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1.

A gut-derived hormone regulates cholesterol metabolism.

Hu, Xiaoli; Chen, Fengyi; Jia, Liangjie; Long, Aijun; Peng, Ying; Li, Xu; Huang, Junfeng; Wei, Xueyun; Fang, Xinlei; Gao, Zihua; Zhang, Mengxian; Liu, Xiao; Chen, Ye-Guang; Wang, Yan; Zhang, Huijie; Wang, Yiguo.

Cell ; 187(7): 1685-1700.e18, 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38503280

2.

PPM1A Functions as a Smad Phosphatase to Terminate TGFß Signaling.

Lin, Xia; Duan, Xueyan; Liang, Yao-Yun; Su, Ying; Wrighton, Katharine H; Long, Jianyin; Hu, Min; Davis, Candi M; Wang, Jinrong; Brunicardi, F Charles; Shi, Yigong; Chen, Ye-Guang; Meng, Anming; Feng, Xin-Hua.

Cell ; 165(2): 498, 2016 Apr 07.

Artículo en Inglés | MEDLINE | ID: mdl-27058669

3.

PPM1A Functions as a Smad Phosphatase to Terminate TGFß Signaling.

Lin, Xia; Duan, Xueyan; Liang, Yao-Yun; Su, Ying; Wrighton, Katharine H; Long, Jianyin; Hu, Min; Davis, Candi M; Wang, Jinrong; Brunicardi, F Charles; Shi, Yigong; Chen, Ye-Guang; Meng, Anming; Feng, Xin-Hua.

Cell ; 166(6): 1597, 2016 Sep 08.

Artículo en Inglés | MEDLINE | ID: mdl-27610577

4.

Regulation of Dishevelled protein activity and stability by post-translational modifications and autophagy.

Shi, Qiaoni; Chen, Ye-Guang.

Trends Biochem Sci ; 46(12): 1003-1016, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34433516

5.

Upregulation of CYR61 by TGF-ß and YAP signaling exerts a counter-suppression of hepatocellular carcinoma.

Zhang, Cheng; Wei, Wenjing; Tu, Shuo; Liang, Bo; Li, Chun; Li, Yining; Luo, Weicheng; Wu, Yiqing; Dai, Xiaohui; Wang, Yi; Zheng, Lijuan; Hao, Liang; Zhang, Chunbo; Luo, Zhijun; Chen, Ye-Guang; Yan, Xiaohua.

J Biol Chem ; 300(4): 107208, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38521502

6.

Noncanonical TGF-ß signaling leads to FBXO3-mediated degradation of ΔNp63α promoting breast cancer metastasis and poor clinical prognosis.

Niu, Mengmeng; He, Yajun; Xu, Jing; Ding, Liangping; He, Tao; Yi, Yong; Fu, Mengyuan; Guo, Rongtian; Li, Fengtian; Chen, Hu; Chen, Ye-Guang; Xiao, Zhi-Xiong Jim.

PLoS Biol ; 19(2): e3001113, 2021 02.

Artículo en Inglés | MEDLINE | ID: mdl-33626035

7.

Finale: the last minutes of Smads.

Chen, Ye-Guang; Wang, Xiao-Fan.

Cell ; 139(4): 658-60, 2009 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-19914161

8.

A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche.

Xiang, Jinnan; Guo, Jigang; Zhang, Shaoyang; Wu, Hongguang; Chen, Ye-Guang; Wang, Junping; Li, Baojie; Liu, Huijuan.

BMC Biol ; 21(1): 169, 2023 08 08.

Artículo en Inglés | MEDLINE | ID: mdl-37553612

9.

Liquid-liquid phase separation drives the ß-catenin destruction complex formation.

Shi, Qiaoni; Kang, Kexin; Chen, Ye-Guang.

Bioessays ; 43(10): e2100138, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34418117

10.

Crafting figures to describe cellular processes.

Kmiecik, Szymon W; Shi, Qiaoni; Chen, Ye-Guang; Moormann, Jannis; Hildebrandt, Tatjana M; Schade, Amy; Fischer, Martin; Kim, Kyusik Q.

Trends Biochem Sci ; 48(6): 491-494, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-37172571

11.

DDB1 promotes the proliferation and hypertrophy of chondrocytes during mouse skeleton development.

Zhao, Lianzheng; Wang, Xiaodan; Pomlok, Kumpanat; Liao, Hongwei; Yang, Guan; Yang, Xiao; Chen, Ye-Guang.

Dev Biol ; 465(2): 100-107, 2020 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-32479761

12.

LGR5 constitutively activates NF-κB signaling to regulate the growth of intestinal crypts.

Lai, Shanshan; Cheng, Ran; Gao, Dan; Chen, Ye-Guang; Deng, Cheng.

FASEB J ; 34(11): 15605-15620, 2020 11.

Artículo en Inglés | MEDLINE | ID: mdl-33001511

13.

c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-ß type II receptor.

Zuo, Wei; Huang, Fei; Chiang, Y Jeffrey; Li, Meng; Du, Jun; Ding, Yi; Zhang, Ting; Lee, Hyuk Woo; Jeong, Lak Shin; Chen, Yuling; Deng, Haiteng; Feng, Xin-Hua; Luo, Shiwen; Gao, Chunji; Chen, Ye-Guang.

Mol Cell ; 49(3): 499-510, 2013 Feb 07.

Artículo en Inglés | MEDLINE | ID: mdl-23290524

14.

Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.

Ye, Pan; Chiang, Y Jeffrey; Qi, Zhen; Li, Yehua; Wang, Shan; Liu, Yuan; Li, Xintong; Chen, Ye-Guang.

PLoS Genet ; 14(9): e1007697, 2018 09.

Artículo en Inglés | MEDLINE | ID: mdl-30260955

15.

Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-ß signaling.

Yu, Yi; Gu, Shuchen; Li, Wenjian; Sun, Chuang; Chen, Fenfang; Xiao, Mu; Wang, Lei; Xu, Dewei; Li, Ye; Ding, Chen; Xia, Zongping; Li, Yi; Ye, Sheng; Xu, Pinglong; Zhao, Bin; Qin, Jun; Chen, Ye-Guang; Lin, Xia; Feng, Xin-Hua.

Proc Natl Acad Sci U S A ; 114(38): 10113-10118, 2017 09 19.

Artículo en Inglés | MEDLINE | ID: mdl-28874583

16.

Activin/Smad2 and Wnt/ß-catenin up-regulate HAS2 and ALDH3A2 to facilitate mesendoderm differentiation of human embryonic stem cells.

Xu, Xuanhao; Wang, Lu; Liu, Bofeng; Xie, Wei; Chen, Ye-Guang.

J Biol Chem ; 293(48): 18444-18453, 2018 11 30.

Artículo en Inglés | MEDLINE | ID: mdl-30282636

17.

AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.

Lin, Hui; Ying, Ying; Wang, Yuan-Yuan; Wang, Gang; Jiang, Shan-Shan; Huang, Deqinag; Luo, Lingyu; Chen, Ye-Guang; Gerstenfeld, Louis C; Luo, Zhijun.

Biochim Biophys Acta Mol Cell Res ; 1864(12): 2369-2377, 2017 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-28847510

18.

Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells.

Wang, Lu; Xu, Xuanhao; Cao, Yaqiang; Li, Zhongwei; Cheng, Hao; Zhu, Gaoyang; Duan, Fuyu; Na, Jie; Han, Jing-Dong J; Chen, Ye-Guang.

J Biol Chem ; 292(4): 1339-1350, 2017 01 27.

Artículo en Inglés | MEDLINE | ID: mdl-27965357

19.

Feedback regulation of TGF-ß signaling.

Yan, Xiaohua; Xiong, Xiangyang; Chen, Ye-Guang.

Acta Biochim Biophys Sin (Shanghai) ; 50(1): 37-50, 2018 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-29228156

20.

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-ß (TGF-ß)/Smad Signaling.

Yan, Xiaohua; Liao, Hongwei; Cheng, Minzhang; Shi, Xiaojing; Lin, Xia; Feng, Xin-Hua; Chen, Ye-Guang.

J Biol Chem ; 291(1): 382-92, 2016 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-26555259

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A gut-derived hormone regulates cholesterol metabolism.

PPM1A Functions as a Smad Phosphatase to Terminate TGFß Signaling.

PPM1A Functions as a Smad Phosphatase to Terminate TGFß Signaling.

Regulation of Dishevelled protein activity and stability by post-translational modifications and autophagy.

Upregulation of CYR61 by TGF-ß and YAP signaling exerts a counter-suppression of hepatocellular carcinoma.

Noncanonical TGF-ß signaling leads to FBXO3-mediated degradation of ΔNp63α promoting breast cancer metastasis and poor clinical prognosis.

Finale: the last minutes of Smads.

A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche.

Liquid-liquid phase separation drives the ß-catenin destruction complex formation.

Crafting figures to describe cellular processes.

DDB1 promotes the proliferation and hypertrophy of chondrocytes during mouse skeleton development.

LGR5 constitutively activates NF-κB signaling to regulate the growth of intestinal crypts.

c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-ß type II receptor.

Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.

Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-ß signaling.

Activin/Smad2 and Wnt/ß-catenin up-regulate HAS2 and ALDH3A2 to facilitate mesendoderm differentiation of human embryonic stem cells.

AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.

Activin/Smad2-induced Histone H3 Lys-27 Trimethylation (H3K27me3) Reduction Is Crucial to Initiate Mesendoderm Differentiation of Human Embryonic Stem Cells.

Feedback regulation of TGF-ß signaling.

Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-ß (TGF-ß)/Smad Signaling.