RESUMEN
An "off-the-shelf" cell therapy derived from induced pluripotent stem cells (iPSCs) has entered clinical trials in the United States. Other companies are following suit, harnessing iPSCs' self-renewal ability to manufacture cell therapies that don't require customization for each patient. But some experts aren't sure such therapies are a good idea.
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Diferenciación Celular , Tratamiento Basado en Trasplante de Células y Tejidos , Células Madre Pluripotentes Inducidas/metabolismo , Humanos , Células Madre Pluripotentes Inducidas/patologíaRESUMEN
Millions of people have taken direct-to-consumer DNA tests, but not everyone is happy with the status quo. Several startups in the genetic testing space are aiming to empower individuals and build communities in order to boost research and, ultimately, public health.
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Pruebas Dirigidas al Consumidor/ética , Pruebas Dirigidas al Consumidor/tendencias , Pruebas Genéticas/ética , Pruebas Genéticas/tendencias , Genómica/métodos , HumanosRESUMEN
Should we get our microbiomes sequenced? Do we shape our microbes, or do our microbes shape us? These are just a few of the questions at the border between microbiome science and humanities.
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Microbioma Gastrointestinal/fisiología , Interacciones Microbiota-Huesped , Intestinos/microbiología , Investigación/tendencias , Microbioma Gastrointestinal/genética , Secuenciación de Nucleótidos de Alto Rendimiento , HumanosRESUMEN
The Chan Zuckerberg Initiative, the philanthropy launched by Facebook CEO Mark Zuckerberg and his wife Priscilla Chan, drew attention with its stated goal of helping to "cure, manage, or treat all diseases" by the end of the century. They intend to do it through funding basic research and addressing gaps in biomedical technology.
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Investigación Biomédica/economía , Apoyo a la Investigación como Asunto , Terapéutica/economía , Investigación Biomédica/organización & administración , Organización de la Financiación/organización & administración , Obtención de Fondos , San FranciscoRESUMEN
To study how genes, cells, or organisms operate in natural environments, researchers often need to leave the bench and venture into the field. Here are a few approaches that field biologists use in designing and conducting semi-wild experiments and the many challenges they face.