RESUMEN
BACKGROUND: Breast cancer is the most common cancer in women worldwide. Approximately 70% of female breast cancer patients have a body mass index (BMI) >25. In obesity, adipose tissue secretes additional resistin, which prompts a proinflammatory effect through its action on adenylate cyclase-associated protein 1 (CAP1). Several studies have associated the RETN gene single nucleotide polymorphism (SNP) rs1862513 (-420CAsunto(s)
Biomarcadores de Tumor/genética
, Neoplasias de la Mama/sangre
, Neoplasias de la Mama/genética
, Proteínas de Ciclo Celular/genética
, Proteínas del Citoesqueleto/genética
, Polimorfismo de Nucleótido Simple
, Resistina/genética
, Adulto
, Alelos
, Índice de Masa Corporal
, Neoplasias de la Mama/etnología
, Neoplasias de la Mama/patología
, Estudios de Casos y Controles
, Femenino
, Expresión Génica
, Tamización de Portadores Genéticos
, Humanos
, México
, Persona de Mediana Edad
, Obesidad/etnología
, Obesidad/genética
, Posmenopausia
, Premenopausia
, Resistina/sangre