RESUMEN
BACKGROUND: Segmental vitiligo (SV), which frequently accompanies poliosis, indicating a poor prognosis that is likely resistant to treatments. OBJECTIVES: In this study, we performed a retrospective analysis to evaluate the treatment response to 308 nm excimer laser in SV patients. METHODS: A retrospective chart and photographic review was performed on 80 SV patients who had been treated with 308nm excimer laser for >3 months. RESULTS: Eighty patients with SV (mean age: 24.0 years ± 15.3, males: 50%) were included in this study. The mean grade of repigmentation was 2.3 after 20.6 months of mean treatment duration; 23.8% of 80 patients showed grade 4, 20% showed grade 3, and 56.2% showed grade 1-2 repigmentation. However, none of them achieved complete repigmentation with excimer laser. The degree of repigmentation was positively correlated with treatment duration (r=0.315, P=0.004) and cumulative ultraviolet (UV) dosage (r=0.366, P=0.001), whereas it was negatively correlated with disease duration (r=-0.265, P=0.017). CONCLUSION: This study suggests that SV has a better repigmentation response when excimer laser is used at earlier stages of the disease and long-term use and high cumulative UV energy of the excimer laser elicit better responses. Additional treatments like surgical procedures in addition to excimer laser should be considered for complete repigmentation.
Asunto(s)
Terapia por Láser , Terapia Ultravioleta , Vitíligo/terapia , Adolescente , Adulto , Niño , Preescolar , Relación Dosis-Respuesta en la Radiación , Femenino , Humanos , Rayos Láser , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Pigmentación de la Piel/efectos de la radiación , Rayos Ultravioleta , Vitíligo/patologíaAsunto(s)
Dihidroxicolecalciferoles/uso terapéutico , Láseres de Excímeros/uso terapéutico , Terapia por Luz de Baja Intensidad/métodos , Vitíligo/patología , Vitíligo/terapia , Administración Tópica , Adolescente , Adulto , Antiinflamatorios/uso terapéutico , Terapia Combinada , Estética , Femenino , Humanos , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Estudios Prospectivos , Medición de Riesgo , Método Simple Ciego , Resultado del Tratamiento , Adulto JovenAsunto(s)
Ácido Aminolevulínico/administración & dosificación , Terapia por Láser , Fotoquimioterapia , Fármacos Fotosensibilizantes/administración & dosificación , Enfermedades de las Glándulas Sebáceas/tratamiento farmacológico , Enfermedades de las Glándulas Sebáceas/radioterapia , Administración Tópica , Adolescente , Adulto , Ácido Aminolevulínico/uso terapéutico , Dióxido de Carbono , Niño , Preescolar , Femenino , Humanos , Hiperplasia , Masculino , Persona de Mediana Edad , Fármacos Fotosensibilizantes/uso terapéutico , Enfermedades de las Glándulas Sebáceas/patologíaRESUMEN
A 53-year-old male presented with a 6-year duration of a child's-palm sized hypopigmented patch located on his neck. He had a history of surgical excision of an epidermal cyst on the neck, and the hypopigmented patch developed about one month after the excision next to the surgery site. Application of cold or heat did not make the lesion distinct from the surrounding skin. Pressure on the lesion by a glass slide made the lesion indistinguishable from surrounding uninvolved lesions. Giving friction to the lesion failed to induce erythematous change, making it clearly visible. Histologically, the lesion showed normal findings with adequate numbers of melanocytes in the basal layer. Herein, we present an interesting case of an acquired anemic patch which developed after a cyst excision. We postulate that nerve damage after surgery that regulates the vascular tone of cutaneous vessels may have been an inducing event of the anemic patch in this patient.
RESUMEN
Schwannoma is a benign neoplasm of the nerve sheath origin. It arises from the nerve sheath of large peripheral or cranial nerves and occurs at the level of the subcutaneous fat layer or deeper layer. Cutaneous schwannoma occurs more superficially and usually presents as a solitary dermal or subcutaneous nodule. We describe a case of cutaneous schwannoma that presented as an erythematous pedunculated protruding mass on the left flank of a 19-year-old female. It was clinically diagnosed as a granuloma pyogenicum. Shaving biopsy was conducted and histological examination revealed an encapsulated tumor mass containing dense, spindle-shaped cells whose nuclei are arranged back to back representing Verocay body, and a diagnosis of schwannoma was made. This is an unusual case of cutaneous schwannoma that presented as a pedunculated protruding mass.
RESUMEN
BACKGROUND: Acne vulgaris is a distressing condition that affects the majority of adolescents, but the impact of acne vulgaris on the psychological aspects in this age group is poorly understood. OBJECTIVE: The purpose of this study was to determine the prevalence of acne, and the level of emotional, social, and functional impairments among Korean adolescents with acne. METHODS: Five hundred four middle school students (13~16 years) participated. The severity of acne was graded by visual examination using the Korean Acne Grading System. Self-reported questionnaires, including subjective acne severity rating, the Self Image Questionnaire, the Rosenberg Self-Esteem Questionnaire, the Index of Peer Relations, and the Beck Depression Inventory were used to assess psychologic status. RESULTS: There was a prevalence of acne in 78.9% of the study samples, with 10.2% of students having moderate-to-severe acne. Acne was more prevalent and severe in boys than girls. Participants with severe acne and girls had higher levels of emotional and social impairments. The longer the acne persisted, the more stress the students felt. The degree of stress and extent of self-image impairment were related to subjective severity more than objective grading. CONCLUSION: Acne is a common disorder among Korean adolescents and appears to have a considerable impact on mental health. Dermatologists should be aware of the importance of basic psychosomatic treatment in conjunction with early medical, educational intervention in the management of acne.