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1.
Arthroplast Today ; 27: 101417, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38882467

RESUMEN

Background: Following total knee arthroplasty (TKA), normal knee kinematics are rarely replicated. Retention of both cruciate ligaments (bicruciate retaining TKA) has helped this. Postoperative posterior tibial slope (PPTS) may further affect ligament tension and kinematics. The objective of this study is to determine how changes between the preoperative posterior tibial slope (PTS) and PPTS affect knee kinematics. Methods: Twenty bicruciate retaining TKAs were performed using standard instrumentation. Fluoroscopic kinematic data were obtained during gait and a single knee bend. Differences (Δ) between radiographic measurements of preoperative and PPTS were correlated with in-vivo knee kinematics. Patients were separated into 2 groups based on their Δ values. Group I consisted of Δ values less than 0.7, indicating either a similar PPTS compared to preoperative PTS or a slightly flatter PPTS. Group II consisted of Δ values above 0.7, indicating a steepened PPTS. Results: Preoperative PTS values ranged from -0.5° to 11.2°, with an average of 5.0° ± 3.4°. PPTS values ranged from 3.0° to 12.1°, with an average of 7.1° ± 3.1°. Weight-bearing range of motion (WBROM) measured from 94° to 139°, and femorotibial axial rotation ranged from -2.9° to 17.3°. A t-test revealed average values for WBROM in Group IT (Δ < 0.7) to be significantly greater than those for Group IIT (Δ > 0.7) (P = .01). Conclusions: These findings indicate that either a PPTS approximating the preoperative PTS or a slightly flattened PPTS in comparison (Δ < 0.7) is associated with WBROM greater than 130°. Values for axial rotation and anterior sliding were not significantly associated with changes to the PTS.

2.
Neurol Neuroimmunol Neuroinflamm ; 11(4): e200243, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38630950

RESUMEN

Acute disseminated encephalomyelitis (ADEM) is one characteristic manifestation of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD). A previously healthy man presented with retro-orbital headache and urinary retention 14 days after Tdap vaccination. Brain and spine MRI suggested a CNS demyelinating process. Despite treatment with IV steroids, he deteriorated, manifesting hemiparesis and later impaired consciousness, requiring intubation. A repeat brain MRI demonstrated new bilateral supratentorial lesions associated with venous sinus thrombosis, hemorrhage, and midline shift. Anti-MOG antibody was present at a high titer. CSF IL-6 protein was >2,000 times above the upper limits of normal. He improved after plasma exchange, then began monthly treatment alone with anti-IL-6 receptor antibody, tocilizumab, and has remained stable. This case highlights how adult-onset MOGAD, like childhood ADEM, can rapidly become life-threatening. The markedly elevated CSF IL-6 observed here supports consideration for evaluating CSF cytokines more broadly in patients with acute MOGAD.


Asunto(s)
Encefalomielitis Aguda Diseminada , Masculino , Adulto , Humanos , Niño , Interleucina-6/metabolismo , Glicoproteína Mielina-Oligodendrócito , Encéfalo/patología , Citocinas/metabolismo
3.
JBJS Case Connect ; 13(4)2023 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-38134302

RESUMEN

CASE: This is the first documented case of an isolated traumatic vastus medialis rupture that occurred in a 14-year-old athlete after direct impact during play. Imaging confirmed a rare mid-substance rupture. The patient underwent conservative management with physical therapy augmented by blood flow restriction therapy (BFRT) and platelet-poor plasma (PPP) injection to regain full function. CONCLUSION: Isolated quadriceps mid-substance tears are rare. Determining an appropriate treatment technique for mid-substance tears is complex. This case documents the use of nonoperative management with BFRT and PPP to achieve full recovery and early return to play in a young athlete.


Asunto(s)
Lesiones del Ligamento Cruzado Anterior , Músculo Cuádriceps , Humanos , Adolescente , Músculo Cuádriceps/diagnóstico por imagen , Lesiones del Ligamento Cruzado Anterior/cirugía , Rotura/etiología , Modalidades de Fisioterapia
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