Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 41
Filtrar
Más filtros

Banco de datos
País/Región como asunto
Tipo del documento
Intervalo de año de publicación
1.
J Environ Manage ; 350: 119491, 2024 Jan 15.
Artículo en Inglés | MEDLINE | ID: mdl-38007932

RESUMEN

Agriculture is a main driver of land-cover change globally resulting in decreased biodiversity, increased carbon emissions, and land desertification. Environmental best management practices reduce risk to the environment caused by agricultural operations. However, the adoption of environmental best management practices by farmers often is lower than what would be possible. While prior studies have investigated determinants of environmental best management practices, it is not well understood how social psychological drivers of various best management practices may be modified by contextual factors. To help close this knowledge gap, we conducted a large-scale survey of Ontario farmers investigating how social psychological factors and resource constraints combine to determine adoption of farm forests, riparian buffers and windbreaks, and how these relationships are modified by farmer demographics and farm characteristics. We analyzed survey responses of 490 farmers with structural equation modeling using the Theory of Planned Behavior as theoretical framework. Our results suggest that perceived benefits of environmental best management practices are of relatively low impact on best management practice adoption. Beliefs of a personal obligation for adoption and the perception of the capacity for adoption consistently were of higher impact, with lack of labor as main constraint. The relationships of perceived benefits and social norms with adoption were modified by farmer income, education, and age, as well as by the distance between a farm and the nearest settlement. However, the relationship of control beliefs with adoption was not affected by any contextual factors. We conclude that the improvement of programs in support of labor availability may have positive impacts on the adoption of the investigated environmental best management practices.


Asunto(s)
Agricultura , Agricultores , Humanos , Agricultores/psicología , Agricultura/métodos , Granjas , Encuestas y Cuestionarios , Biodiversidad
2.
J Clin Gastroenterol ; 56(2): 148-153, 2022 02 01.
Artículo en Inglés | MEDLINE | ID: mdl-33471484

RESUMEN

GOAL: The aim was to assess proactive specialized inflammatory bowel diseases (IBD) emergency department (ED) consultation and multidisciplinary IBD team (IBD-MDT) intervention on IBD-related patient outcomes after discharge. BACKGROUND: Despite advances in patient care, IBD-related ED visits have increased and substantially contribute to the IBD burden. METHODS: Consecutive patients with IBD (below 50 y) who visited the ED during November 2017 to April 2018 (intervention group) were compared with patients with IBD that visited the same ED during 2014 to 2017 (standard-care group). The primary outcomes were hospitalization and ED revisits at 30, 90, and 180 days. RESULTS: The intervention group (45 patients, mean age 32.43±8.6 y, 57.8% male) and the standard-care group (237 patients) had comparable baseline characteristics, including age, sex, and IBD type, and similar rates of hospital admissions from the ED (46.7% vs. 38.8%, P=0.32). The intervention group more frequently underwent computed tomography (40% vs. 8%, P<0.001) and surgical interventions (13.3% vs. 0.8%, P<0.001) within the same hospital admission, compared with the standard-care group. In the intervention group, 24 patients were discharged from the ED, of whom 17 patients visited the IBD clinic (median 5 d postdischarge) and the majority were referred to ambulatory IBD-MDT services (dietitian: 46.7%, psychologist: 6.7%, advanced endoscopist: 8.9%, and proctology services: 6.7%). The intervention group had significantly fewer ED revisits than the standard-care group (30 d: 4.4% vs. 19.8%, P=0.013; 90 d: 4.4% vs. 35.9%, P<0.001; 180 d: 6.7% vs. 43%, P<0.001). CONCLUSION: Proactive specialized ED assessments and IBD-MDT interventions after a hospital discharge were preferable; they significantly reduced the ED revisit rate for at least 6 months.


Asunto(s)
Enfermedades Inflamatorias del Intestino , Alta del Paciente , Adulto , Cuidados Posteriores , Servicio de Urgencia en Hospital , Femenino , Hospitalización , Humanos , Enfermedades Inflamatorias del Intestino/diagnóstico , Enfermedades Inflamatorias del Intestino/terapia , Masculino , Adulto Joven
3.
J Environ Manage ; 310: 114723, 2022 May 15.
Artículo en Inglés | MEDLINE | ID: mdl-35220099

RESUMEN

Wetlands provide critical ecosystem services including flood mitigation and habitat for diverse species, but globally, many wetlands have been destroyed. In urban areas and surrounding urban-rural fringes, many lost wetlands have been indirectly replaced with stormwater management (SWM) ponds. SWM ponds are designed to manage urban stormwater and contaminants, but only provide limited ecosystem services. In our study area, historic extent of wetland loss is partially documented, while more recent losses and SWM pond creation have not been fully reported. We examine wetland loss and SWM pond creation in seven southern Ontario (Canada) municipalities from 2002 to 2010. We then apply a Markov model to project future extent of wetland losses and SWM pond creation, with and without effects of specific land use and land cover types. We find that from 2002 to 2010, 95.5 ha of wetlands were lost, with most being smaller than 2 ha in size. A total area of 111.6 ha of SWM ponds was created, but on average, created SWM ponds were smaller than lost wetlands. Our projections to 2026 suggest wetland losses of 438.1 ha and SWM pond creation of 293.8 ha. We suggest a need for more stringent wetland protection policies to conserve wetlands that still exist in growing municipalities, especially smaller wetlands. Lack of such protection will weaken provisioning of wetland-related ecosystem services, which are more critical than ever in a changing climate.


Asunto(s)
Ecosistema , Urbanización , Humedales , Ciudades , Ontario , Estanques
4.
Medicina (Kaunas) ; 58(5)2022 May 13.
Artículo en Inglés | MEDLINE | ID: mdl-35630078

RESUMEN

Background and Objectives: Injuries associated with electric bikes (E-bikes) and powered scooters (P-scooters) have increased yearly worldwide. We aimed to evaluate the impact of pre-existing comorbidities on the probability of hospitalization for injuries in riders of E-bikes and P-scooters. Materials and Methods: A retrospective cross-sectional study design was used. The cohort included patients referred to the emergency department (ED) of a tertiary medical center in 2014-2020 for injuries sustained while riding an E-bike or P-scooter. Data were collected from the medical files on demographics, clinical characteristics including pre-existing comorbidities and permanent use of medications, and injury characteristics. Findings were compared between patients referred for hospitalization from the ED and patients discharged home. Results: Of the 1234 patients who met the inclusion criteria, 202 (16.4%) had a prior medical condition and 167 (13.5%) were taking medication on a permanent basis. A significant relationship was found between hospitalization and having a medical condition (𝜒2(1) = 9.20, p = 0.002) or taking medication on a permanent basis (𝜒2(1) = 6.24, p = 0.01). Hospitalization for injuries was more likely in patients with a comorbidity (27.8%) than those without a comorbidity (15.5%), and in patients who were on permanent drug therapy (22.2%) than in patients who were not (12.9%). Surprisingly, anticoagulant intake specifically had no effect on the probability of hospital admission. Conclusions: Patients with comorbidities have a higher incidence of hospitalization for E-bike- and P-scooter-associated injuries. Therefore, physicians may take into account comorbidities for the effective management of this patient group's injuries.


Asunto(s)
Ciclismo , Hospitalización , Comorbilidad , Estudios Transversales , Humanos , Estudios Retrospectivos
5.
Medicina (Kaunas) ; 58(7)2022 Jul 14.
Artículo en Inglés | MEDLINE | ID: mdl-35888653

RESUMEN

Background and Objectives: The worldwide increase in electric bike (E-bike) and powered scooter (P-scooter) use in recent years has been accompanied by an increase in associated injuries to riders. The aim of this study was to evaluate trends in the incidence and types of E-bikes and P-scooter-related injuries in riders evacuated to a tertiary ED. Materials and Methods: A retrospective cross-sectional design was used. The cohort included 1234 patients referred to the emergency department (ED) of a tertiary medical center in 2014-2020 for injuries sustained while riding an E-bike or P-scooter. Demographic, clinical, and injury data were collected from the medical files, and injury rates were evaluated over time. Results: The results showed that the annual number of ED visits by injured E-bike and P-scooter riders increased steadily over the study period concomitant with an increase in ED referrals for hospitalization, indicating severe injury. The upper and lower extremities were the most frequent anatomic sites of injury in every year of the study, with variations among the different age groups. Conclusions: Our findings suggest a need for safety regulations for riders who operate two-wheel powered vehicles, such as licensing requirements and mandatory protective gear, especially for anatomic sites most at risk.


Asunto(s)
Ciclismo , Servicio de Urgencia en Hospital , Accidentes de Tránsito , Estudios Transversales , Humanos , Incidencia , Estudios Retrospectivos
6.
Mediators Inflamm ; 2021: 8872686, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33814983

RESUMEN

BACKGROUND AND AIMS: Plasma levels of soluble triggering receptor expressed on myeloid cells (sTREM-1) reflect innate immune cell activation. We sought to evaluate sTREM-1 levels in patients with acute coronary syndrome (ACS) and their predictive value for disease severity and outcome. METHODS: Plasma sTREM-1 levels were prospectively measured by ELISA in 121 consecutive patients with new-onset (≤24 h) chest pain at arrival to the emergency department (ED) and 73 healthy controls. Secondary endpoints were the association of plasma levels of sTREM-1 with day 30 and month 6 major adverse cardiovascular events (MACE) defined as death, ACS, stroke, and need for coronary revascularization, as well as with CAD severity. The primary endpoint of the study was the association of plasma sTREM-1 level at the time of admission to the ED with a diagnosis of ACS at day 30. RESULTS: Fifty-nine patients (48.7%) were diagnosed with ACS and 62 (51.3%) with nonspecific chest pain (NSCP). Median plasma sTREM-1 level at admission was significantly higher in the ACS group than the NSCP group and the control group (539.4 ± 330.3 pg/ml vs. 432.5 ± 196.4 pg/ml vs. 230.1 ± 85.5 pg/ml, respectively; P < 0.001) and positively correlated with the number of stenosed/occluded coronary arteries on angiography (P < 0.001). On logistic regression analysis, higher sTREM-1 levels predicted definite ACS vs. NSCP determined on day 30 (OR 1.29, 95% CI 1.07-1.54, P = 0.01) as well as with recurrent ACS (P = 0.04) and stroke (P = 0.02) at 6 months. CONCLUSIONS: Plasma sTREM-1 levels are significantly elevated in patients with ACS and might serve as a biomarker differentiating ACS from NSCP in the ED as well as an inflammatory biomarker for coronary artery disease severity and outcome.


Asunto(s)
Síndrome Coronario Agudo , Receptor Activador Expresado en Células Mieloides 1/sangre , Síndrome Coronario Agudo/metabolismo , Biomarcadores , Humanos , Células Mieloides/metabolismo , Índice de Severidad de la Enfermedad
7.
Environ Manage ; 67(2): 308-322, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33226452

RESUMEN

Climate change effects and increasing levels of imperviousness, cause many urban areas globally to experience larger rainfall runoff volumes that need to be managed to protect property and infrastructure, and avoid environmental pollution. Conventionally engineered, 'grey' stormwater infrastructure often is outdated and unable to control these increased runoff volumes. Green stormwater infrastructure (GSI) can complement grey infrastructure, but public land for its installation is limited. Consequently, municipalities often look to residential properties to install GSI at the lot-level. While many studies have been conducted in the engineering aspects of GSI, less is known about what determines residents' decisions to install GSI on their properties. To help close this knowledge gap, we conducted a survey of social-psychological determinants of residential GSI implementation using the Theory of Planned Behavior as theoretical framework, and analyzing our data with partial least squares path modeling. Results from three neighborhoods of our case study area suggest that residents' decisions to install GSI largely are determined by social norms and perceived control factors such as available finances and time. However, residents' beliefs and attitudes toward the effectiveness and attractiveness of GSI did not seem to play a significant role. Neighborhood characteristics including local flooding history did not seem to affect residents' decisions about GSI installation either. We recommend creation of effective municipal education and outreach programs regarding urban stormwater management that speak to residents' shared responsibility and options for addressing this issue, as well as creation of financial instruments that provide meaningful subsidies for residential GSI adoption.


Asunto(s)
Inundaciones , Lluvia , Ciudades , Cambio Climático , Normas Sociales
8.
J Emerg Med ; 58(1): 54-58, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31926780

RESUMEN

BACKGROUND: Fecal occult blood testing (FOBT) was developed to detect microscopic bleeding caused by colorectal neoplasms. The role of FOBT in the emergency department (ED) is typically used for 5 different clinical workups: trauma, anemia, syncope, hypotension, and before the administration of systemic anticoagulants or thrombolytics. OBJECTIVE: We scrutinized the literature to assess the utility of FOBT for its 5 most common applications in the emergent setting. DISCUSSION: Logic and clinical evidence advocating for FOBT usage in the aforementioned situations are lacking. The test itself requires specific drug and dietary restrictions that are often violated or never met when patients present to the ED with acute pathologies. In addition, the poor sensitivity and specificity of the test in these scenarios dictate that neither a negative nor positive FOBT should change the subsequent clinical workup of patients presenting to the ED. CONCLUSION: Clinical decision making should seldom be predicated on the results of a FOBT in the ED setting.

9.
Pain Manag Nurs ; 20(6): 633-638, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31175043

RESUMEN

BACKGROUND: Pain is a widespread problem, affecting both men and women; studies have found that women in the emergency department receive analgesic medication and opioids less often compared with men. AIMS: The aim of this study was to examine the administration and management of analgesics by the medical/paramedical staff in relation to the patients' gender, and thereby to examine the extent of gender discrimination in treating pain. DESIGN: This is a single-center retrospective cohort study that included 824 patients. SETTINGS: Emergency department of tertiary hospital in Israel. PARTICIPANTS/SUBJECTS: The patients stratified by gender to compare pain treatments and waiting times between men and women in renal colic complaint. METHODS: As an acute pain model, we used renal colic with a nephrolithiasis diagnosis confirmed by imaging. We recorded pain level by Visual Analog Scale (VAS) scores and number of VAS examinations. Time intervals were calculated between admissions to different stations in the emergency department. We recorded the number of analgesic drugs administered, type of drugs prescribed, and drug class (opioids or others). RESULTS: A total of 824 patients (414 women and 410 men) participated. There were no significant differences in age, ethnicity, and laboratory findings. VAS assessments were higher in men than in women (6.43 versus 5.90, p = .001, respectively). More men than women received analgesics (68.8% versus 62.1%, p = .04, respectively) and opioids were prescribed more often for men than for women (48.3 versus 35.7%, p = .001). The number of drugs prescribed per patient was also higher in men compared with women (1.06 versus 0.93, p = .03). A significant difference was found in waiting time length from admission to medical examination between non-Jewish women and Jewish women. CONCLUSIONS: We found differences in pain management between genders, which could be interpreted as gender discrimination. Yet these differences could also be attributed to other factors not based on gender discrimination but rather on gender differences.


Asunto(s)
Manejo del Dolor/normas , Cólico Renal/terapia , Sexismo/psicología , Dolor Agudo/tratamiento farmacológico , Adulto , Anciano , Analgésicos/uso terapéutico , Estudios de Cohortes , Servicio de Urgencia en Hospital/organización & administración , Servicio de Urgencia en Hospital/normas , Servicio de Urgencia en Hospital/estadística & datos numéricos , Femenino , Humanos , Israel , Masculino , Persona de Mediana Edad , Manejo del Dolor/métodos , Manejo del Dolor/estadística & datos numéricos , Dimensión del Dolor/estadística & datos numéricos , Cólico Renal/complicaciones , Cólico Renal/psicología , Estudios Retrospectivos , Sexismo/estadística & datos numéricos
10.
J Emerg Med ; 55(2): 185-191, 2018 08.
Artículo en Inglés | MEDLINE | ID: mdl-29858143

RESUMEN

BACKGROUND: Medical treatment of hunger-strike patients, especially those in incarceration facilities, may pose clinical and treatment challenges for the treating physicians. OBJECTIVE: The aim of our study is to describe the epidemiology and clinical and laboratory characteristics of hunger-strike prisoners presenting to the emergency department (ED) and to describe etiologies of hospitalization and complications among this group. METHOD: We retrospectively examined clinical and laboratory manifestations of 50 hunger-strike prisoners who were referred for evaluation to the ED after a longstanding fast. RESULTS: After a mean of 38 (28-44) days of a hunger strike, the most common complaints were chest pain and abdominal pain (14/60 [23.3%], 13/60 [21.6%], respectively). Mean weight loss percentage was 18.5%, and most patients were bradycardic (25/40 [62.5%]), and some hypothermic (16/50, [32%]). We describe several laboratory disturbances observed in these patients; leukopenia was the most common hematologic manifestation (31/50 [62%]), and a prolonged international normalized ratio was observed in 12/29 (41.3%) patients. We hospitalized 12% of the patients; the most common hospitalization cause was bradycardia (3/6 [50%]). CONCLUSIONS: Our study found that the most common clinical symptom was chest pain, which has not been previously reported among hunger strikers. We observed a substantial number of laboratory disturbances due to muscle wasting and protein loss and due to presumed vitamin and micronutrient deficiencies. We suggest monitoring electrocardiograms for heart rate, blood count, chemistry, coagulation tests, and vitamin levels.


Asunto(s)
Ayuno/metabolismo , Hambre/fisiología , Prisioneros/psicología , Adulto , Árabes/psicología , Árabes/estadística & datos numéricos , Bradicardia/etiología , Dolor en el Pecho/etiología , Servicio de Urgencia en Hospital/organización & administración , Ayuno/efectos adversos , Humanos , Israel , Leucopenia/etiología , Masculino , Prisioneros/estadística & datos numéricos , Estudios Retrospectivos
11.
12.
J Emerg Med ; 51(4): 440-446, 2016 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-27452987

RESUMEN

BACKGROUND: Despite evidence-based recommended weight-based (WB) dosing of diltiazem for the initial treatment of atrial fibrillation (AF) with rapid ventricular response (RVR), many providers utilize lower initial doses of diltiazem. OBJECTIVE: We sought to determine whether a low, standard dose of diltiazem is noninferior to WB diltiazem as an initial bolus dose in the treatment of AF with RVR. METHODS: This retrospective review included patients who presented to the emergency department (ED) of an urban, academic tertiary medical center experiencing AF with RVR from November 2010 to August 2014. Adult patients were categorized by the dose of diltiazem received; 10 mg standard dose or 0.2-0.3 mg/kg WB dose. The primary outcome of successful treatment was defined as a composite of the following parameters 15 min after the initial bolus dose: heart rate (HR) < 100 beats/min, reduction of HR ≥ 20%, or a conversion to normal sinus rhythm. RESULTS: Four hundred and fifty-six patients who received diltiazem were included for study evaluation (standard dose: n = 255 patients, WB: n = 201 patients). Baseline characteristics, medical history, and medication use before ED presentation were similar between the groups. Significant differences at baseline between the groups included weight and HR at presentation. The primary outcome of successful treatment was attained in 60.8% of the standard dose patients and 68.7% of the WB patients (p = 0.082). CONCLUSIONS: In patients presenting to the ED, we found that standard dose diltiazem was noninferior to WB dosing in the initial treatment of AF with RVR.


Asunto(s)
Fibrilación Atrial/tratamiento farmacológico , Peso Corporal , Bloqueadores de los Canales de Calcio/administración & dosificación , Diltiazem/administración & dosificación , Anciano , Anciano de 80 o más Años , Servicio de Urgencia en Hospital , Femenino , Frecuencia Cardíaca/efectos de los fármacos , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento
14.
Int J Surg ; 110(1): 144-150, 2024 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-37800592

RESUMEN

BACKGROUND: The detection of haemorrhage in trauma casualties may be delayed owing to compensatory mechanisms. This study aimed to evaluate whether the cardiovascular reserve index (CVRI) on arrival detects massive haemorrhage and predicts haemorrhage development in trauma casualties. METHODS: This was an observational prospective cohort study of adult casualties (≥18 years) who were brought to a single level-1 trauma centre, enroled upon arrival and followed until discharge. Vital signs were monitored on arrival, from which the CVRI and shock index were retrospectively calculated (blinded to the caregivers). The outcome measure was the eventual haemorrhage classification group: massive haemorrhage on arrival (MHOA) (defined by massive transfusion on arrival of ≥6 [O+] packed cells units), developing haemorrhage (DH) (defined by a decrease in haemoglobin >1 g/dl in consecutive tests), and no significant haemorrhage noted throughout the hospital stay. The means of each variable on arrival by haemorrhage group were evaluated using the analysis of variance. The authors evaluated the detection of MHOA in the entire population and the prediction of DH in the remainders (given that MHOA had already been detected and treated) by C-statistic predefined strong prediction by area under the curve (AUC) greater than or equal to 0.8, P less than or equal to 0.05. RESULTS: The study included 71 patients (after exclusion): males, 82%; average age 37.7 years. The leading cause of injuries was road accident (61%). Thirty-nine (54%) patients required hospital admission; distribution by haemorrhage classification: 5 (7%) MHOA, 5 (7%) DH, and 61 (86%) no significant haemorrhage. Detection of MHOA found a strong predictive model by CVRI and most variables (AUC 0.85-1.0). The prediction of DH on arrival showed that only lactate (AUC=0.88) and CVRI (0.82) showed strong predictive model. CONCLUSIONS: CVRI showed a strong predictive model for detection of MHOA (AUC>0.8) as were most other variables. CVRI also showed a strong predictive model for detection of DH (AUC=0.82), only serum lactate predicted DH (AUC=0.88), while all other variables were not found predictive. CVRI has advantages over lactate in that it is feasible in pre-hospital and mass casualty settings. Moreover, its repeatability enables detection of deteriorating trend. The authors conclude that CVRI may be a useful additional tool in the evaluation of haemorrhage.


Asunto(s)
Centros Traumatológicos , Heridas y Lesiones , Adulto , Masculino , Humanos , Estudios Retrospectivos , Estudios Prospectivos , Hemorragia/diagnóstico , Hemorragia/etiología , Lactatos , Heridas y Lesiones/complicaciones , Heridas y Lesiones/diagnóstico
15.
Clin Microbiol Infect ; 29(9): 1159-1165, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37270059

RESUMEN

OBJECTIVES: To assess the performance of a test (called BV), integrating the blood levels of three immune proteins into a score, to differentiate bacterial from viral infection among adults with suspected lower respiratory tract infection (LRTI). METHODS: Prospective diagnostic accuracy study, enrolling febrile adults >18 years with LRTI signs or symptoms for less than 7 days presenting to several hospitals' emergency departments in Israel. The main exclusion criterion was immunodeficiency. Reference standard diagnosis (bacterial/viral/indeterminate) was based on three experts independently reviewing comprehensive patient data including follow-up data. BV generated three results: viral infection or other nonbacterial condition (0 ≤ score < 35), equivocal (35 ≤ score ≤ 65) and bacterial infection including co-infection (65 < score ≤ 100). BV performance was assessed against the reference standard with indeterminate reference standard and equivocal BV cases removed. RESULTS: Of 490 enrolled patients, 415 met eligibility criteria (median age 56 years, interquartile range 35). The reference standard classified 104 patients as bacterial, 210 as viral and 101 as indeterminate. BV was equivocal in 9.6% (30/314). Excluding indeterminate reference standard diagnoses and equivocal BV results, BV's sensitivity for bacterial infection was 98.1% (101/103; 95% confidence interval 95.4-100), specificity 88.4% (160/181; 83.7-93.1) and negative predictive value 98.8% (160/162; 97.1-100). DISCUSSION: BV exhibited high diagnostic performance for febrile adults with suspected LRTI among patients with reference standard diagnoses of bacterial or viral LRTI.


Asunto(s)
Infecciones Bacterianas , Infecciones del Sistema Respiratorio , Virosis , Humanos , Adulto , Persona de Mediana Edad , Proteína C-Reactiva/análisis , Interferón gamma , Biomarcadores , Estudios Prospectivos , Ligandos , Sensibilidad y Especificidad , Infecciones Bacterianas/diagnóstico , Infecciones del Sistema Respiratorio/diagnóstico , Infecciones del Sistema Respiratorio/microbiología , Virosis/diagnóstico , Bacterias , Fiebre , Factor de Necrosis Tumoral alfa
16.
Headache ; 52(4): 573-81, 2012 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21848948

RESUMEN

BACKGROUND: Religious fasting is associated with headache. This has been documented as "Yom Kippur headache" and "first of Ramadan headache." Etoricoxib, a Cox-2 inhibitor with a 22-hour half-life, has been shown effective in preventing fasting headache when taken just prior to the 25-hour Yom Kippur fast. We hypothesized that etoricoxib would also be effective in preventing headache during Ramadan, despite the different characteristics of the fast. METHODS: We performed a double-blind randomized prospective crossover trial of etoricoxib 90mg vs placebo, taken just prior to the onset of fasting, during the first 2 weeks of Ramadan 2010. Healthy adults aged 18-65 years were enrolled. Demographics, headache history and a daily post-fast survey were collected. We compared incidence, time of onset, and intensity of headache on each day and side effects in control and treatment groups. RESULTS: We enrolled 222 patients and 189 completed the post-fast questionnaire (87%). Etoricoxib reduced the incidence of "first of Ramadan" headache by 54% (46% in placebo group [n=92] vs 21% [n=96] in etoricoxib group) (P<.0001, OR 3.19 [95% CI 1.68-6.06]). For days 1-6, the mean number of headache days for the placebo group was 1.60 (n=92) and for the treatment group the mean was 0.86 (n=99) headache days (P=.003). Median severity of headache in the treatment group was significantly lower. In the second week, there was no significant difference in incidence of headache between groups, and the incidence of headache in the placebo group dropped markedly over time. CONCLUSION: Etoricoxib 90mg taken prior to a 15-hour ritual fast decreases incidence of and attenuates headache during the first 5 days of the month of Ramadan.


Asunto(s)
Inhibidores de la Ciclooxigenasa 2/administración & dosificación , Ayuno/efectos adversos , Cefalea/tratamiento farmacológico , Cefalea/etiología , Islamismo , Piridinas/administración & dosificación , Sulfonas/administración & dosificación , Adulto , Estudios Cruzados , Inhibidores de la Ciclooxigenasa 2/uso terapéutico , Método Doble Ciego , Etoricoxib , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Piridinas/uso terapéutico , Sulfonas/uso terapéutico , Resultado del Tratamiento , Adulto Joven
17.
Medicine (Baltimore) ; 101(36): e30555, 2022 Sep 09.
Artículo en Inglés | MEDLINE | ID: mdl-36086698

RESUMEN

To evaluate the daily output measures of the emergency department (ED) in association with seasonality and the day of the week. A retrospective cohort of ED visits to tertiary medical centers between 2016 and 2020. The research unit was each day during the study period. The independent variables were season and day of the week. The dependent variables were ED visits, admission and dropout rates, and duration of ED discharge. The comparison of means was evaluated using ANOVA. Statistical significance was set at P < .05. There were 1826 days, 792 thousand visits, 58% were female. Admission rate 28%, duration to discharge 3.8 h, dropout rate 2%. The average daily visits by season ranged from 101% of the overall average in autumn to 97% in spring. Average daily visits by day of the week were significantly different, with the highest on Sunday (Israel's first working day of the week), 124% of the overall daily average, and the lowest on Saturday (weekly day off) with 70%. Saturdays had the highest admission rate of 30% and 28% of the overall rate. There was a moderate dependency between the ED duration and discharge, with a dropout rate of r2 = 0.19. The average daily visits were not affected by season but differed considerably by day of the week. Admission rates varied slightly by season but were similar by day of the week apart from Saturdays. This may be attributable to the case mix on Saturdays or less restriction to admit when the number of visits is low. We recommended each Emergency Department to evaluate its daily output measures dependency with seasonality and day of the week for operational optimization.


Asunto(s)
Servicio de Urgencia en Hospital , Hospitalización , Femenino , Humanos , Masculino , Alta del Paciente , Estudios Retrospectivos , Estaciones del Año
18.
J Womens Health (Larchmt) ; 31(7): 926-931, 2022 07.
Artículo en Inglés | MEDLINE | ID: mdl-35501966

RESUMEN

Objectives: The HEART Pathway is a diagnostic protocol designed to identify low-risk patients with chest pain who can be safely discharged from the emergency department (ED) without hospitalization. Studies have reported a negative bias in identifying myocardial ischemia in females versus males and a different clinical pattern of cardiac ischemia across genders. This study sought to determine if the HEART Pathway recommendations are affected by negative bias in females. Materials and Methods: A retrospective cohort study was conducted in the ED of an academic tertiary medical center. Admission/discharge decisions made by physicians in male and female patients presenting with chest pain in 4/2014-7/2019 were compared with HEART Pathway protocol predictions. Probabilities were estimated with logistic regression analysis, and odds ratios and 95% confidence intervals were calculated. Results: The cohort included 772 patients, 485 male (63%) and 287 female (37%), of median age 54 years. On the basis of their presenting symptoms, 278 patients (36%) were admitted by the ED physician and 494 (64%) were discharged. Using the HEART Pathway protocol, 227 patients (29.4%) would be expected to be admitted and 545 (70.6%) discharged. The real-life admission rate was higher than possible with the HEART Protocol (p = 0.001). In a regression model, male sex was a significant factor favoring admission among the patients for whom the HEART Pathway predicted admission (p = 0.007). Conclusions: As the HEART Pathway is a validated risk-stratification tool, there is a high likelihood that serious coronary artery disease may be overlooked in women, even those who seek timely medical assistance.


Asunto(s)
Enfermedad de la Arteria Coronaria , Caracteres Sexuales , Dolor en el Pecho/diagnóstico , Enfermedad de la Arteria Coronaria/diagnóstico , Electrocardiografía/métodos , Servicio de Urgencia en Hospital , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Medición de Riesgo/métodos
19.
Healthcare (Basel) ; 10(6)2022 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-35742077

RESUMEN

The growing popularity of E-bikes and P-scooters has led to their increasing involvement in injuries. This study sought to evaluate the impact of drug and alcohol consumption on hospitalization rates for electric-vehicle-associated injuries. A retrospective cross-sectional study design was used, including patients evacuated to the emergency department (ED) of a tertiary medical center in 2014−2020 for injuries sustained while riding E-bikes or P-scooters. Data on clinical characteristics were collected from the medical files, including pre-accident usage of alcohol or drugs. Of the 1234 patients (75.7% male) who met the inclusion criteria, 90 (7.3%) were hospitalized. The mean (SD) number of admission days was 5.44 (±0.12). Alcohol consumption was associated with 2.2% of injuries and drug use with 0.6%. Patients who rode under the influence of alcohol were significantly more likely to be hospitalized than discharged (6.7% vs. 1.8%, χ2 (2) =19.25, p < 0.001); the odds ratio was 14.1. A similar association with hospitalization was found for drug use (χ2 (2) = 7.83, p = 0.02). Riding an E-bike or P-scooter under the influence of alcohol or drugs increases the probability of severe injury requiring hospital admission. These results should prompt the relevant authorities to initiate effective legislation of alcohol and drug use.

20.
Open Access Emerg Med ; 14: 557-562, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36217328

RESUMEN

Objective: Survival after out-of-hospital cardiac arrest (OHCA) depends on multiple factors, mostly quality of chest compressions. Studies comparing manual compression with a mechanical active compression-depression device (ACD) have yielded controversial results in terms of outcomes and injury. The aim of the present study was to determine whether out-of-hospital ACD cardiopulmonary resuscitation (CPR) use is associated with more skeletal fractures and/or internal injuries than manual compression, with similar duration of cardiopulmonary resuscitation (CPR) between the groups. Methods: The cohort included all patients diagnosed with out-of-hospital cardiac arrest (OHCA) at a tertiary medical center between January 2018 and June 2019 who achieved return of spontaneous circulation (ROSC). The primary outcome measure was the incidence of skeletal fractures and/or internal injuries in the two groups. Secondary outcome measures were clinical factors contributing to skeletal fracture/internal injuries and to achievement of ROSC during CPR. Results: Of 107 patients enrolled, 45 (42%) were resuscitated with manual chest compression and 62 (58%) with a piston-based ACD device (LUCAS). The duration of chest compression was 46.0 minutes vs. 48.5 minutes, respectively (p=0.82). There were no differences in rates of ROSC (53.2% vs.50.8%, p=0.84), cardiac etiology of OHCA (48.9% vs.43.5%, p=0.3), major complications (ribs/sternum fracture, pneumothorax, hemothorax, lung parenchymal damage, major bleeding), or any complication (20.5% vs.12.1%, p=0.28). On multivariate logistic regression analysis, factors with the highest predictive value for ROSC were cardiac etiology (OR 1.94;CI 2.00-12.94) and female sex (OR 1.94;CI 2.00-12.94). Type of arrhythmia had no significant effect. Use of the LUCAS was not associated with ROSC (OR 0.73;CI 0.34-2.1). Conclusion: This is the first study to compare mechanical and manual out-of-hospital chest compression of similar duration to ROSC. The LUCAS did not show added benefit in terms of ROSC rate, and its use did not lead to a higher risk of traumatic injury. ACD devices may be more useful in cases of delayed ambulance response times, or events in remote locations.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA