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Int J Radiat Oncol Biol Phys ; 65(3): 824-9, 2006 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-16682137

RESUMEN

PURPOSE: To evaluate the impact of computed tomographic (CT) planning in comparison to clinical mark-up (CM) for palliative radiation of chest wall metastases. METHODS AND MATERIALS: In patients treated with CM for chest wall bone metastases (without conventional simulation/fluoroscopy), two consecutive planning CT scans were acquired with and without an external marker to delineate the CM treatment field. The two sets of scans were fused for evaluation of clinical tumor volume (CTV) coverage by the CM technique. Under-coverage was defined as the proportion of CTV not covered by the CM 80% isodose. RESULTS: Twenty-one treatments (ribs 17, sternum 2, and scapula 2) formed the basis of our study. Due to technical reasons, comparable data between CM and CT plans were available for 19 treatments only. CM resulted in a mean CTV under-coverage of 36%. Eleven sites (58%) had an under-coverage of >20%. Mean volume of normal tissues receiving >/=80% of the dose was 5.4% in CM and 9.3% in CT plans (p = 0.017). Based on dose-volume histogram comparisons, CT planning resulted in a change of treatment technique from direct apposition to a tangential pair in 7 of 19 cases. CONCLUSIONS: CT planning demonstrated a 36% under-coverage of CTV with CM of ribs and chest wall metastases.


Asunto(s)
Neoplasias Óseas/diagnóstico por imagen , Neoplasias Óseas/radioterapia , Simulación por Computador , Cuidados Paliativos/métodos , Planificación de la Radioterapia Asistida por Computador/métodos , Neoplasias Óseas/secundario , Clavícula/diagnóstico por imagen , Humanos , Estudios Prospectivos , Costillas/diagnóstico por imagen , Escápula/diagnóstico por imagen , Esternón/diagnóstico por imagen , Pared Torácica/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Carga Tumoral
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