Ion-Induced Swelling Behavior of Articular Cartilage due to Non-Newtonian Flow and Its Effects on Fluid Pressure and Solid Displacement.

In this study, we examine the behavior of articular cartilage equilibrated in a salt (NaCl) solution during non-Newtonian fluid flow that follows an Ostwald-de Waele model. A linearly elastic and isotropic rectangular strip of cartilage is considered for analysis. A continuum theory of mixtures has been employed to develop a coupled system of partial differential equations for the solid displacement and the fluid pressure by considering the important factor of the ion concentration by assuming the cartilage as a deformable porous media. The coupled system of partial differential equations is solved using the numerical method named method of lines. In most cases, shear-thinning fluid is compared to the shear-thickening fluid to magnify the difference. Graphical results show that shear-thickening fluids bring more solid deformation and shows less fluid pressure in comparison to the shear-thinning fluids.

Compressive stress relaxation behavior of articular cartilage and its effects on fluid pressure and solid displacement due to non-Newtonian flow.

In this study, we investigate the effects of the power-law index and permeability parameter on the deformation of soft tissue (articular cartilage) which is bathed in the non-Newtonian fluid under stress-relaxation in compression. Ramp displacement is imposed on the surface of hydrated soft tissue. Deformation of the tissue and the fluid pressure is examined for the fast and slow rate of compression. We have employed a linear biphasic mixture theory to develop a mathematical model for compressive stress-relaxation behavior of articular cartilage for non-Newtonian flow. Numerical results indicate that shear-thinning fluids induce less solid deformation and exhibit more fluid pressure as compared to shear-thickening fluids for fast and slow rate of compression. The results also show that linear permeability induces more deformation as compared to strain-dependent nonlinear permeability due to viscoelastic nature of articular cartilage.