Asunto(s)
Intubación Intratraqueal , Enfermedades Respiratorias/terapia , Traqueotomía , Niño , Humanos , NarizAsunto(s)
Manejo del Dolor , Cuidados Paliativos , Analgesia , Cordotomía , Cresoles/administración & dosificación , Humanos , Soluciones Hipertónicas/administración & dosificación , Inyecciones Espinales , Neoplasias/terapia , Dolor/tratamiento farmacológico , Dolor/cirugía , Fenoles/administración & dosificación , Cloruro de Sodio/administración & dosificaciónRESUMEN
Transphenoidal ablation of the pituitary gland by the injection of alcohol is used for the relief of wide-spread cancer pain. A technique is described in which a cryoprobe is passed through a transphenoidal needle and a number of lesions produced within the gland. It is suggested that this method of pituitary ablation may prove to be as effective but accompanied by fewer complications than the injection of alcohol.
Asunto(s)
Criocirugía/instrumentación , Hipofisectomía/métodos , Dolor Intratable/cirugía , HumanosRESUMEN
The use of trifluoperazine and amitriptyline in the treatment of pain is described. Of 12 patients who were suffering chronic pain from various causes, 8 obtained a major degree of relief from the use of this combination of drugs.
Asunto(s)
Amitriptilina/uso terapéutico , Dolor Intratable/prevención & control , Trifluoperazina/uso terapéutico , Adulto , Anciano , Enfermedad Crónica , Quimioterapia Combinada , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
The effect of high inspired carbon dioxide concentrations and i.v. ethyl alcohol on the temperature at which cardiac arrest occurred was studied in chacma baboons. Alcohol-treated baboons developed cardiac arrest at a temperature of 24.3 degrees C (SD +/- 0.85) and control animals at 27 degrees C (SD +/- 1.30). There were no signs of cardiac failure before the occurrence of ventricular fibrillation.
Asunto(s)
Temperatura Corporal/efectos de los fármacos , Dióxido de Carbono/farmacología , Etanol/farmacología , Paro Cardíaco/etiología , Animales , Peso Corporal , Etanol/sangre , Haplorrinos , Masculino , PapioRESUMEN
The organic and psychological problems of patients suffering from chronic abdominal pain are described and three case histories of patients who had undergone multiple surgery for their abdominal pain are presented. All three were treated by lumbar sympathetic lysis, resulting in relief of their pain. The possible reasons for this success are discussed.
Asunto(s)
Abdomen , Manejo del Dolor , Fenoles/uso terapéutico , Sistema Nervioso Simpático/efectos de los fármacos , Adulto , Enfermedad Crónica , Femenino , Humanos , Lidocaína , Región Lumbosacra , Masculino , Persona de Mediana Edad , Bloqueo NerviosoRESUMEN
1. Previous clinical and experimental reports have suggested that the systemic administration of ethyl alcohol permits lower body temperatures before the onset of hypothermic cardiac arrest. 2. In the investigations described here, the effect of ethyl alcohol on the temperature at which cardiac arrest occurred in rats, guinea-pigs and isolated rat hearts was studied. Comparison was also made of the difference between pulmonary ventilation with air and with 5% carbon dioxide in oxygen. 3. The results demonstrated that both the administration of ethyl alcohol and ventilation with 5% carbogen reduced the cardiac arrest temperature of rats. Ethyl alcohol did not influence the cardiac arrest temperature of guinea-pigs nor of isolated rat hearts.
Asunto(s)
Dióxido de Carbono , Frío , Etanol , Paro Cardíaco , Animales , Temperatura Corporal , Dióxido de Carbono/farmacología , Etanol/farmacología , Cobayas , Corazón/efectos de los fármacos , Masculino , RatasRESUMEN
The effect of ethanol on the cerebro-spinal fluid pressure of six baboons is described. A biphasic response is shown to the intravenous infusion with a mean pressure fall of 3.1 mmHg. It is suggested that both the diuretic effect and the effect of alcohol on cerebral blood flow may be factors involved in the pressure fall.
Asunto(s)
Etanol/farmacología , Presión Intracraneal/efectos de los fármacos , Animales , Presión Sanguínea/efectos de los fármacos , Presión Venosa Central/efectos de los fármacos , Depresión Química , Haplorrinos , Masculino , Papio , Factores de TiempoRESUMEN
A review of 50 cases of ruptured uterus revealed that important measures to prevent this serious complication are: good antenatal care; careful attention to patients who have had a previous Caesarean section; the correct management of cephalopelvic disproportion in the multigravida; the recognition of the serious hazards of internal version in the management of transverse lie; and careful attention to detail in the use of oxytocin in the multigravida. The factors that were regarded as critical in maintaining a low maternal mortality rate in rupture of the uterus are also reviewed.
Asunto(s)
Rotura Uterina/prevención & control , Anestesia Obstétrica , Cesárea/efectos adversos , Femenino , Humanos , Histerectomía , Presentación en Trabajo de Parto , Oxitocina/efectos adversos , Paridad , Cuidados Posoperatorios , Embarazo , Atención Prenatal , Recurrencia , Resucitación , Factores de Tiempo , Rotura Uterina/epidemiología , Rotura Uterina/etiologíaRESUMEN
Pituitary ablation by the injection of alcohol through a transphenoidal needle has been practised for a number of years. In order to reduce the complications resulting from the spread of alcohol to neighbouring structures, a cryoprobe has been constructed which can be passed up through the needle into the gland and a series of localised lesions produced. The degree of pain relief is as good if not better than that obtained with alcohol. Only one instance of temporary blurring of vision resulted and hormonal disturbances were not seen. No difference was observed between the results obtained from the treatment of hormone-dependent and hormone-insensitive tumours. Pain caused in one patient by a benign tumour was unsuccessfully treated.
Asunto(s)
Criocirugía , Hipofisectomía/métodos , Metástasis de la Neoplasia/complicaciones , Dolor Intratable/cirugía , Criocirugía/efectos adversos , Femenino , Estudios de Seguimiento , Humanos , Hipofisectomía/efectos adversos , Masculino , Dolor Intratable/etiologíaRESUMEN
The analgesic properties of ethyl alcohol administered i.v. were investigated, using elevation of the pain threshold for applied somatic stimuli as an index. Alcohol proved markedly superior to saline in this respect and produced an effect equivalent to that of i.v. morphine.