas es variable y no se correlaciona con el tamaño del defecto ni con el grado del cortocircuito; sin embargo, Rosas y colaboradores, en un seguimiento a 200 pacientes mayores a 40 años no tratados, observaron cinco muertes súbitas, siete fallas cardiacas, trece infecciones pulmonares severas, cinco embolismos y cuatro accidentes cerebrovasculares (1). De otro lado, se sabe que el reparo de los defectos del septo atrial puede prevenir la hipertensión pulmonar, la falla del ventrículo derecho y las complicaciones tromboembólicas.
Asunto(s)
Equipos y Suministros , Cirugía General , Tabique Interatrial , CardiopatíasRESUMEN
We evaluated the effectiveness of an overseas pre-departure regimen of five days of albendazole for presumptive treatment of intestinal parasites by examining stool specimens in treated and untreated Montagnard refugees after arrival in the United States. Among 815 refugees evaluated, fully treated refugees had a significantly lower prevalence of helminths (11 [1.4%] of 777), specifically hookworm and Ascaris lumbricoides, than untreated pregnant women (3 [20%] of 15) (P < 0.001). Multivariate analysis showed that treatment was associated with significantly lower rates of infection with helminths but not protozoa. Post-arrival gastrointestinal symptoms were not associated with findings on stool examination. Our evaluation suggests that although additional studies are needed to determine optimal treatment regimens for intestinal parasites, especially among young children and pregnant women, a five-day course of pre-departure albendazole was effective in reducing helminthic infection in treated refugees.
Asunto(s)
Albendazol/uso terapéutico , Antihelmínticos/uso terapéutico , Helmintiasis/prevención & control , Refugiados , Animales , Cambodia/etnología , Centers for Disease Control and Prevention, U.S. , Helmintiasis/transmisión , Humanos , Inmunoglobulina G/sangre , Análisis Multivariante , North Carolina , Viaje , Trypanosoma brucei gambiense , Tripanosomiasis Africana/diagnóstico , Tripanosomiasis Africana/tratamiento farmacológico , Moscas Tse-Tse , Estados UnidosRESUMEN
We report our experience on 42 patients treated with atrial septal defect (ASD) occlusion using Amplatzer device. Thirty patients were females and 12 were males, mean ages 26.5-years-old +/- 12 years (interval from 7 to 69 years). Average weight was 57.1 +/- 13.8 kg (32.3-85.0 kg). Forty-two devices (ranging diameters from 13 mm to 40 mm) were deployed, 40 of which were placed successfully and attempts were unsuccessful in two cases (diameter devices 36 mm and 40 mm, respectively). We used the [quot ]balloon on the left or right upper pulmonary vein[quot ] in 5 patients, achieving good deployment. Echocardiography showed total occlusion in 37 patients (93.5%), trivial leak in 2 (4.7%), and light leak in 1 patient (2.3%). Follow up was at 1 to 12 months (mean 6.5). Total occlusion was observed at one month on both patients with trivial leak, and at 6 months on the patient with light leak. Failure to deploy the device appropriately on the two patients with unsuccessful result was due to unfavorable anatomy: very large defects in both cases (occluder size 36 mm and 40 mm), very thin postero-superior 6 mm rim on one of them and aortic rim absence on the other one. Stretched diameters were 34 mm and 38 mm on patients with 36 mm and 40 mm devices, respectively. Both of them were sent to surgery. We conclude that percutaneus closure of atrial septal defect with the Amplatzer device is a save and have good results.
Asunto(s)
Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven , Defectos del Tabique Interatrial , Prótesis e Implantes , Implantación de Prótesis/métodosRESUMEN
Justificación: existe un grupo de pacientes con angina de pecho crónica refractaria, que no son candidatos a revascularización quirúrgica o percutánea y que a pesar de recibir un manejo médico óptimo, aún experimentan severos episodios de angina. El estimulador eléctrico espinal es un neuromodulador que se emplea como alternativa de manejo en estos pacientes. Objetivos: se realizó una revisión sobre estimulación eléctrica espinal en el manejo de la angina, su mecanismo de acción, sus beneficios y su costo-efectividad. Materiales y métodos: se llevó a cabo una búsqueda en MedLine, según la metodología Cochrane, de artículos publicados desde enero de 1980 a enero de 2007, mediante los términos ®spinal cord stimulation¼; de ésta se seleccionaron los manuscritos que los autores consideraron relevantes. Conclusiones: el efecto anti-isquémico del estimulador espinal eléctrico reduce los episodios de angina de pecho, mejora la calidad de vida y la tolerancia al ejercicio, disminuye la estancia hospitalaria y retarda la aparición de signos de isquemia.
Asunto(s)
Angina de Pecho , Análisis Costo-Beneficio , Estimulación EléctricaRESUMEN
The tricuspid atresia associated with persistent truncus arteriosus is a rare anomaly. A case is presented of one male patient of three months age in which was detected a cardiac murmur. The diagnosis was made by echocardiography and confirmed by cardiac catheterization. The first step of the palliation was done with disconnection of the trunk of the pulmonary artery combined with a systemic- to- pulmonary shunt of 4 mm. The patient died 24 hours later for persistent metabolic acidosis.
Asunto(s)
Humanos , Lactante , Masculino , Atresia Tricúspide , Tronco Arterial Persistente , Cateterismo Cardíaco , Ecocardiografía , Resultado Fatal , Atresia Tricúspide , Tronco Arterial PersistenteRESUMEN
Desde hace más de treinta años, la inserción quirúrgica de puentes aorto-coronarios autólogos de vena safena y de arteria mamaria, constituye el tratamiento de elección para pacientes con enfermedad coronaria severa. La vida útil de estos injertos ha demostrado ser mayor en los colgajos de tipo arterial, aunque su uso está limitado por la restringida disponibilidad de los mismos. Por esta razón, y a pesar de que tienen mayor riesgo de presentar oclusión, los injertos de vena safena son los que más se usan en estos procedimientos de reperfusión miocárdica. Aún no se han esclarecido del todo las razones por las cuales los injertos venosos se ocluyen luego de su inserción en los lechos arteriales; no obstante, se ha propuesto que podría deberse a diferentes factores como: trauma mecánico quirúrgico, aumento de la presión arterial y disminuido estrés de fricción.En 1996 se describió la técnica no-touch de preparación de los injertos venosos, en la cual se implantaron los puentes venosos en los lechos coronarios junto con el tejido peri-vascular que los circunda, y demostró mejorar la vida útil de este tipo de injertos. Recientemente se ha propuesto que el tejido adiposo peri-vascular podría desempeñar un papel en la regulación del tono vascular, e incluso se ha descrito la existencia de un factor relajante derivado del adipocito (ADRF), cuya naturaleza no se ha esclarecido completamente.El objetivo de este articulo es revisar los diferentes factores vinculados con la oclusión de los injertos aorto-coronarios, las posibles vías fisiopatológicas que configuran este fenómeno, las nuevas alternativas quirúrgicas utilizadas para la preparación de los injertos venosos y los avances en la descripción del ADRF y su papel en la regulación del tono vascular.
Since more than thirty years, surgical insertion of autologous aortocoronary bypasses from saphenous vein and mammary artery constitute the election treatment for patients with severe coronary disease. The lifespan of these grafts has shown to be longer with arterial tissue even though its use is limited by its restricted availability. This is why the saphenous vein bypasses, although having a greater risk of presenting occlusion, are the most used in these procedures of myocardial reperfusion. The reasons by which the venous grafts are occluded after its insertion in the arterial site are still not clear; nevertheless, it has been proposed that it could be due to different factors such as: surgical mechanical trauma, increment of arterial pressure and diminished friction stress. In 1996 the «no-touch¼ preparation technique of venous grafts was described, in which the venous bypasses were implanted in the coronary site along with the surrounding perivascular tissue and demonstrated to improve the lifespan of this type of grafts. Recently it has been proposed that the perivascular fat tissue could play a role in the vascular tone regulation and it has been even described the existence of an adipose cell derived relaxing factor (ADRF), whose nature has not been completely cleared yet. The objective of this article is to review the different factors related to the aortocoronary grafts occlusion, the possible physiopathologic channels that form this phenomenon, the new surgical alternatives used for vein grafts preparation and the advances in the description of ADRF and its role in vascular tone regulation.
Asunto(s)
Tejido Adiposo , Presión Sanguínea , Puente de Arteria Coronaria , Enfermedad Coronaria , Revascularización Miocárdica , Vena Safena , TrasplantesRESUMEN
Behçet's disease uncommon in the pediatric population. Intracardiac thrombus and bilateral pulmonary artery aneurysms are uncommon manifestations. We are reporting one case. A 14 years old patient was admitted, with high fever, dyspnea and hemoptysis since 4 months ago. Two years ago, fever, oral ulcers, aphthae (gingival, palate, tonsils), nose ulceration in and arthralgias-arthritis were noted. Chest radiograph showed round mass in the right lower lung field. The chest tomographic computed scan and pulmonary centellography were done to investigate malformations arterial. An Intracardiac thrombus of 27 x 12 mm was identified in the right ventricle by transthoracic echocardiography. Catheterization and pulmonary angiography showed an aneurism located in the right and left lobares arteries. Medical management with immunosuppressive and anticoagulation therapy resulted in complete remission of the clinical manifestations. Due to heamodynamic compromise surgical removal of the intracardiac thrombus was done. IN SUMMARY: The Behçet's disease is rare disease in children. Intracardiac thrombus and bilateral pulmonary artery aneurysms are rare complications. Medical treatment (immunosupressive and anticoagulation) is the first line therapy with resolution of the mucous, skin, cardiac and pulmonary manifestations.
Asunto(s)
Adolescente , Humanos , Masculino , Aneurisma , Síndrome de Behçet , Ventrículos Cardíacos , Cardiopatías , Arteria Pulmonar , Trombosis , Aneurisma , Cardiopatías , TrombosisRESUMEN
Antecedentes: desde 1991 la técnica endovascular se ha aplicado con éxito en el manejo de los aneurismas de aorta infrarrenal, y se ha perfeccionado de manera tal que rápidamente se ha convertido en una alternativa para pacientes de alto riesgo para la cirugía convencional. Objetivo: describir los resultados institucionales en el manejo de las patologías de aorta abdominal e ilíacas mediante técnica endovascular desde 2003 a 2005.Diseño-Método: estudio descriptivo, longitudinal, retrospectivo, en el que se analizaron las historias clínicas de los pacientes sometidos a procedimiento endovascular de aorta abdominal e ilíacas. El análisis se realizó en Stata 8,0 S/E...
Antecedents: since 1991 endovascular technique has been successfully used in the management of infra-renal aortic aneurysms and it has been improved in such a way that it has quickly turned into an alternative for patients considered having high risk for conventional surgery. Objective: describe the institutional results in the management of abdominal aortic pathologies through endovascular technique from 2003 to 2005. Design-Method: descriptive, longitudinal, retrospective study in which clinical histories of patients that underwent an endovascular procedure of abdominal aorta and iliac arteries were analyzed. The analysis was performed in Stata 8,0 S/E. Results: 9 patients received exclusively treatment for abdominal aortic and iliac lesions. All were male individuals with mean age 68.9 ± 8.1 years. 6 patients had diagnosis of infra-renal aortic aneurysm and the other 3 had anastomotic aneurysms. Requirement of endoprosthesis was evidenced in an average of 1.9 ± 0.8. Femoro-femoral bypass surgery was performed as simultaneous procedure in 4 of the 9 patients. 77.8% of patients had no complications. Mortality due to the procedure was 22% (2 patients) and it is important to notice that only these 2 patients had complications. Conclusions: exclusion of aortic and iliac aneurysms with modular endoprosthesis is being widely implemented as a valid treatment option, with excellent results that avoid the risks of conventional surgery and its associated morbidity.