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Rev Argent Microbiol ; 41(3): 185-96, 2009.
Artículo en Español | MEDLINE | ID: mdl-19831318

RESUMEN

The genus Cryptosporidium, responsible for producing cryptosporidiosis, includes several species. Humans and livestock are the main sources of infection. Waterborne cryptosporidiosis outbreaks are associated with drinking water. The infective parasite stage is the oocyst, which is resistant to conventional potabilization treatments. In immunocompetent hosts it produces acute, self-limiting diarrhoea. In immunocompromised people, it could develop severe, life-threatening pattern forms of the infection. People with AIDS are especially susceptible to these clinical forms. Cryptosporidium infections are also considered a major cause of morbimortality in calves, which leads to important economic losses. In the last years, there has been an increase of patients suffering from different causes of immunosuppression, and the need to find an effective therapy against Cryptosporidium has become greater. In spite of the many attempts of the pharmaceutical industry to develop an effective antiparasitic agent to treat cryptosporidiosis, this infection and its clinical consequences still constitute a major public health problem. This article analizes the taxonomy, morphology, biology and life cycle of Cryptosporidium. Clinical, immunological, epidemiological features and diagnosis of cryptosporidiosis are also included. Treatment and prevention of the infection are discussed, and future tendencies are suggested for this emerging parasitic infection.


Asunto(s)
Enfermedades Transmisibles Emergentes/epidemiología , Criptosporidiosis/epidemiología , Cryptosporidium/fisiología , Infecciones Oportunistas Relacionadas con el SIDA/epidemiología , Infecciones Oportunistas Relacionadas con el SIDA/parasitología , Animales , Animales Domésticos/parasitología , Animales Salvajes/parasitología , Anticuerpos Antiprotozoarios/sangre , Enfermedades Transmisibles Emergentes/economía , Enfermedades Transmisibles Emergentes/parasitología , Enfermedades Transmisibles Emergentes/fisiopatología , Criptosporidiosis/economía , Criptosporidiosis/fisiopatología , Criptosporidiosis/prevención & control , Criptosporidiosis/veterinaria , Cryptosporidium/inmunología , Cryptosporidium/aislamiento & purificación , Diarrea/epidemiología , Diarrea/parasitología , Peces/parasitología , Contaminación de Alimentos , Parasitología de Alimentos , Humanos , Inmunidad Innata , Huésped Inmunocomprometido , Estadios del Ciclo de Vida , Verduras/parasitología , Microbiología del Agua , Zoonosis
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